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The map label for this gene is cobH [H]

Identifier: 78043271

GI number: 78043271

Start: 674558

End: 675172

Strand: Direct

Name: cobH [H]

Synonym: CHY_0767

Alternate gene names: 78043271

Gene position: 674558-675172 (Clockwise)

Preceding gene: 78042873

Following gene: 78044997

Centisome position: 28.09

GC content: 45.37

Gene sequence:

>615_bases
ATGAATTATGAATTTTTAATTAATCCCCGGGAGATTGAACAGAAAAGTTTTGCCATTATTGAAAGTTTAACGGGACTTGG
CAATACTCCTGAAGACCAGGTAATTAAACGGGCCATCCATGCATCAGGTGATCCGGAAATCAGAAAGGATTTTCGTTTTC
ATCCCGCGGCTATCGACCGGGGGCTTGCCGCTTTAAAAAACAAAAATTTAATTATTACCGATGTGGAAATGGTCCGGGCG
GGAATTACCGGTTATGCCGGCGAGGTAGCCTGCGCGATTCGCGAGGAAGCGGTTAAAAGAAAAGCTTTAGAAAATAAAGT
TACCCGGGCTTATCAGGCGATGATGGAGCTAAAAGAGCGAATGGATGGAGCGGTTATAGCAATTGGTAATGCCCCAACAG
CTCTTTTAGCGGTGATTGAACTCATAAAGACCGGGGTAGAGCCGGCGCTGGTGGTGGGAGTGCCGGTGGGCTTTGTTGGA
GCAAAAGAAAGTAAGGAACTTTTGCTGAACTGTGATGTGCCGTATATCACGTTACTGGGTACTAAAGGGGGTAGTACCAT
TGCGGCAGCAATAGTTAATGCTTTAATTAAATTATCCAGGACCGGAGGGAAATAA

Upstream 100 bases:

>100_bases
GACCAGTTAAAAGCCCAGTATCCCGATTTAAAGATTACGGTTTATAAACCTTTAGGTGAAAAAGAACAATTTATTGAATT
TTTAGCGGCGGTGTTGGCCA

Downstream 100 bases:

>100_bases
AGTGAAGGTGTTAATTACCGGTGGGGTGCGTTCGGGCAAAAGTAGTTTTGCGGAAAAGTTAGCGACCTCTTTCGGGGAAA
AAGTGGTATATGTGGCTACC

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MNYEFLINPREIEQKSFAIIESLTGLGNTPEDQVIKRAIHASGDPEIRKDFRFHPAAIDRGLAALKNKNLIITDVEMVRA
GITGYAGEVACAIREEAVKRKALENKVTRAYQAMMELKERMDGAVIAIGNAPTALLAVIELIKTGVEPALVVGVPVGFVG
AKESKELLLNCDVPYITLLGTKGGSTIAAAIVNALIKLSRTGGK

Sequences:

>Translated_204_residues
MNYEFLINPREIEQKSFAIIESLTGLGNTPEDQVIKRAIHASGDPEIRKDFRFHPAAIDRGLAALKNKNLIITDVEMVRA
GITGYAGEVACAIREEAVKRKALENKVTRAYQAMMELKERMDGAVIAIGNAPTALLAVIELIKTGVEPALVVGVPVGFVG
AKESKELLLNCDVPYITLLGTKGGSTIAAAIVNALIKLSRTGGK
>Mature_204_residues
MNYEFLINPREIEQKSFAIIESLTGLGNTPEDQVIKRAIHASGDPEIRKDFRFHPAAIDRGLAALKNKNLIITDVEMVRA
GITGYAGEVACAIREEAVKRKALENKVTRAYQAMMELKERMDGAVIAIGNAPTALLAVIELIKTGVEPALVVGVPVGFVG
AKESKELLLNCDVPYITLLGTKGGSTIAAAIVNALIKLSRTGGK

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: NA

Molecular weight: Translated: 21882; Mature: 21882

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYEFLINPREIEQKSFAIIESLTGLGNTPEDQVIKRAIHASGDPEIRKDFRFHPAAIDR
CCCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHH
GLAALKNKNLIITDVEMVRAGITGYAGEVACAIREEAVKRKALENKVTRAYQAMMELKER
HHHHHCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDGAVIAIGNAPTALLAVIELIKTGVEPALVVGVPVGFVGAKESKELLLNCDVPYITLLG
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEEE
TKGGSTIAAAIVNALIKLSRTGGK
CCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNYEFLINPREIEQKSFAIIESLTGLGNTPEDQVIKRAIHASGDPEIRKDFRFHPAAIDR
CCCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHH
GLAALKNKNLIITDVEMVRAGITGYAGEVACAIREEAVKRKALENKVTRAYQAMMELKER
HHHHHCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDGAVIAIGNAPTALLAVIELIKTGVEPALVVGVPVGFVGAKESKELLLNCDVPYITLLG
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEEE
TKGGSTIAAAIVNALIKLSRTGGK
CCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]