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The map label for this gene is dsbG [H]

Identifier: 78047862

GI number: 78047862

Start: 2639117

End: 2639890

Strand: Reverse

Name: dsbG [H]

Synonym: XCV2306

Alternate gene names: 78047862

Gene position: 2639890-2639117 (Counterclockwise)

Preceding gene: 78047863

Following gene: 78047861

Centisome position: 50.98

GC content: 60.72

Gene sequence:

>774_bases
ATGTTTGCAAAACGCTCTCGCATTTCCCTCTTTTTGGCCGCCAGCCTGCTGTTGGTCACCGGCTGCAGCCAGGCGGAAAC
CGCCAACCAGCCGCCCGCCCTGAAGGCGCTGGAGGATCAGGGCCTGACCGTCATGCAGGAATTCAAGGTCGGAGGCGGAC
TGCGCGCTTTCGCGGCAGTTGCCGGTGACAGGCCCGTCGCCATTTACATCACGAGCGATGGCAATGCCATCGTGGGAACA
CGCCTGAATGCCAAGGGAGAGCCGATCGATGAGGCAGCCCTGAACAATCTGGCGGCCAAGCCGCTCAGCGACAAGGAATG
GGCGCAGCTCCAATCTGCAACCTCTGTCCGGGACGGGCAAGCGAATGCCCCGCGCATCGTGTATGCCTTCTCCGACGCCA
ACTGTCCCTATTGCCATCGCTTCTGGGAAGCCGCACGTCCTTGGGTCGATGCTGGCAAGGTCCAGATTCGGCACATCATG
GTCGGAATCATCAGGGAAGACAGTCCCGCCAAAGCTGCGGCAATCCTGGGTGCCGCTGATCCCTCGGCAGCGTTGCTGGA
AAACGAGCGGAAGTATTCCCAGGGCGGGATTACACCGGCCAAGAGCATTCCAGCAAATGTACGGAAGACCCTCGATGACA
ACCAGATGCTGATGTTGAGCATGGGCTTCCGCGGAACTCCTGGCATCGTCGTTCGTGGCCCCGATGGCGTACTCAAGAAA
TATAACGGCATGCCTCAGGGGCCCCAGTTGGCCGAGGTGCTGGGACCACGCTGA

Upstream 100 bases:

>100_bases
TGGATACGCACCTGGGCGAACTCTCGATGGCCAGCCTCAAAAACACGGTGTCGCGCCGTTTCGCGCAATCCCAACAGATC
AAGACAGAAAAGGAATAACC

Downstream 100 bases:

>100_bases
GACCCATCCTTTGGCGCGCGAATGCGATATGTGCCGCATCGCGCGCCAGAGCTGCACCTACTGGGCTAACCAACTGCAAT
TCAAGGAGGTGAATCATGTC

Product: disulfide isomerase/thiol-disulfide oxidase

Products: protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MFAKRSRISLFLAASLLLVTGCSQAETANQPPALKALEDQGLTVMQEFKVGGGLRAFAAVAGDRPVAIYITSDGNAIVGT
RLNAKGEPIDEAALNNLAAKPLSDKEWAQLQSATSVRDGQANAPRIVYAFSDANCPYCHRFWEAARPWVDAGKVQIRHIM
VGIIREDSPAKAAAILGAADPSAALLENERKYSQGGITPAKSIPANVRKTLDDNQMLMLSMGFRGTPGIVVRGPDGVLKK
YNGMPQGPQLAEVLGPR

Sequences:

>Translated_257_residues
MFAKRSRISLFLAASLLLVTGCSQAETANQPPALKALEDQGLTVMQEFKVGGGLRAFAAVAGDRPVAIYITSDGNAIVGT
RLNAKGEPIDEAALNNLAAKPLSDKEWAQLQSATSVRDGQANAPRIVYAFSDANCPYCHRFWEAARPWVDAGKVQIRHIM
VGIIREDSPAKAAAILGAADPSAALLENERKYSQGGITPAKSIPANVRKTLDDNQMLMLSMGFRGTPGIVVRGPDGVLKK
YNGMPQGPQLAEVLGPR
>Mature_257_residues
MFAKRSRISLFLAASLLLVTGCSQAETANQPPALKALEDQGLTVMQEFKVGGGLRAFAAVAGDRPVAIYITSDGNAIVGT
RLNAKGEPIDEAALNNLAAKPLSDKEWAQLQSATSVRDGQANAPRIVYAFSDANCPYCHRFWEAARPWVDAGKVQIRHIM
VGIIREDSPAKAAAILGAADPSAALLENERKYSQGGITPAKSIPANVRKTLDDNQMLMLSMGFRGTPGIVVRGPDGVLKK
YNGMPQGPQLAEVLGPR

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=232, Percent_Identity=37.0689655172414, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27366; Mature: 27366

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAKRSRISLFLAASLLLVTGCSQAETANQPPALKALEDQGLTVMQEFKVGGGLRAFAAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEHHHCCCCHHHHHHH
AGDRPVAIYITSDGNAIVGTRLNAKGEPIDEAALNNLAAKPLSDKEWAQLQSATSVRDGQ
CCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ANAPRIVYAFSDANCPYCHRFWEAARPWVDAGKVQIRHIMVGIIREDSPAKAAAILGAAD
CCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCHHEEEEECCC
PSAALLENERKYSQGGITPAKSIPANVRKTLDDNQMLMLSMGFRGTPGIVVRGPDGVLKK
CHHHHHHCCHHHHCCCCCCHHCCCHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHH
YNGMPQGPQLAEVLGPR
CCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MFAKRSRISLFLAASLLLVTGCSQAETANQPPALKALEDQGLTVMQEFKVGGGLRAFAAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEEHHHCCCCHHHHHHH
AGDRPVAIYITSDGNAIVGTRLNAKGEPIDEAALNNLAAKPLSDKEWAQLQSATSVRDGQ
CCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ANAPRIVYAFSDANCPYCHRFWEAARPWVDAGKVQIRHIMVGIIREDSPAKAAAILGAAD
CCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCHHEEEEECCC
PSAALLENERKYSQGGITPAKSIPANVRKTLDDNQMLMLSMGFRGTPGIVVRGPDGVLKK
CHHHHHHCCHHHHCCCCCCHHCCCHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHH
YNGMPQGPQLAEVLGPR
CCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein with reduced SH groups [C]

Specific reaction: protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]