Click here to switch to the map view.

The map label for this gene is aat

Identifier: 78047608

GI number: 78047608

Start: 2335304

End: 2336056

Strand: Reverse

Name: aat

Synonym: XCV2052

Alternate gene names: 78047608

Gene position: 2336056-2335304 (Counterclockwise)

Preceding gene: 78047609

Following gene: 78047607

Centisome position: 45.11

GC content: 65.6

Gene sequence:

>753_bases
ATGACGCCCTTTCGTCGTCCCACCGTGTTGGGCACTTCCGCCTCGGCCCCATTCCCGCCTGCCGAGGCCGCCCTGACCGA
TCCCGACGGACTGCTTGCCGTTGGCGGAGATCTGTCGCCCCAGCGCCTGCTCAACGCGTACGCGCACGGCATTTTCCCGT
GGTATTCGGAGGGCCAACCGATCCTGTGGTGGAGCCCGGATCCGCGCATGGTCTTTCGCACTGACGGCGTGCGCCTGTCC
TCTCGCTTCAAGCGCCAGCTTCGCGCAAGCACCTGGACGGTTCGCGCCGATACCGCCTTCGAACAGGTGATCGACGCCTG
TGCTGCGAGTCCGCGCCCTGGCCAGGACGGCACCTGGATCACCGCGGAAATGCAGCAGGCCTATATCGCCTTGCACCGTC
TCGGCCACGCGCATTCGATCGAGGTGTTCGACGGCGCGCGCCTGGTTGGCGGGATCTACGGCGTCGCGATCGGCCGGATG
TTTTTTGGCGAAAGCATGTTCAGCGGGGAAAGCGGCGGCTCCAAGGTGGCACTAGCCGCCTTGGCCGCCAATCTGCATGG
CCGAGGGTGGCCACTGATCGATGCGCAGGTGGAAAATCCGCACCTGCTGAGCCTGGGCGCCGAACGCTTGCCGCGCGCTG
ACTTTTTGCACCAGGTGCAACGCCAGGTTGCCCTGACGGAACCGCCGGGTAGTTGGTCTGCGCGTTACGGCGAACACGCC
GCCAGCGGGCTGTGTGAGACCCGCTTAACATAA

Upstream 100 bases:

>100_bases
ACCATCGCCGGAACCGAACCAGGCACCTGCCCATGCCCTTTGCCGCTCCATTTCCATGCCTGCGTGGCGCGCCGTGGCGA
TCCGGCCGGTGGCCGGCGTG

Downstream 100 bases:

>100_bases
AATTTGCACCGCGGGGAGATGGCGCGTAAAATGCCGTCCCTTACGGCCCTGCCGGGCCAGCCGTGACTGCACAGGATTAC
ATGTCGAAAGACGACTCCAT

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTPFRRPTVLGTSASAPFPPAEAALTDPDGLLAVGGDLSPQRLLNAYAHGIFPWYSEGQPILWWSPDPRMVFRTDGVRLS
SRFKRQLRASTWTVRADTAFEQVIDACAASPRPGQDGTWITAEMQQAYIALHRLGHAHSIEVFDGARLVGGIYGVAIGRM
FFGESMFSGESGGSKVALAALAANLHGRGWPLIDAQVENPHLLSLGAERLPRADFLHQVQRQVALTEPPGSWSARYGEHA
ASGLCETRLT

Sequences:

>Translated_250_residues
MTPFRRPTVLGTSASAPFPPAEAALTDPDGLLAVGGDLSPQRLLNAYAHGIFPWYSEGQPILWWSPDPRMVFRTDGVRLS
SRFKRQLRASTWTVRADTAFEQVIDACAASPRPGQDGTWITAEMQQAYIALHRLGHAHSIEVFDGARLVGGIYGVAIGRM
FFGESMFSGESGGSKVALAALAANLHGRGWPLIDAQVENPHLLSLGAERLPRADFLHQVQRQVALTEPPGSWSARYGEHA
ASGLCETRLT
>Mature_249_residues
TPFRRPTVLGTSASAPFPPAEAALTDPDGLLAVGGDLSPQRLLNAYAHGIFPWYSEGQPILWWSPDPRMVFRTDGVRLSS
RFKRQLRASTWTVRADTAFEQVIDACAASPRPGQDGTWITAEMQQAYIALHRLGHAHSIEVFDGARLVGGIYGVAIGRMF
FGESMFSGESGGSKVALAALAANLHGRGWPLIDAQVENPHLLSLGAERLPRADFLHQVQRQVALTEPPGSWSARYGEHAA
SGLCETRLT

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=221, Percent_Identity=49.7737556561086, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_XANC5 (Q3BTY0)

Other databases:

- EMBL:   AM039952
- RefSeq:   YP_363783.1
- HSSP:   P0A8P1
- ProteinModelPortal:   Q3BTY0
- SMR:   Q3BTY0
- STRING:   Q3BTY0
- GeneID:   3732921
- GenomeReviews:   AM039952_GR
- KEGG:   xcv:XCV2052
- NMPDR:   fig|316273.3.peg.1811
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- ProtClustDB:   PRK00301
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 27130; Mature: 26999

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFRRPTVLGTSASAPFPPAEAALTDPDGLLAVGGDLSPQRLLNAYAHGIFPWYSEGQP
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCE
ILWWSPDPRMVFRTDGVRLSSRFKRQLRASTWTVRADTAFEQVIDACAASPRPGQDGTWI
EEEECCCCCEEEEECCEEHHHHHHHHHHHHEEEEECHHHHHHHHHHHHCCCCCCCCCCEE
TAEMQQAYIALHRLGHAHSIEVFDGARLVGGIYGVAIGRMFFGESMFSGESGGSKVALAA
EHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEHHH
LAANLHGRGWPLIDAQVENPHLLSLGAERLPRADFLHQVQRQVALTEPPGSWSARYGEHA
HHHHCCCCCCCEEEEECCCCEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ASGLCETRLT
HHCCHHHCCC
>Mature Secondary Structure 
TPFRRPTVLGTSASAPFPPAEAALTDPDGLLAVGGDLSPQRLLNAYAHGIFPWYSEGQP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCE
ILWWSPDPRMVFRTDGVRLSSRFKRQLRASTWTVRADTAFEQVIDACAASPRPGQDGTWI
EEEECCCCCEEEEECCEEHHHHHHHHHHHHEEEEECHHHHHHHHHHHHCCCCCCCCCCEE
TAEMQQAYIALHRLGHAHSIEVFDGARLVGGIYGVAIGRMFFGESMFSGESGGSKVALAA
EHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEHHH
LAANLHGRGWPLIDAQVENPHLLSLGAERLPRADFLHQVQRQVALTEPPGSWSARYGEHA
HHHHCCCCCCCEEEEECCCCEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
ASGLCETRLT
HHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA