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The map label for this gene is sucC [H]

Identifier: 78043370

GI number: 78043370

Start: 805084

End: 806205

Strand: Direct

Name: sucC [H]

Synonym: CHY_0912

Alternate gene names: 78043370

Gene position: 805084-806205 (Clockwise)

Preceding gene: 78044725

Following gene: 78042669

Centisome position: 33.52

GC content: 46.26

Gene sequence:

>1122_bases
GTGAAACTTTTTGAATACCAGGTAAAGAAAATTATGAGGGAGTTCGGGATTTTAGTTCCCCGGGGTGAGGTTTTTTTTGA
TTTAGAGCAGGCCAAAAACCATCTGGAAAAAGTTGGCGAAGGAGTAATCAAAGCGCAGGTATTAACCGGTGGCAGGGGTA
AAGCCGGGGGGGTAAAAATCTTTTCCAATCCGGCAGAAGGTTTTGAACTGGCGGAAGCTATCTTGAAGATGACCATTAAG
GGAGAGAAAGTTCAGGCAATCTTAATTGAAGAGAAAATTCCCATTGAGCAGGAGCTTTATTTATCAATTTTTGTGGATGG
ACGGATTAAAAAGCCGGTAGTGATTGCTTCAAAAGCGGGTGGCGTGGACATTGAAGAAGTACCGGAAGAGGAAATTTTAA
AACTTCCCGTAGACCCGTTAATTGGAGTTAGAAATTATCACGGAAACCTGGTGGCGCAAAAGCTGGGACTTACGGGAGAT
TTAGGAAAACAGCTTGCTACTTTGTTAATTAACTTATACCGCATTTTTGAAACTTACCAGGCGGAGCTTGTGGAGATAAA
TCCCCTGGTGATTTCCCGGGAAAAGCTTATCGCCGCCGATGGCAAGATGACGGTGGATGATGATGCGCGTTTTCGCTGGC
CCGCGGACCTTCCCTTTAACGAAGAAAAAACCCCGTTGGAAAAAAGAGCCGAGGAAATTGGCGTATCCTTTGTCGAACTG
GATGGGGATATAGCGGTGATGGCCAATGGTGCGGGAATTACCATGGCTACTTTGGACTTAATTGCCTATTTTGGCGGAAG
GCCAAAGAATTTTATGGATGCCGGTGGTGGGGCTAACGCCGAGCAAATGGCCAAAGCGCTGGACCTTTTAATCTCCACCA
ATCCCAAGGCAATTTTAATAAATATTTTTGGCGGTATAACCCGTTGTGATGAGGTGGCAAAAGCTTACTTAACGGTGAAA
CAGGAGAGGGAAATAACGGTGCCGGTGGTGATTCGCCTGGTGGGAACCAATGAAGATATCGGGGTAAAAATGCTTCAGGA
GGCGGGAGTGGAAAGCTTTTCTTCCCTGCGGGAAGCGGTGATTAAAGCGGTGGAGCTTGCCAAAGTTGGGGGGGATAATT
AG

Upstream 100 bases:

>100_bases
AATATATATAATATTAGTAAAAAAGATTTAAATTGTATAGTGTATACAAAGTTGATTTTTTATTTTTCAACATAAATTTA
TTCAGCAAGGAGGGAAGGTA

Downstream 100 bases:

>100_bases
TGGCTATCATTATTACCGAAGAAACGCGGATAGTTGTCCAGGGGATTACGGGTAATCAGGGACGGTTTCATACCGGGAAA
ATGCTGGAATACGGGAGCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKLFEYQVKKIMREFGILVPRGEVFFDLEQAKNHLEKVGEGVIKAQVLTGGRGKAGGVKIFSNPAEGFELAEAILKMTIK
GEKVQAILIEEKIPIEQELYLSIFVDGRIKKPVVIASKAGGVDIEEVPEEEILKLPVDPLIGVRNYHGNLVAQKLGLTGD
LGKQLATLLINLYRIFETYQAELVEINPLVISREKLIAADGKMTVDDDARFRWPADLPFNEEKTPLEKRAEEIGVSFVEL
DGDIAVMANGAGITMATLDLIAYFGGRPKNFMDAGGGANAEQMAKALDLLISTNPKAILINIFGGITRCDEVAKAYLTVK
QEREITVPVVIRLVGTNEDIGVKMLQEAGVESFSSLREAVIKAVELAKVGGDN

Sequences:

>Translated_373_residues
MKLFEYQVKKIMREFGILVPRGEVFFDLEQAKNHLEKVGEGVIKAQVLTGGRGKAGGVKIFSNPAEGFELAEAILKMTIK
GEKVQAILIEEKIPIEQELYLSIFVDGRIKKPVVIASKAGGVDIEEVPEEEILKLPVDPLIGVRNYHGNLVAQKLGLTGD
LGKQLATLLINLYRIFETYQAELVEINPLVISREKLIAADGKMTVDDDARFRWPADLPFNEEKTPLEKRAEEIGVSFVEL
DGDIAVMANGAGITMATLDLIAYFGGRPKNFMDAGGGANAEQMAKALDLLISTNPKAILINIFGGITRCDEVAKAYLTVK
QEREITVPVVIRLVGTNEDIGVKMLQEAGVESFSSLREAVIKAVELAKVGGDN
>Mature_373_residues
MKLFEYQVKKIMREFGILVPRGEVFFDLEQAKNHLEKVGEGVIKAQVLTGGRGKAGGVKIFSNPAEGFELAEAILKMTIK
GEKVQAILIEEKIPIEQELYLSIFVDGRIKKPVVIASKAGGVDIEEVPEEEILKLPVDPLIGVRNYHGNLVAQKLGLTGD
LGKQLATLLINLYRIFETYQAELVEINPLVISREKLIAADGKMTVDDDARFRWPADLPFNEEKTPLEKRAEEIGVSFVEL
DGDIAVMANGAGITMATLDLIAYFGGRPKNFMDAGGGANAEQMAKALDLLISTNPKAILINIFGGITRCDEVAKAYLTVK
QEREITVPVVIRLVGTNEDIGVKMLQEAGVESFSSLREAVIKAVELAKVGGDN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=37.0757180156658, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI11321583, Length=395, Percent_Identity=34.9367088607595, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=37.7410468319559, Blast_Score=206, Evalue=4e-53,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=38.60103626943, Blast_Score=234, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17567829, Length=360, Percent_Identity=36.9444444444444, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=34.1836734693878, Blast_Score=199, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=36.8686868686869, Blast_Score=231, Evalue=2e-61,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=36.5482233502538, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=33.8501291989664, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=33.8501291989664, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=33.7628865979381, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=33.7628865979381, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40734; Mature: 40734

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFEYQVKKIMREFGILVPRGEVFFDLEQAKNHLEKVGEGVIKAQVLTGGRGKAGGVKI
CCHHHHHHHHHHHHHCCEEECCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEE
FSNPAEGFELAEAILKMTIKGEKVQAILIEEKIPIEQELYLSIFVDGRIKKPVVIASKAG
ECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEECCC
GVDIEEVPEEEILKLPVDPLIGVRNYHGNLVAQKLGLTGDLGKQLATLLINLYRIFETYQ
CCCHHHCCHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AELVEINPLVISREKLIAADGKMTVDDDARFRWPADLPFNEEKTPLEKRAEEIGVSFVEL
HHEEEECCEEEECCCEEECCCCEEECCCCCEECCCCCCCCCCCCCHHHHHHHHCCEEEEE
DGDIAVMANGAGITMATLDLIAYFGGRPKNFMDAGGGANAEQMAKALDLLISTNPKAILI
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCEEEE
NIFGGITRCDEVAKAYLTVKQEREITVPVVIRLVGTNEDIGVKMLQEAGVESFSSLREAV
EECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHH
IKAVELAKVGGDN
HHHHHHHHCCCCC
>Mature Secondary Structure
MKLFEYQVKKIMREFGILVPRGEVFFDLEQAKNHLEKVGEGVIKAQVLTGGRGKAGGVKI
CCHHHHHHHHHHHHHCCEEECCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEE
FSNPAEGFELAEAILKMTIKGEKVQAILIEEKIPIEQELYLSIFVDGRIKKPVVIASKAG
ECCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCCEEEEECCC
GVDIEEVPEEEILKLPVDPLIGVRNYHGNLVAQKLGLTGDLGKQLATLLINLYRIFETYQ
CCCHHHCCHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AELVEINPLVISREKLIAADGKMTVDDDARFRWPADLPFNEEKTPLEKRAEEIGVSFVEL
HHEEEECCEEEECCCEEECCCCEEECCCCCEECCCCCCCCCCCCCHHHHHHHHCCEEEEE
DGDIAVMANGAGITMATLDLIAYFGGRPKNFMDAGGGANAEQMAKALDLLISTNPKAILI
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHCCCCCCEEEE
NIFGGITRCDEVAKAYLTVKQEREITVPVVIRLVGTNEDIGVKMLQEAGVESFSSLREAV
EECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHH
IKAVELAKVGGDN
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA