Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 78043933

GI number: 78043933

Start: 175285

End: 176172

Strand: Direct

Name: aroB [H]

Synonym: CHY_0211

Alternate gene names: 78043933

Gene position: 175285-176172 (Clockwise)

Preceding gene: 78043729

Following gene: 78042785

Centisome position: 7.3

GC content: 43.81

Gene sequence:

>888_bases
ATGCCAGCAGTGATTGATATCGGAACAAATTCGGTACGGGTTTTAGTTGGTTCTTTTAACAATGGTAAATTTTACGAAGA
GTACCGGGACTTGAGGACCACCCGTATTGGCCAAGGGATAAACTCGGGGTATTTAAAAGAAGAGGCGATGGAGCGAACCT
TGAAGGTGGTTGTAGAATTTGTTGAAAAAGCCCGGGAATTTACCGATGAGATAGTGATTTTTGCCACCAGTGCGGTGCGC
GATGCTAAAAATCAAAGGGAGTTTGTGGATAAAATAAAAAGCGCAACCGGTATAACCCTTGAGGTTTTAACGGGCGAGGA
GGAAGCTTATTATTCTTATCAGGGAGTAAAGCTATCATTACCTTATTTAAACGAACCTGCGGTTATCGATTTGGGTGGCG
GGAGTATTGAGTTTATCTGGCAGGAACGGGGGAAAACCTTATTTCAAAGCGTCCCAGTTGGGGCAGTAAGATTAATGGAG
GCTGTAGACAAGGAGGGTTTGCTGAAACTTTTACGGGATTTTGTCGGGAAAATAACTCCCTATTTTCATGAACCGGTGGT
GGCGGTTGGTGGTACCGCTACAACTTTAGCGGCAATTGACCTGAAGTTAGAAAAATACGATCCCCGCAAAGTGGAGGGGC
ATGCTATTGAATTACCGCGGCTTAGAGAAATCCATAATTATTTAGAAAGTTTACCCTTACCCGAACGCCAAAAGGTACCG
GGACTTTTACCCGAGCGAGCAGATATTATCGTTTATGGCTGTAAAATATTAATTGAAGTTCTAACCACCGCCCGGCTTTC
CGGGCTAATTGTGGGAGAAGGGGACCTGCTTTTAGGAAAACTTAAAGAAATGACGGTGTCGAAAGAAAATAAAGGGCCAA
AACTTTAA

Upstream 100 bases:

>100_bases
AGGCTAAAAAATAACTCGCACTTTGAAACTCGCGCCAGGGAGATGGGGTTTGTAAAACCTGGAGAAAAAGTAATTGTAAT
TGAAAAGAAGGGAAATAAAG

Downstream 100 bases:

>100_bases
AATGACAAAAATTTCCTCCTTGCAAGGCTATAATAACCATTAGAAGCCTTGGAAAAAGGAGGATTTTTTTTGGAAACCAA
GATCTATCCCTTTGCCCGTA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPAVIDIGTNSVRVLVGSFNNGKFYEEYRDLRTTRIGQGINSGYLKEEAMERTLKVVVEFVEKAREFTDEIVIFATSAVR
DAKNQREFVDKIKSATGITLEVLTGEEEAYYSYQGVKLSLPYLNEPAVIDLGGGSIEFIWQERGKTLFQSVPVGAVRLME
AVDKEGLLKLLRDFVGKITPYFHEPVVAVGGTATTLAAIDLKLEKYDPRKVEGHAIELPRLREIHNYLESLPLPERQKVP
GLLPERADIIVYGCKILIEVLTTARLSGLIVGEGDLLLGKLKEMTVSKENKGPKL

Sequences:

>Translated_295_residues
MPAVIDIGTNSVRVLVGSFNNGKFYEEYRDLRTTRIGQGINSGYLKEEAMERTLKVVVEFVEKAREFTDEIVIFATSAVR
DAKNQREFVDKIKSATGITLEVLTGEEEAYYSYQGVKLSLPYLNEPAVIDLGGGSIEFIWQERGKTLFQSVPVGAVRLME
AVDKEGLLKLLRDFVGKITPYFHEPVVAVGGTATTLAAIDLKLEKYDPRKVEGHAIELPRLREIHNYLESLPLPERQKVP
GLLPERADIIVYGCKILIEVLTTARLSGLIVGEGDLLLGKLKEMTVSKENKGPKL
>Mature_294_residues
PAVIDIGTNSVRVLVGSFNNGKFYEEYRDLRTTRIGQGINSGYLKEEAMERTLKVVVEFVEKAREFTDEIVIFATSAVRD
AKNQREFVDKIKSATGITLEVLTGEEEAYYSYQGVKLSLPYLNEPAVIDLGGGSIEFIWQERGKTLFQSVPVGAVRLMEA
VDKEGLLKLLRDFVGKITPYFHEPVVAVGGTATTLAAIDLKLEKYDPRKVEGHAIELPRLREIHNYLESLPLPERQKVPG
LLPERADIIVYGCKILIEVLTTARLSGLIVGEGDLLLGKLKEMTVSKENKGPKL

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=293, Percent_Identity=28.3276450511945, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788848, Length=302, Percent_Identity=27.1523178807947, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32840; Mature: 32708

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVIDIGTNSVRVLVGSFNNGKFYEEYRDLRTTRIGQGINSGYLKEEAMERTLKVVVEF
CCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VEKAREFTDEIVIFATSAVRDAKNQREFVDKIKSATGITLEVLTGEEEAYYSYQGVKLSL
HHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHEEEECCEEEEC
PYLNEPAVIDLGGGSIEFIWQERGKTLFQSVPVGAVRLMEAVDKEGLLKLLRDFVGKITP
CCCCCCCEEEECCCCEEEEEHHCCHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCC
YFHEPVVAVGGTATTLAAIDLKLEKYDPRKVEGHAIELPRLREIHNYLESLPLPERQKVP
HHCCCEEEECCCHHEEEEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCC
GLLPERADIIVYGCKILIEVLTTARLSGLIVGEGDLLLGKLKEMTVSKENKGPKL
CCCCCCCCEEEHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PAVIDIGTNSVRVLVGSFNNGKFYEEYRDLRTTRIGQGINSGYLKEEAMERTLKVVVEF
CEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VEKAREFTDEIVIFATSAVRDAKNQREFVDKIKSATGITLEVLTGEEEAYYSYQGVKLSL
HHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHEEEECCEEEEC
PYLNEPAVIDLGGGSIEFIWQERGKTLFQSVPVGAVRLMEAVDKEGLLKLLRDFVGKITP
CCCCCCCEEEECCCCEEEEEHHCCHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCC
YFHEPVVAVGGTATTLAAIDLKLEKYDPRKVEGHAIELPRLREIHNYLESLPLPERQKVP
HHCCCEEEECCCHHEEEEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCC
GLLPERADIIVYGCKILIEVLTTARLSGLIVGEGDLLLGKLKEMTVSKENKGPKL
CCCCCCCCEEEHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]