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The map label for this gene is moaB [H]

Identifier: 78046529

GI number: 78046529

Start: 1102389

End: 1102907

Strand: Reverse

Name: moaB [H]

Synonym: XCV0973

Alternate gene names: 78046529

Gene position: 1102907-1102389 (Counterclockwise)

Preceding gene: 78046530

Following gene: 78046528

Centisome position: 21.3

GC content: 65.7

Gene sequence:

>519_bases
ATGCCTTCCACTCTCGACTTCATTCCCTTGCGCCTGTGCGTGCTGACGGTGTCCGACAGCCGCACGCTGGCCGACGATCG
CTCCGGCGATTACCTGGCCGATGCCCTCACCCACGAAGGCCATGTGCTGCACGAACGTGCACTGTGCCCGGACGACCGTT
ACCGCATGCGTGCGATCGTGTCGCGCTGGATTGCCGATGCGCAGGTCGACGGCATCCTGATCACCGGCGGCACCGGCTTC
ACCGGTCGCGACAGCACCCCGGAAGCGATCACCCCGTTGCTGGACAAGGTCATGCCTGGCTTCGGCGAGATGTTCCGCGC
GATCAGCGTGGAAGAAATCGGTACCTCCTCGCTGCAGTCGCGCGCCTTTGCCGGGCTGGCCAATCACAGCTTCGTGTTCT
GCCTGCCCGGCTCCACCTCGGCCTGCCGCACGGCCTGGGAGAAGATCGTGCGTGCGCAGCTGGATGCGCGCACCAGGCCC
TGCAATCTGGCGACATTGCGTCCACGCCTGGGGCAATAG

Upstream 100 bases:

>100_bases
CCGCGGCCGCGCTGTCGCCCTGACCGACGCCAGCAGCTGCGTTGTGCGGCTTCACGCCGTGGTGCTGTACCCGGTCGTCC
CGGCTCGCTAGGCTTGTGGC

Downstream 100 bases:

>100_bases
CCTGCGCGCTCTCCACTGTTGCTGGAACGCGCATGTCGCACCTGAAACGCAAGGCCTATAAAAAGTTGCTGGCGCCGATG
CAGCTGGAGCTGGTGGACAT

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPSTLDFIPLRLCVLTVSDSRTLADDRSGDYLADALTHEGHVLHERALCPDDRYRMRAIVSRWIADAQVDGILITGGTGF
TGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTRP
CNLATLRPRLGQ

Sequences:

>Translated_172_residues
MPSTLDFIPLRLCVLTVSDSRTLADDRSGDYLADALTHEGHVLHERALCPDDRYRMRAIVSRWIADAQVDGILITGGTGF
TGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTRP
CNLATLRPRLGQ
>Mature_171_residues
PSTLDFIPLRLCVLTVSDSRTLADDRSGDYLADALTHEGHVLHERALCPDDRYRMRAIVSRWIADAQVDGILITGGTGFT
GRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQSRAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTRPC
NLATLRPRLGQ

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=150, Percent_Identity=32, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI10880983, Length=150, Percent_Identity=32, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1787000, Length=158, Percent_Identity=56.3291139240506, Blast_Score=190, Evalue=4e-50,
Organism=Escherichia coli, GI1786190, Length=150, Percent_Identity=29.3333333333333, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18821; Mature: 18690

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTLDFIPLRLCVLTVSDSRTLADDRSGDYLADALTHEGHVLHERALCPDDRYRMRAIV
CCCCHHHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCHHHHHHHHH
SRWIADAQVDGILITGGTGFTGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQS
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
RAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTRPCNLATLRPRLGQ
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
PSTLDFIPLRLCVLTVSDSRTLADDRSGDYLADALTHEGHVLHERALCPDDRYRMRAIV
CCCHHHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCHHHHHHHHH
SRWIADAQVDGILITGGTGFTGRDSTPEAITPLLDKVMPGFGEMFRAISVEEIGTSSLQS
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
RAFAGLANHSFVFCLPGSTSACRTAWEKIVRAQLDARTRPCNLATLRPRLGQ
HHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]