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The map label for this gene is trxA [H]

Identifier: 78043049

GI number: 78043049

Start: 2139648

End: 2139977

Strand: Direct

Name: trxA [H]

Synonym: CHY_2390

Alternate gene names: 78043049

Gene position: 2139648-2139977 (Clockwise)

Preceding gene: 78044856

Following gene: 78043612

Centisome position: 89.1

GC content: 43.03

Gene sequence:

>330_bases
ATGGCGGGAAACATAATTGAGCTAAACAAAGACAATTTTGAAGAAGAAGTTTTAAAAAGCGAGCTTCCGGTTCTGGTGGA
CTTCTGGGGTCCCCGGTGCGTACCCTGCATGGGTTTAATGCCGGTAGTAGAAGAATTGGCCGAAATCTATGCGGGTAAAA
TGAAGTTTACCAAATTAAACACTGCCGAAAACCGGAGGCTTGCCATTCAGCTTAAAGTTATGAGCCTTCCTACTTTCCAG
TTTTATAAAAACGGCGAACTTGTAGACCAGCTACAAGGTAATTTTGGCCGCGAAGAAATTGAAGAAAAAATTCGGGCCAT
TATCGGCTAA

Upstream 100 bases:

>100_bases
TGTTACGGCAGGTAGTAACTGCCGCTGCTGACGGTGCTATTGCTGCTTACCATGCGGAAAAATATCTTGAAGAATGTACC
GAGTAAAGGAGGTGATAAAC

Downstream 100 bases:

>100_bases
GGAGGGATAAAATGCGGCTTACCCTTGGGAAAATTAACATTAAAGGGCTGGAATTTGGCCCCAGTACCCGGGTCGAAAAC
GGAGTTCTTTACGTTAATAA

Product: putative thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MAGNIIELNKDNFEEEVLKSELPVLVDFWGPRCVPCMGLMPVVEELAEIYAGKMKFTKLNTAENRRLAIQLKVMSLPTFQ
FYKNGELVDQLQGNFGREEIEEKIRAIIG

Sequences:

>Translated_109_residues
MAGNIIELNKDNFEEEVLKSELPVLVDFWGPRCVPCMGLMPVVEELAEIYAGKMKFTKLNTAENRRLAIQLKVMSLPTFQ
FYKNGELVDQLQGNFGREEIEEKIRAIIG
>Mature_108_residues
AGNIIELNKDNFEEEVLKSELPVLVDFWGPRCVPCMGLMPVVEELAEIYAGKMKFTKLNTAENRRLAIQLKVMSLPTFQF
YKNGELVDQLQGNFGREEIEEKIRAIIG

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=98, Percent_Identity=33.6734693877551, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788936, Length=79, Percent_Identity=41.7721518987342, Blast_Score=84, Evalue=2e-18,
Organism=Escherichia coli, GI87082331, Length=106, Percent_Identity=34.9056603773585, Blast_Score=82, Evalue=7e-18,
Organism=Escherichia coli, GI87081747, Length=106, Percent_Identity=33.9622641509434, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212646193, Length=99, Percent_Identity=30.3030303030303, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 12449; Mature: 12318

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNIIELNKDNFEEEVLKSELPVLVDFWGPRCVPCMGLMPVVEELAEIYAGKMKFTKLN
CCCCEEEECCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEC
TAENRRLAIQLKVMSLPTFQFYKNGELVDQLQGNFGREEIEEKIRAIIG
CCCCCEEEEEEEECCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AGNIIELNKDNFEEEVLKSELPVLVDFWGPRCVPCMGLMPVVEELAEIYAGKMKFTKLN
CCCEEEECCCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEC
TAENRRLAIQLKVMSLPTFQFYKNGELVDQLQGNFGREEIEEKIRAIIG
CCCCCEEEEEEEECCCCCEEECCCCCHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8223622; 1995593 [H]