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The map label for this gene is cobP [H]

Identifier: 78044997

GI number: 78044997

Start: 675174

End: 675680

Strand: Direct

Name: cobP [H]

Synonym: CHY_0768

Alternate gene names: 78044997

Gene position: 675174-675680 (Clockwise)

Preceding gene: 78043271

Following gene: 78043382

Centisome position: 28.11

GC content: 47.73

Gene sequence:

>507_bases
GTGAAGGTGTTAATTACCGGTGGGGTGCGTTCGGGCAAAAGTAGTTTTGCGGAAAAGTTAGCGACCTCTTTCGGGGAAAA
AGTGGTATATGTGGCTACCGCTACTGCCGGGGACGAAGAGATGCGTGAGCGGATTGCCAAACATCAAAGCCGTCGTCCCC
CTAACTGGGTCACGGTGGAGGAGCCGGTAAATTTACGGGACGTTCTTTTAACAGCCCGGGGAGATGCGGTTCTGGTCGAT
TGTCTAACCCTCTGGGTTACCAATTTACTTCTTAAAGAAGAAGATGTGGTTGGTAAAGCTTATGAAGTAGTAGAAATATT
TCCCAGGATTACCGTTCCGCTTATCTTTGTTACCAACGAAGTAGGTTCAGGAATTGTTCCCGATAACCCGTTAGCCCGTA
AGTTTAGGGATGTAGCCGGCCTTGTCAACCAAGTTTTTGCAAAGTATTGCGATGAAGTTTACCTTACCGTGGCGGGAATA
CCGGTAAAAATCAAGGGGGTGAACTAA

Upstream 100 bases:

>100_bases
GTGCCGTATATCACGTTACTGGGTACTAAAGGGGGTAGTACCATTGCGGCAGCAATAGTTAATGCTTTAATTAAATTATC
CAGGACCGGAGGGAAATAAA

Downstream 100 bases:

>100_bases
TGGCCAGGGCGATAATGTTTCAGGGAACCGCCAGCCATGTAGGAAAATCGGTGCTGACTTTAGCTTTAGCCCGGGTGCTT
TATCTGGACGGCTTTAAAGT

Product: cobalamin biosynthesis protein CobP

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPNWVTVEEPVNLRDVLLTARGDAVLVD
CLTLWVTNLLLKEEDVVGKAYEVVEIFPRITVPLIFVTNEVGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGI
PVKIKGVN

Sequences:

>Translated_168_residues
MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPNWVTVEEPVNLRDVLLTARGDAVLVD
CLTLWVTNLLLKEEDVVGKAYEVVEIFPRITVPLIFVTNEVGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGI
PVKIKGVN
>Mature_168_residues
MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPNWVTVEEPVNLRDVLLTARGDAVLVD
CLTLWVTNLLLKEEDVVGKAYEVVEIFPRITVPLIFVTNEVGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGI
PVKIKGVN

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=183, Percent_Identity=41.5300546448087, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18458; Mature: 18458

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPNWVTVE
CEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEC
EPVNLRDVLLTARGDAVLVDCLTLWVTNLLLKEEDVVGKAYEVVEIFPRITVPLIFVTNE
CCCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHEEEEEEECC
VGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGIPVKIKGVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEECC
>Mature Secondary Structure
MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPNWVTVE
CEEEEECCCCCCHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEC
EPVNLRDVLLTARGDAVLVDCLTLWVTNLLLKEEDVVGKAYEVVEIFPRITVPLIFVTNE
CCCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHEEEEEEECC
VGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGIPVKIKGVN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]