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The map label for this gene is dfrA [H]

Identifier: 78047609

GI number: 78047609

Start: 2336187

End: 2337230

Strand: Reverse

Name: dfrA [H]

Synonym: XCV2053

Alternate gene names: 78047609

Gene position: 2337230-2336187 (Counterclockwise)

Preceding gene: 78047610

Following gene: 78047608

Centisome position: 45.13

GC content: 64.75

Gene sequence:

>1044_bases
ATGAAGCAAACGGTGTTGGTCACCGGCGGTAGTGGCTATGTCGCCTGCCGGCTGGTGAAGCAGTTGCTGGAAGCGGGCGA
CACCGTGCACGCCACCGTGCGCAGCCTGCACGATTCGCCCAAGCTGCGGCCTTTACGGCAGCTGCAGGCGGACCACCCGG
ACCAATTGCGGTTGTTCGAAGCAGACCTGCTGGTACCCGGCTCCTTCGTCGGTGCGATGCAGGGCTGCTCTGTGGTGCAT
CACGTCGCCTCGCCGTTCCTGATGCCGGAAAAGATCAAGAACGGCCGCACCCAACTGCTGGAACCCGCGCTGCAAGGCGT
CAGGAACGTGCTGACCACGGTGAACGCGACTTCCAGCGTCGAGCGGGTGGTGCTCACGTCCACCATCGGCGCGATCTTCG
GCGACTACCGCGACGTGCTGGACATGCCCGGGCAAACGCTGTCAGAAGCCTTCTTCAACACCACCAGCAGCCTCGATCAC
AATCCCTACCACTACTCCAAGGTGGTCGCCGAGCAGGAGGCGTGGGCCATGTACCGTGCGCAGCAGCGCTGGGACCTGGT
CTGCATCAATCCCGGCCTGGTGCTCGGTCCGTCCCCGGCCGCAGGCTCGGATTCGGGCAGCCTGTTCCTGCTCGACGAAC
TGATGCGCGGCCTGTTCTTCTATGGCGTGCCGGACCTGAGCTTTGCCACGGTGGACGTGCGTGAAGTTGCCAACGCACAC
ATCGCCGCGGCCAAGCGGCCCAGCGCGCACGGCCGCTACATCGTCGCCTCGGCACAGATGATCTCGTTCCTGGAAATCGC
GCGGTTCCTGCGCAAGGTCCACCGCCGCCCTTACCTGTTGCCGCGTCTGCAGATTCCCGGTTTGGCGTTGCGGCTACTCG
GCCCCTTCTTCGGGCTGAGCCCCAAGTACATTCGCAATCATCTCGGCATCCGCTTCGGCCTGGACAACCGGCGCTCGCGC
CAGGAATTGGGCGTGGACTACCGTCCGGTCGAGCAGACCTTGCACGAGCACTACGCCAGCTGGGACCGGCAGCGACGGGC
TTGA

Upstream 100 bases:

>100_bases
CGTGCCTGGTACCCGATCATTCCGAACTTGCGGACGCTACCGCAGAATATGCTAGCGTTGACTATTGATTCGGGCATGTC
GCCCGCACCGGAATCGGCCC

Downstream 100 bases:

>100_bases
GCCAGCTGGGTGCTCCGCAGGCGCACCTGTACCATCGCCGGAACCGAACCAGGCACCTGCCCATGCCCTTTGCCGCTCCA
TTTCCATGCCTGCGTGGCGC

Product: putative cinnamoyl-CoA reductase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKQTVLVTGGSGYVACRLVKQLLEAGDTVHATVRSLHDSPKLRPLRQLQADHPDQLRLFEADLLVPGSFVGAMQGCSVVH
HVASPFLMPEKIKNGRTQLLEPALQGVRNVLTTVNATSSVERVVLTSTIGAIFGDYRDVLDMPGQTLSEAFFNTTSSLDH
NPYHYSKVVAEQEAWAMYRAQQRWDLVCINPGLVLGPSPAAGSDSGSLFLLDELMRGLFFYGVPDLSFATVDVREVANAH
IAAAKRPSAHGRYIVASAQMISFLEIARFLRKVHRRPYLLPRLQIPGLALRLLGPFFGLSPKYIRNHLGIRFGLDNRRSR
QELGVDYRPVEQTLHEHYASWDRQRRA

Sequences:

>Translated_347_residues
MKQTVLVTGGSGYVACRLVKQLLEAGDTVHATVRSLHDSPKLRPLRQLQADHPDQLRLFEADLLVPGSFVGAMQGCSVVH
HVASPFLMPEKIKNGRTQLLEPALQGVRNVLTTVNATSSVERVVLTSTIGAIFGDYRDVLDMPGQTLSEAFFNTTSSLDH
NPYHYSKVVAEQEAWAMYRAQQRWDLVCINPGLVLGPSPAAGSDSGSLFLLDELMRGLFFYGVPDLSFATVDVREVANAH
IAAAKRPSAHGRYIVASAQMISFLEIARFLRKVHRRPYLLPRLQIPGLALRLLGPFFGLSPKYIRNHLGIRFGLDNRRSR
QELGVDYRPVEQTLHEHYASWDRQRRA
>Mature_347_residues
MKQTVLVTGGSGYVACRLVKQLLEAGDTVHATVRSLHDSPKLRPLRQLQADHPDQLRLFEADLLVPGSFVGAMQGCSVVH
HVASPFLMPEKIKNGRTQLLEPALQGVRNVLTTVNATSSVERVVLTSTIGAIFGDYRDVLDMPGQTLSEAFFNTTSSLDH
NPYHYSKVVAEQEAWAMYRAQQRWDLVCINPGLVLGPSPAAGSDSGSLFLLDELMRGLFFYGVPDLSFATVDVREVANAH
IAAAKRPSAHGRYIVASAQMISFLEIARFLRKVHRRPYLLPRLQIPGLALRLLGPFFGLSPKYIRNHLGIRFGLDNRRSR
QELGVDYRPVEQTLHEHYASWDRQRRA

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=335, Percent_Identity=31.9402985074627, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320750, Length=357, Percent_Identity=29.1316526610644, Blast_Score=112, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324421, Length=349, Percent_Identity=26.647564469914, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321281, Length=354, Percent_Identity=25.7062146892655, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321399, Length=343, Percent_Identity=24.7813411078717, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 38704; Mature: 38704

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTVLVTGGSGYVACRLVKQLLEAGDTVHATVRSLHDSPKLRPLRQLQADHPDQLRLFE
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEE
ADLLVPGSFVGAMQGCSVVHHVASPFLMPEKIKNGRTQLLEPALQGVRNVLTTVNATSSV
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
ERVVLTSTIGAIFGDYRDVLDMPGQTLSEAFFNTTSSLDHNPYHYSKVVAEQEAWAMYRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
QQRWDLVCINPGLVLGPSPAAGSDSGSLFLLDELMRGLFFYGVPDLSFATVDVREVANAH
HCCCCEEEECCCEEECCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
IAAAKRPSAHGRYIVASAQMISFLEIARFLRKVHRRPYLLPRLQIPGLALRLLGPFFGLS
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
PKYIRNHLGIRFGLDNRRSRQELGVDYRPVEQTLHEHYASWDRQRRA
HHHHHHHCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQTVLVTGGSGYVACRLVKQLLEAGDTVHATVRSLHDSPKLRPLRQLQADHPDQLRLFE
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEE
ADLLVPGSFVGAMQGCSVVHHVASPFLMPEKIKNGRTQLLEPALQGVRNVLTTVNATSSV
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHH
ERVVLTSTIGAIFGDYRDVLDMPGQTLSEAFFNTTSSLDHNPYHYSKVVAEQEAWAMYRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
QQRWDLVCINPGLVLGPSPAAGSDSGSLFLLDELMRGLFFYGVPDLSFATVDVREVANAH
HCCCCEEEECCCEEECCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
IAAAKRPSAHGRYIVASAQMISFLEIARFLRKVHRRPYLLPRLQIPGLALRLLGPFFGLS
HHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
PKYIRNHLGIRFGLDNRRSRQELGVDYRPVEQTLHEHYASWDRQRRA
HHHHHHHCCEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]