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The map label for this gene is cobQ

Identifier: 78043382

GI number: 78043382

Start: 675680

End: 677173

Strand: Direct

Name: cobQ

Synonym: CHY_0769

Alternate gene names: 78043382

Gene position: 675680-677173 (Clockwise)

Preceding gene: 78044997

Following gene: 78043696

Centisome position: 28.14

GC content: 45.78

Gene sequence:

>1494_bases
ATGGCCAGGGCGATAATGTTTCAGGGAACCGCCAGCCATGTAGGAAAATCGGTGCTGACTTTAGCTTTAGCCCGGGTGCT
TTATCTGGACGGCTTTAAAGTTGCCCCCTTTAAAGCACAAAATATGGCTCTAAATTCCTACGTAACCCTGGATGGCGGAG
AAATGGGTAGAGCCCAGGTAGCCCAGGCGGAAGCCTGCGGGTTAGAGCCCCGGGTAGAAATGAACCCGGTTTTATTAAAA
CCCTCGTCCGATAAAGGTAGCCAGGTTATAGTTCTGGGGAAACCCATCGGTCACTATTCGGCCAAGAGCTACCATCTTGA
GCGGCGCAGTATGGTTTGGGAAGCGGTAAAAAAAGCTTACGAAACTTTAGCTCAAGAATTTGATTTTATTGTGATTGAAG
GTGCTGGAAGTCCGGCGGAAGTAAATTTAAAAGCTTCCGACATTGCCAATATGAAAACCGCTTTTTTAGCCAATGCCCCG
GTTATTTTAGTGGCCGATATTGACCGGGGAGGAGCGCTTGCTTCCCTGGTGGGGACAATGGAACTTTTAGAGCCCGAGGA
AAGGAAAATGGTGTGCGGCTTTATCTTAAATAAATTCCGGGGAGACCTGGAATTATTAAAGCCTGCCCTTACTTTTTTGG
AAGAAAAAACCGGTATTCCGGTTTTGGGGGTAATGCCTTACATTCCCGAACTTTTAATACCCGAAGAAGATTCGGTAAGT
TTGGAAGAAACTGTTAGTAACCGGGAGAAAGATTTAAAAATTGGCGTGGTGTGGTACCCCAGGATTTCCAATTTTACCGA
TTTTGAAATATTCCAGTATGAACCGGACGTGGAGCTTATTTACATCAAAACTCTTCAGGATTTTCGGGACGATTTTGACC
TGGTAATATTGCCGGGAAGTAAAAACACCGTAGCCGATTTAAACTATTTAAAACAAAGGGGCCTTGACCAAAAGCTCTAC
GCTTATGTAGAGAAAGGAAAACCCCTGATTGGAATTTGCGGGGGTCTTCAGATACTTGGAGAAAAGATTTTGGATCCCGA
TTTGGTGGAAGGGAAGGAAACGGAGGTTAAAGCCTTAGGAATCCTCGATACTGTTACCGAATTTCGCGGGGATAAAATTA
CCCGGCGGACAAGTACCCGGGTTACCAGGGCCGATGGCTATTTCTTTCTCCAGAGGGAAGAAATCTCCGGCTACGAAATT
CACCACGGCCGAACTTTTCTTTCAGGGGAAAGAAGTGATGTATTGGATAATACGGAAAATCCGCTGGTATTTGCCCGCGG
CAGAGTTCTTGGTACCTACCTGCACGGGCTTTTTGATAATGACTTTTTTCGCCATCGCCTTTTAAATCGGTTGCGGCGGG
AAAAAGGGCTTGACGGGATTGAAAACCGCCCGACTTCCTTAAAAAACCTGCGCCAGGAAAATTATGATAAAATAGCCCGG
GTGTTCAGGGAAAACGTTAACTTGAAGAAAATTTACGAGATTCTGGGGATCTGA

Upstream 100 bases:

>100_bases
GGGATGTAGCCGGCCTTGTCAACCAAGTTTTTGCAAAGTATTGCGATGAAGTTTACCTTACCGTGGCGGGAATACCGGTA
AAAATCAAGGGGGTGAACTA

Downstream 100 bases:

>100_bases
GATGAAAGGAATTTTTATTACCGTGGTTATTGCCTTGATACTGGACATTGTCTTTAAGGATCCAGGGCAAGATTATCATC
CGGTAGCTTTAATTGGTCGT

Product: cobyric acid synthase CobQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MARAIMFQGTASHVGKSVLTLALARVLYLDGFKVAPFKAQNMALNSYVTLDGGEMGRAQVAQAEACGLEPRVEMNPVLLK
PSSDKGSQVIVLGKPIGHYSAKSYHLERRSMVWEAVKKAYETLAQEFDFIVIEGAGSPAEVNLKASDIANMKTAFLANAP
VILVADIDRGGALASLVGTMELLEPEERKMVCGFILNKFRGDLELLKPALTFLEEKTGIPVLGVMPYIPELLIPEEDSVS
LEETVSNREKDLKIGVVWYPRISNFTDFEIFQYEPDVELIYIKTLQDFRDDFDLVILPGSKNTVADLNYLKQRGLDQKLY
AYVEKGKPLIGICGGLQILGEKILDPDLVEGKETEVKALGILDTVTEFRGDKITRRTSTRVTRADGYFFLQREEISGYEI
HHGRTFLSGERSDVLDNTENPLVFARGRVLGTYLHGLFDNDFFRHRLLNRLRREKGLDGIENRPTSLKNLRQENYDKIAR
VFRENVNLKKIYEILGI

Sequences:

>Translated_497_residues
MARAIMFQGTASHVGKSVLTLALARVLYLDGFKVAPFKAQNMALNSYVTLDGGEMGRAQVAQAEACGLEPRVEMNPVLLK
PSSDKGSQVIVLGKPIGHYSAKSYHLERRSMVWEAVKKAYETLAQEFDFIVIEGAGSPAEVNLKASDIANMKTAFLANAP
VILVADIDRGGALASLVGTMELLEPEERKMVCGFILNKFRGDLELLKPALTFLEEKTGIPVLGVMPYIPELLIPEEDSVS
LEETVSNREKDLKIGVVWYPRISNFTDFEIFQYEPDVELIYIKTLQDFRDDFDLVILPGSKNTVADLNYLKQRGLDQKLY
AYVEKGKPLIGICGGLQILGEKILDPDLVEGKETEVKALGILDTVTEFRGDKITRRTSTRVTRADGYFFLQREEISGYEI
HHGRTFLSGERSDVLDNTENPLVFARGRVLGTYLHGLFDNDFFRHRLLNRLRREKGLDGIENRPTSLKNLRQENYDKIAR
VFRENVNLKKIYEILGI
>Mature_496_residues
ARAIMFQGTASHVGKSVLTLALARVLYLDGFKVAPFKAQNMALNSYVTLDGGEMGRAQVAQAEACGLEPRVEMNPVLLKP
SSDKGSQVIVLGKPIGHYSAKSYHLERRSMVWEAVKKAYETLAQEFDFIVIEGAGSPAEVNLKASDIANMKTAFLANAPV
ILVADIDRGGALASLVGTMELLEPEERKMVCGFILNKFRGDLELLKPALTFLEEKTGIPVLGVMPYIPELLIPEEDSVSL
EETVSNREKDLKIGVVWYPRISNFTDFEIFQYEPDVELIYIKTLQDFRDDFDLVILPGSKNTVADLNYLKQRGLDQKLYA
YVEKGKPLIGICGGLQILGEKILDPDLVEGKETEVKALGILDTVTEFRGDKITRRTSTRVTRADGYFFLQREEISGYEIH
HGRTFLSGERSDVLDNTENPLVFARGRVLGTYLHGLFDNDFFRHRLLNRLRREKGLDGIENRPTSLKNLRQENYDKIARV
FRENVNLKKIYEILGI

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_CARHZ (Q3AE11)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359623.1
- ProteinModelPortal:   Q3AE11
- STRING:   Q3AE11
- GeneID:   3728767
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0769
- NMPDR:   fig|246194.3.peg.862
- TIGR:   CHY_0769
- eggNOG:   COG1492
- HOGENOM:   HBG302271
- OMA:   RGDIANM
- BioCyc:   CHYD246194:CHY_0769-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 55829; Mature: 55698

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 333-333 ACT_SITE 435-435

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAIMFQGTASHVGKSVLTLALARVLYLDGFKVAPFKAQNMALNSYVTLDGGEMGRAQV
CCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEEEECCCCCCHHHH
AQAEACGLEPRVEMNPVLLKPSSDKGSQVIVLGKPIGHYSAKSYHLERRSMVWEAVKKAY
HHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ETLAQEFDFIVIEGAGSPAEVNLKASDIANMKTAFLANAPVILVADIDRGGALASLVGTM
HHHHHCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
ELLEPEERKMVCGFILNKFRGDLELLKPALTFLEEKTGIPVLGVMPYIPELLIPEEDSVS
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHCCCCCCCCC
LEETVSNREKDLKIGVVWYPRISNFTDFEIFQYEPDVELIYIKTLQDFRDDFDLVILPGS
HHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEHHHHCCCCCEEEECCC
KNTVADLNYLKQRGLDQKLYAYVEKGKPLIGICGGLQILGEKILDPDLVEGKETEVKALG
CCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHH
ILDTVTEFRGDKITRRTSTRVTRADGYFFLQREEISGYEIHHGRTFLSGERSDVLDNTEN
HHHHHHHHCCCCEEEHHCCEEEECCCEEEEEECCCCCEEEECCCEEECCCCHHHCCCCCC
PLVFARGRVLGTYLHGLFDNDFFRHRLLNRLRREKGLDGIENRPTSLKNLRQENYDKIAR
CEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VFRENVNLKKIYEILGI
HHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
ARAIMFQGTASHVGKSVLTLALARVLYLDGFKVAPFKAQNMALNSYVTLDGGEMGRAQV
CCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEEEECCCCCCHHHH
AQAEACGLEPRVEMNPVLLKPSSDKGSQVIVLGKPIGHYSAKSYHLERRSMVWEAVKKAY
HHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
ETLAQEFDFIVIEGAGSPAEVNLKASDIANMKTAFLANAPVILVADIDRGGALASLVGTM
HHHHHCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
ELLEPEERKMVCGFILNKFRGDLELLKPALTFLEEKTGIPVLGVMPYIPELLIPEEDSVS
HHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCHHCCCCCCCCC
LEETVSNREKDLKIGVVWYPRISNFTDFEIFQYEPDVELIYIKTLQDFRDDFDLVILPGS
HHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEHHHHCCCCCEEEECCC
KNTVADLNYLKQRGLDQKLYAYVEKGKPLIGICGGLQILGEKILDPDLVEGKETEVKALG
CCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHH
ILDTVTEFRGDKITRRTSTRVTRADGYFFLQREEISGYEIHHGRTFLSGERSDVLDNTEN
HHHHHHHHCCCCEEEHHCCEEEECCCEEEEEECCCCCEEEECCCEEECCCCHHHCCCCCC
PLVFARGRVLGTYLHGLFDNDFFRHRLLNRLRREKGLDGIENRPTSLKNLRQENYDKIAR
CEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VFRENVNLKKIYEILGI
HHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA