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The map label for this gene is resA [H]

Identifier: 78047863

GI number: 78047863

Start: 2639893

End: 2640729

Strand: Reverse

Name: resA [H]

Synonym: XCV2307

Alternate gene names: 78047863

Gene position: 2640729-2639893 (Counterclockwise)

Preceding gene: 78047864

Following gene: 78047862

Centisome position: 50.99

GC content: 61.29

Gene sequence:

>837_bases
ATGATCAGCGTGGGGCCTTTCTCCGTCCAGGTCGTGGCTGTCTTCGCTGCCGTGCTGCTGGCCTGGGCAGTAGCTCGCAT
GGTTGCCAAGCGACTGCCCGACTCGCCGTACAAGGCGGCCGGCGGAATGCTTATGGACGCGGTGTTCCTGGGATTTGTAG
CAGCTCGCCTGGGCTATATCGCGCAGTGGTGGGACGAGTACGCGCAGTCGCCAATGTCCATGTTCTTCATCGGCGACCAA
GGCTTCACCTGGTGGATAGGTGTCGCGGCAACGCTGGTGTTCATCTGGTGGCGCACCCGTTCGACCCGGGCATTGCGCCG
CCCTGTACTGGTAGGTGTTACAGCCGGACTTTTGGCGTGGTTTGCCGCAGGTGGCGTGCTTGAGCTGTTGCAGCGCTCGG
CACCGCCGCTGCCAGCCTTGGCGCTCGCCACGCTCGACGAAAAGCCTGTTGTCCTGAACTCCTATATCGGACGGCCAGTC
GTGCTCAACCTCTGGGCTTCATGGTGTCCGCCATGCCGTCGCGAAATGCCGGTGTTCGAGCAGGCGCAAGCGCAGTATCC
CGAGATCGCTTTCGTCATGGTCAACCAGGGTGAAAGCGCCCAGCAGGCGCGTGCTTTTCTCGAAGCCCAAGGCCTGCAGC
TCAAGGATGTGTTGCTCGACCCGGCTTCCCAAACCATGCAGGCGGTTGCTTCGCGAGGCCTGCCCACCACGTTGTTCTTC
AATGAGCACGGACGCCTGGTGGATACGCACCTGGGCGAACTCTCGATGGCCAGCCTCAAAAACACGGTGTCGCGCCGTTT
CGCGCAATCCCAACAGATCAAGACAGAAAAGGAATAA

Upstream 100 bases:

>100_bases
TTCTGGTTGGCCCGGACGGCAAGGAACGCCGGGATCTGCGCGTGGTGGGTGAGATCGATGCTCGCACCTTCCTGGATCAT
CTGGACAAGGCGGGCTCCTG

Downstream 100 bases:

>100_bases
CCATGTTTGCAAAACGCTCTCGCATTTCCCTCTTTTTGGCCGCCAGCCTGCTGTTGGTCACCGGCTGCAGCCAGGCGGAA
ACCGCCAACCAGCCGCCCGC

Product: putative thiol disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MISVGPFSVQVVAVFAAVLLAWAVARMVAKRLPDSPYKAAGGMLMDAVFLGFVAARLGYIAQWWDEYAQSPMSMFFIGDQ
GFTWWIGVAATLVFIWWRTRSTRALRRPVLVGVTAGLLAWFAAGGVLELLQRSAPPLPALALATLDEKPVVLNSYIGRPV
VLNLWASWCPPCRREMPVFEQAQAQYPEIAFVMVNQGESAQQARAFLEAQGLQLKDVLLDPASQTMQAVASRGLPTTLFF
NEHGRLVDTHLGELSMASLKNTVSRRFAQSQQIKTEKE

Sequences:

>Translated_278_residues
MISVGPFSVQVVAVFAAVLLAWAVARMVAKRLPDSPYKAAGGMLMDAVFLGFVAARLGYIAQWWDEYAQSPMSMFFIGDQ
GFTWWIGVAATLVFIWWRTRSTRALRRPVLVGVTAGLLAWFAAGGVLELLQRSAPPLPALALATLDEKPVVLNSYIGRPV
VLNLWASWCPPCRREMPVFEQAQAQYPEIAFVMVNQGESAQQARAFLEAQGLQLKDVLLDPASQTMQAVASRGLPTTLFF
NEHGRLVDTHLGELSMASLKNTVSRRFAQSQQIKTEKE
>Mature_278_residues
MISVGPFSVQVVAVFAAVLLAWAVARMVAKRLPDSPYKAAGGMLMDAVFLGFVAARLGYIAQWWDEYAQSPMSMFFIGDQ
GFTWWIGVAATLVFIWWRTRSTRALRRPVLVGVTAGLLAWFAAGGVLELLQRSAPPLPALALATLDEKPVVLNSYIGRPV
VLNLWASWCPPCRREMPVFEQAQAQYPEIAFVMVNQGESAQQARAFLEAQGLQLKDVLLDPASQTMQAVASRGLPTTLFF
NEHGRLVDTHLGELSMASLKNTVSRRFAQSQQIKTEKE

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 30687; Mature: 30687

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVGPFSVQVVAVFAAVLLAWAVARMVAKRLPDSPYKAAGGMLMDAVFLGFVAARLGYI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQWWDEYAQSPMSMFFIGDQGFTWWIGVAATLVFIWWRTRSTRALRRPVLVGVTAGLLAW
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
FAAGGVLELLQRSAPPLPALALATLDEKPVVLNSYIGRPVVLNLWASWCPPCRREMPVFE
HHHCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCHHHCCCHHH
QAQAQYPEIAFVMVNQGESAQQARAFLEAQGLQLKDVLLDPASQTMQAVASRGLPTTLFF
HHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEE
NEHGRLVDTHLGELSMASLKNTVSRRFAQSQQIKTEKE
CCCCCEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISVGPFSVQVVAVFAAVLLAWAVARMVAKRLPDSPYKAAGGMLMDAVFLGFVAARLGYI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQWWDEYAQSPMSMFFIGDQGFTWWIGVAATLVFIWWRTRSTRALRRPVLVGVTAGLLAW
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHH
FAAGGVLELLQRSAPPLPALALATLDEKPVVLNSYIGRPVVLNLWASWCPPCRREMPVFE
HHHCHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHCCCHHHCCCHHH
QAQAQYPEIAFVMVNQGESAQQARAFLEAQGLQLKDVLLDPASQTMQAVASRGLPTTLFF
HHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEE
NEHGRLVDTHLGELSMASLKNTVSRRFAQSQQIKTEKE
CCCCCEEHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]