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The map label for this gene is sucD [H]

Identifier: 78042669

GI number: 78042669

Start: 806205

End: 807074

Strand: Direct

Name: sucD [H]

Synonym: CHY_0913

Alternate gene names: 78042669

Gene position: 806205-807074 (Clockwise)

Preceding gene: 78043370

Following gene: 78043708

Centisome position: 33.57

GC content: 50.34

Gene sequence:

>870_bases
GTGGCTATCATTATTACCGAAGAAACGCGGATAGTTGTCCAGGGGATTACGGGTAATCAGGGACGGTTTCATACCGGGAA
AATGCTGGAATACGGGAGCAAAGTTGTGGCCGGTGTAAGTCCCGGTAAAGGGGGGACAGAGGTTTTAGGGGTGCCGGTTT
TTAATACCGTTTTAGATGCGGTAAAAAATACCGGAGCCAATACCTCGATATTGTTTATCCCTGCGCCCTTTGTTTTGGAT
GCTGCTCTGGAAGCAATGGAAGCGGGGATTAAAACCATTGTTATTATTAGCGAGCATGTACCCTTACACGATGCTCTGAA
AATTATGCGGGTGGCAGAAGCCTACGGAGTTACCGTTGTTGGTCCAAACACTTTTGGAGTTATCTCCCCGGGAATTGCCA
AAGTTGGGATTATGCCCAATACCATTTACCAGAAAGGTCCGGTTGGGATCGTGGCCCGAAGCGGTACTTTAAGCTACCAG
ATTGCTTATGAATTAACCAGGGCGGGTTTGGGTCAATCGACGGTCGTGGGGCTGGGGGGAGATCGAATAGTGGGACTTTC
CCTGGCCGAAGTGATCTTAAGCCTTGCCCGGGATGAGGAAACCCAGGGAATTGTGGTGGTGGGTGAAATTGGCGGTACAG
CGGAAGAAGAAGCGGCGGAGGTCATTCGCCACATTAATAAGCCGGTAGTGGCTTTTATTGCTGGAAAAACAGCGCCTCCG
GGAAAAAGAATGGGGCATGCCGGGGCTATTATTGAGAGGGGGCGGGGCACTTACCAGAGTAAAATTGATGCCCTCTGGAA
TGCCGGCGCTTTAATTGCGGAAGTGCCCTGGGAAGTGCCGGTGTTAATGAAATCAGCTTTGGTTAAGTAG

Upstream 100 bases:

>100_bases
GGGTAAAAATGCTTCAGGAGGCGGGAGTGGAAAGCTTTTCTTCCCTGCGGGAAGCGGTGATTAAAGCGGTGGAGCTTGCC
AAAGTTGGGGGGGATAATTA

Downstream 100 bases:

>100_bases
GAGGGTGTTGGGGATGGCTGTTGAGGAGAAAAAAGTGGTTTTAGACTCGGGGATCGAGGTCAAAACCGTTTACGGCCCCG
ATGATCTTGCAGGCTTTAAC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 2; SCS-alpha 2 [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAIIITEETRIVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDAVKNTGANTSILFIPAPFVLD
AALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVVGPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSYQ
IAYELTRAGLGQSTVVGLGGDRIVGLSLAEVILSLARDEETQGIVVVGEIGGTAEEEAAEVIRHINKPVVAFIAGKTAPP
GKRMGHAGAIIERGRGTYQSKIDALWNAGALIAEVPWEVPVLMKSALVK

Sequences:

>Translated_289_residues
MAIIITEETRIVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDAVKNTGANTSILFIPAPFVLD
AALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVVGPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSYQ
IAYELTRAGLGQSTVVGLGGDRIVGLSLAEVILSLARDEETQGIVVVGEIGGTAEEEAAEVIRHINKPVVAFIAGKTAPP
GKRMGHAGAIIERGRGTYQSKIDALWNAGALIAEVPWEVPVLMKSALVK
>Mature_288_residues
AIIITEETRIVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDAVKNTGANTSILFIPAPFVLDA
ALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVVGPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSYQI
AYELTRAGLGQSTVVGLGGDRIVGLSLAEVILSLARDEETQGIVVVGEIGGTAEEEAAEVIRHINKPVVAFIAGKTAPPG
KRMGHAGAIIERGRGTYQSKIDALWNAGALIAEVPWEVPVLMKSALVK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=283, Percent_Identity=46.9964664310954, Blast_Score=219, Evalue=2e-57,
Organism=Homo sapiens, GI38569423, Length=244, Percent_Identity=33.1967213114754, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38569421, Length=244, Percent_Identity=33.1967213114754, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786949, Length=270, Percent_Identity=52.2222222222222, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17550194, Length=290, Percent_Identity=46.2068965517241, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=45.5479452054795, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17557344, Length=246, Percent_Identity=31.3008130081301, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=246, Percent_Identity=31.3008130081301, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=284, Percent_Identity=41.9014084507042, Blast_Score=215, Evalue=7e-57,
Organism=Drosophila melanogaster, GI21356559, Length=281, Percent_Identity=45.1957295373665, Blast_Score=247, Evalue=5e-66,
Organism=Drosophila melanogaster, GI28574296, Length=278, Percent_Identity=45.6834532374101, Blast_Score=221, Evalue=6e-58,
Organism=Drosophila melanogaster, GI281363477, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281363475, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281363473, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30107; Mature: 29975

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIITEETRIVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDA
CEEEEECCCEEEEEECCCCCCCEECCHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHH
VKNTGANTSILFIPAPFVLDAALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVV
HHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEE
GPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSYQIAYELTRAGLGQSTVVGLGG
CCCCCCEECCCCEEECCCCCHHCCCCCEEEEEECCCEEEEEEEEHHHCCCCCCEEEECCC
DRIVGLSLAEVILSLARDEETQGIVVVGEIGGTAEEEAAEVIRHINKPVVAFIAGKTAPP
CEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
GKRMGHAGAIIERGRGTYQSKIDALWNAGALIAEVPWEVPVLMKSALVK
CCCCCCCCHHEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
AIIITEETRIVVQGITGNQGRFHTGKMLEYGSKVVAGVSPGKGGTEVLGVPVFNTVLDA
EEEEECCCEEEEEECCCCCCCEECCHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHH
VKNTGANTSILFIPAPFVLDAALEAMEAGIKTIVIISEHVPLHDALKIMRVAEAYGVTVV
HHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEE
GPNTFGVISPGIAKVGIMPNTIYQKGPVGIVARSGTLSYQIAYELTRAGLGQSTVVGLGG
CCCCCCEECCCCEEECCCCCHHCCCCCEEEEEECCCEEEEEEEEHHHCCCCCCEEEECCC
DRIVGLSLAEVILSLARDEETQGIVVVGEIGGTAEEEAAEVIRHINKPVVAFIAGKTAPP
CEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
GKRMGHAGAIIERGRGTYQSKIDALWNAGALIAEVPWEVPVLMKSALVK
CCCCCCCCHHEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]