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The map label for this gene is grdD [H]

Identifier: 78043649

GI number: 78043649

Start: 2144794

End: 2145939

Strand: Direct

Name: grdD [H]

Synonym: CHY_2395

Alternate gene names: 78043649

Gene position: 2144794-2145939 (Clockwise)

Preceding gene: 78044225

Following gene: 78043804

Centisome position: 89.31

GC content: 47.12

Gene sequence:

>1146_bases
ATGGAGCAGGTAAAAAGATTAATTGCGGAAGTGTTAAATGAAGCAGCGGATGTTATTGCCACCGGACGGGCTCTTAAAAA
CATCCGGGTAGGTATCACCCTTCTGGGCAGTGAACACGGTGTGCTTGAAGTGTTAAAAGGTGCCGAGATGGCCGCCCAAA
ACCTTCCTAACGTTGAAGTCGTAGTAATTGGTCCGGAAGATGTCGAAACCAGGCTCACTAAAGTCGTTGTCACCGATGAA
AAAGAAGGCCACCGGGTAATGGAAAAGATGTTAGACTCCGGTGAATTAAATGCGGCCGTTACCATGCATTACAACTTCCC
TATCGGCACCTCTACTGTAGGTTTGGTAGTAACCCCCGCTCAGGGCCGGAAAATGTTTATTGCCACTACCACCGGTACCT
CTTCCCCCGACCGGGTGGAAGGAATGGTTAAAAACGCTATTTACGGCATTGCCGCTGCCAAAGCTTACGGAATTAAAAAT
CCTAAAGTTGGTATCTTAAATGTTGACGGCGCCCGGCAGGTAGAAAGAATTTTAAAAGAACTCCAAAGTCGCGGCTACCC
AATTGATTTTAGCGAATCAAAGCGTTCCGACGGCGGTGTAGTAATGCGGGGTAACGACTTACTTGCCGGTACTCCCGACG
TCATGATTTGCGATAGCTTAACCGGCAACCTCTTAATTAAAATCTTCTCCGCCTACACCACCGGTGGAAGTTACGAGGCT
TTAGGCTACGGCTACGGTCCGGGAATTGGAGAAGGCTTTAACAAAATAATTAATATCATTTCCCGGGCCTCGGGCGCCCC
GGTAATTGCCGGTGCTATTGAATACGCCGCCGCCATGGCCCAGGGTAGACTTGTAGAAGTTGCACAGGCAGAAATCGCAG
CTGCTAAAAACGCAGGGCTTCTTGAATTGGTAAAACCTTTAGAGAAAAAAGAAACAGTCGAAGAAGTAAAAATGCCCCCG
AAAAAACCGGTAGACAAAGAAATTGCCGGAATTGATGTTTTAGAATTGGAAAATGCCCAGAAGCTTTTATGGAAACACGG
TATTTATGCCGAAACCGGCATGGGTTGCACCGGTCCCATTATTCTTGTAGCTCCGGACGACTTAAGTCAGGCCCTTAAAG
TCTTAAAGGAAAATAAAGTATTGTAG

Upstream 100 bases:

>100_bases
AGGAAACTACCGGCCTTACAAAAGAAGCCGTTCGGGAAATGGTTGCCGAGTACTTAAGGGAAATGGCCAAAGGCCTTCTT
TCCTAAGGGGGTACAAATAA

Downstream 100 bases:

>100_bases
GGTCCGGTTTAGAGGTTTGAGGTTGGCAGTAAAACCCCTGCAGGCATAAGATGCAGTCTTAAGCCCGCCCTACATTAAAC
AAAAAGCCGCAGAGGTTTTG

Product: glycine reductase complex, protein D

Products: NA

Alternate protein names: Protein PC alpha [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MEQVKRLIAEVLNEAADVIATGRALKNIRVGITLLGSEHGVLEVLKGAEMAAQNLPNVEVVVIGPEDVETRLTKVVVTDE
KEGHRVMEKMLDSGELNAAVTMHYNFPIGTSTVGLVVTPAQGRKMFIATTTGTSSPDRVEGMVKNAIYGIAAAKAYGIKN
PKVGILNVDGARQVERILKELQSRGYPIDFSESKRSDGGVVMRGNDLLAGTPDVMICDSLTGNLLIKIFSAYTTGGSYEA
LGYGYGPGIGEGFNKIINIISRASGAPVIAGAIEYAAAMAQGRLVEVAQAEIAAAKNAGLLELVKPLEKKETVEEVKMPP
KKPVDKEIAGIDVLELENAQKLLWKHGIYAETGMGCTGPIILVAPDDLSQALKVLKENKVL

Sequences:

>Translated_381_residues
MEQVKRLIAEVLNEAADVIATGRALKNIRVGITLLGSEHGVLEVLKGAEMAAQNLPNVEVVVIGPEDVETRLTKVVVTDE
KEGHRVMEKMLDSGELNAAVTMHYNFPIGTSTVGLVVTPAQGRKMFIATTTGTSSPDRVEGMVKNAIYGIAAAKAYGIKN
PKVGILNVDGARQVERILKELQSRGYPIDFSESKRSDGGVVMRGNDLLAGTPDVMICDSLTGNLLIKIFSAYTTGGSYEA
LGYGYGPGIGEGFNKIINIISRASGAPVIAGAIEYAAAMAQGRLVEVAQAEIAAAKNAGLLELVKPLEKKETVEEVKMPP
KKPVDKEIAGIDVLELENAQKLLWKHGIYAETGMGCTGPIILVAPDDLSQALKVLKENKVL
>Mature_381_residues
MEQVKRLIAEVLNEAADVIATGRALKNIRVGITLLGSEHGVLEVLKGAEMAAQNLPNVEVVVIGPEDVETRLTKVVVTDE
KEGHRVMEKMLDSGELNAAVTMHYNFPIGTSTVGLVVTPAQGRKMFIATTTGTSSPDRVEGMVKNAIYGIAAAKAYGIKN
PKVGILNVDGARQVERILKELQSRGYPIDFSESKRSDGGVVMRGNDLLAGTPDVMICDSLTGNLLIKIFSAYTTGGSYEA
LGYGYGPGIGEGFNKIINIISRASGAPVIAGAIEYAAAMAQGRLVEVAQAEIAAAKNAGLLELVKPLEKKETVEEVKMPP
KKPVDKEIAGIDVLELENAQKLLWKHGIYAETGMGCTGPIILVAPDDLSQALKVLKENKVL

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: COG0416

COG function: function code I; Fatty acid/phospholipid biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003664
- InterPro:   IPR012116 [H]

Pfam domain/function: PF02504 FA_synthesis [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 40531; Mature: 40531

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVKRLIAEVLNEAADVIATGRALKNIRVGITLLGSEHGVLEVLKGAEMAAQNLPNVEV
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VVIGPEDVETRLTKVVVTDEKEGHRVMEKMLDSGELNAAVTMHYNFPIGTSTVGLVVTPA
EEECCCCHHCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECC
QGRKMFIATTTGTSSPDRVEGMVKNAIYGIAAAKAYGIKNPKVGILNVDGARQVERILKE
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHH
LQSRGYPIDFSESKRSDGGVVMRGNDLLAGTPDVMICDSLTGNLLIKIFSAYTTGGSYEA
HHHCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCEE
LGYGYGPGIGEGFNKIINIISRASGAPVIAGAIEYAAAMAQGRLVEVAQAEIAAAKNAGL
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCH
LELVKPLEKKETVEEVKMPPKKPVDKEIAGIDVLELENAQKLLWKHGIYAETGMGCTGPI
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCHHHHHHHCCCCEECCCCCCCCE
ILVAPDDLSQALKVLKENKVL
EEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEQVKRLIAEVLNEAADVIATGRALKNIRVGITLLGSEHGVLEVLKGAEMAAQNLPNVEV
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VVIGPEDVETRLTKVVVTDEKEGHRVMEKMLDSGELNAAVTMHYNFPIGTSTVGLVVTPA
EEECCCCHHCEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECC
QGRKMFIATTTGTSSPDRVEGMVKNAIYGIAAAKAYGIKNPKVGILNVDGARQVERILKE
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHH
LQSRGYPIDFSESKRSDGGVVMRGNDLLAGTPDVMICDSLTGNLLIKIFSAYTTGGSYEA
HHHCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCEE
LGYGYGPGIGEGFNKIINIISRASGAPVIAGAIEYAAAMAQGRLVEVAQAEIAAAKNAGL
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCH
LELVKPLEKKETVEEVKMPPKKPVDKEIAGIDVLELENAQKLLWKHGIYAETGMGCTGPI
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCHHHHHHHCCCCEECCCCCCCCE
ILVAPDDLSQALKVLKENKVL
EEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11737196; 1587286 [H]