Click here to switch to the map view.

The map label for this gene is trxB2 [H]

Identifier: 78044856

GI number: 78044856

Start: 2138710

End: 2139633

Strand: Direct

Name: trxB2 [H]

Synonym: CHY_2389

Alternate gene names: 78044856

Gene position: 2138710-2139633 (Clockwise)

Preceding gene: 78043499

Following gene: 78043049

Centisome position: 89.06

GC content: 49.78

Gene sequence:

>924_bases
ATGGAAAGATACGATGTAATCATCATCGGCGCCGGTCCTGCTGGACTTTCCGCAGCTCTTTACAGCGCCCGGAGTAAGCT
TTCCACCCTTTATATTGAAAAGCTTTCCACCGGCGGACAGGCTGCCACTACCGATGAAATTGAAAATTATCCGGGATTTG
CCCATGGGATTTCCGGCCCGGAACTTACCGCCCAAATGGAGGAACAAGCAAAGCGTTTTGGTGCCAAAAAACTTTTGGCC
GAAGTAAAGGGGATTGAGCTTGCGGGGGCTGACCGGATCGTCAAAACCACCAAAGGTAACTTTGTTGCGAAAGTGGTAAT
TATCGCTTCCGGTGCTGCACCTAAACTTCTTGGCTGTCCGGGAGAGCAAGAATTCAGATCCCGGGGGGTTTCCTACTGTG
CTACCTGTGACGCCGCTTTTTACGAAGGCGCCAACGTCATGGTCGTAGGGGGTGGCGATTCAGCGGTTGAGGAAGCCTGT
TACCTTACCAAGTTTGCTGATAAGGTAACCCTTGTCCATCGCCGCGATACCTTGAGAGCCACCAAAGTTCTCCAGGAAAG
GGCTTTTGCCAACGAAAAGCTGGAAATCCTTTGGAACACCGTGGTGGAAGAAATTATCGGCACCGACGTTGTGGAAAAAG
TGCGCTTAAAAAACGTGGTCACCGGTGAAGTTTTTGAAAGGGAAATTGACGGAATCTTTATCTATGTTGGCCTTAAGCCC
AATACCGAGTTTGTCAAAGGCTTAGTAAACCTGGACGAACAGGGGTACATTATTACCGATGAAAACATGCGCACCAACAT
TCCCGGAATCTACGCCGCCGGCGATGTCCGGCAAAAACTGTTACGGCAGGTAGTAACTGCCGCTGCTGACGGTGCTATTG
CTGCTTACCATGCGGAAAAATATCTTGAAGAATGTACCGAGTAA

Upstream 100 bases:

>100_bases
GACCTGGATTTTTTTAAAAGTTTCCTTTACAGCATGGGTCTTATTACATAAGTTTATAACTTTAATTTATAACTTTTCCC
TTTAAAAGGAGGAATATCGT

Downstream 100 bases:

>100_bases
AGGAGGTGATAAACATGGCGGGAAACATAATTGAGCTAAACAAAGACAATTTTGAAGAAGAAGTTTTAAAAAGCGAGCTT
CCGGTTCTGGTGGACTTCTG

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MERYDVIIIGAGPAGLSAALYSARSKLSTLYIEKLSTGGQAATTDEIENYPGFAHGISGPELTAQMEEQAKRFGAKKLLA
EVKGIELAGADRIVKTTKGNFVAKVVIIASGAAPKLLGCPGEQEFRSRGVSYCATCDAAFYEGANVMVVGGGDSAVEEAC
YLTKFADKVTLVHRRDTLRATKVLQERAFANEKLEILWNTVVEEIIGTDVVEKVRLKNVVTGEVFEREIDGIFIYVGLKP
NTEFVKGLVNLDEQGYIITDENMRTNIPGIYAAGDVRQKLLRQVVTAAADGAIAAYHAEKYLEECTE

Sequences:

>Translated_307_residues
MERYDVIIIGAGPAGLSAALYSARSKLSTLYIEKLSTGGQAATTDEIENYPGFAHGISGPELTAQMEEQAKRFGAKKLLA
EVKGIELAGADRIVKTTKGNFVAKVVIIASGAAPKLLGCPGEQEFRSRGVSYCATCDAAFYEGANVMVVGGGDSAVEEAC
YLTKFADKVTLVHRRDTLRATKVLQERAFANEKLEILWNTVVEEIIGTDVVEKVRLKNVVTGEVFEREIDGIFIYVGLKP
NTEFVKGLVNLDEQGYIITDENMRTNIPGIYAAGDVRQKLLRQVVTAAADGAIAAYHAEKYLEECTE
>Mature_307_residues
MERYDVIIIGAGPAGLSAALYSARSKLSTLYIEKLSTGGQAATTDEIENYPGFAHGISGPELTAQMEEQAKRFGAKKLLA
EVKGIELAGADRIVKTTKGNFVAKVVIIASGAAPKLLGCPGEQEFRSRGVSYCATCDAAFYEGANVMVVGGGDSAVEEAC
YLTKFADKVTLVHRRDTLRATKVLQERAFANEKLEILWNTVVEEIIGTDVVEKVRLKNVVTGEVFEREIDGIFIYVGLKP
NTEFVKGLVNLDEQGYIITDENMRTNIPGIYAAGDVRQKLLRQVVTAAADGAIAAYHAEKYLEECTE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=293, Percent_Identity=29.0102389078498, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI21389617, Length=293, Percent_Identity=29.0102389078498, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI65787454, Length=293, Percent_Identity=29.0102389078498, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787114, Length=308, Percent_Identity=38.961038961039, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=34.1935483870968, Blast_Score=150, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=40, Blast_Score=222, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=38.7301587301587, Blast_Score=209, Evalue=5e-55,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33253; Mature: 33253

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERYDVIIIGAGPAGLSAALYSARSKLSTLYIEKLSTGGQAATTDEIENYPGFAHGISGP
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCC
ELTAQMEEQAKRFGAKKLLAEVKGIELAGADRIVKTTKGNFVAKVVIIASGAAPKLLGCP
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEECCCCCCEECCC
GEQEFRSRGVSYCATCDAAFYEGANVMVVGGGDSAVEEACYLTKFADKVTLVHRRDTLRA
CHHHHHHCCCCEEEECCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEHHHHHHHH
TKVLQERAFANEKLEILWNTVVEEIIGTDVVEKVRLKNVVTGEVFEREIDGIFIYVGLKP
HHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
NTEFVKGLVNLDEQGYIITDENMRTNIPGIYAAGDVRQKLLRQVVTAAADGAIAAYHAEK
CHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHH
YLEECTE
HHHHHCC
>Mature Secondary Structure
MERYDVIIIGAGPAGLSAALYSARSKLSTLYIEKLSTGGQAATTDEIENYPGFAHGISGP
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCC
ELTAQMEEQAKRFGAKKLLAEVKGIELAGADRIVKTTKGNFVAKVVIIASGAAPKLLGCP
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCEEEEEEEEECCCCCCEECCC
GEQEFRSRGVSYCATCDAAFYEGANVMVVGGGDSAVEEACYLTKFADKVTLVHRRDTLRA
CHHHHHHCCCCEEEECCHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEHHHHHHHH
TKVLQERAFANEKLEILWNTVVEEIIGTDVVEKVRLKNVVTGEVFEREIDGIFIYVGLKP
HHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
NTEFVKGLVNLDEQGYIITDENMRTNIPGIYAAGDVRQKLLRQVVTAAADGAIAAYHAEK
CHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHH
YLEECTE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8223622; 2537814 [H]