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The map label for this gene is zraS [C]

Identifier: 77748575

GI number: 77748575

Start: 1470143

End: 1471306

Strand: Direct

Name: zraS [C]

Synonym: XAC1282

Alternate gene names: 77748575

Gene position: 1470143-1471306 (Clockwise)

Preceding gene: 77748574

Following gene: 21242037

Centisome position: 28.41

GC content: 62.89

Gene sequence:

>1164_bases
ATGGATGCGGAAACGGCCGTCGACAGCGCAGGGCCGCTTTCTTACGACAGCCGGCAGTGTCAACTGTTGGTGCAGAGCGT
GTCCGATCATGCGATCTACATGCTCGATATCGGTGGGCATATTCGCAGCTGGAACCCCGGCGGCGAGCGCATCAAGGGCT
ACAGCGCAAGCGAGATATTAGGCACGCATTTCTCGCGGTTCTACCTGCCCGAGGATGCGCAACGCGACGAACCCAGCCGC
AATCTGGAAATCGCCAAGCGGGAAGGGCGCTTCGCTGCCGAAGGTTGGCGCTTGCGCAAGGACGGCAGCCGGTTCTGGGC
CAGCGTGGTGATCGAACCGGTGCTGGAATTCGGCGTGCTGGTGGGGTTTGCAAAAGTCACTCGCGATCTGACCGAGCGCC
GTGAGGCGCAGCATTTGCTGCAACAGGCGCAGCAGGCGTTGCTGCAATCGCAGAAGGTCGAAGCCTTGGGTCGGTTGACG
CTGGGCATGGCCCACGATTTCAACAACCTGCTCACGGTGATGGTGACCAGTCTGGATCTGATTGCGCTGCGCGCAGGCGA
GGACGCGCGCACCCGCATGTTGATCGAAGTGGCGCAAACTGCGGTGGATCGCGGCACCTTGCTGACGCGGCAACTGCTCG
CGTTCGCGCGCGGTCAACAACTGAACCCTGAGCGCCACCCGGTCAATGACATCGTGACGCGTTCGTTGGAACTGTTGCGG
CGTGCCTGTCCGCCGGGTGTGAGCTTGTCGTTGCAGTTTGCCGACGCACTGCCGCATGTGCGCGTAGACCCCGGTCAGCT
GGAGGCGGCGTTGCTCAATCTGGTCTTCAATAGTTGCGATGCGATGCCCTCTGGCGGCAGCATCGCGTTGCTCACTTCTG
CTGCGCAGCGATCCGAACCGTCAAGCCCACAAGGCGTCCGTCGCCCATACGTCGCCCTTGCCGTACGCGACGACGGTCCG
GGCATGTCCGCGCACGTTGCACAACGCGCCAGCGAGCCATTTTTCACCACCAAGGATGTCGGCAAGGGCTCCGGCCTGGG
CTTGAGCCAGGTCTATGGCTTCGCATCCCAGTCCGGTGGCTTCGTCGAGCTTGAGACCGCACCTGGACGCGGCACTACCG
TCACCGTGTTTCTCCCGGCCGTCGAGGAGGCCGAGCATGACTGA

Upstream 100 bases:

>100_bases
CGCCGGAAATTTGACGCTTTTTGCTGCCGCGTTGGCTTGCACGCAGCCTTCACGCAGCTATCAATATGGTCCCGCGCTTT
TCTGGGGGAATCATCGCGCG

Downstream 100 bases:

>100_bases
ATCCCTTCGCCTGCTGATGGTGGAAGACCAAGAAGAACTGCGCGAATTGATCGGCGAAGCGCTGCGCGATGCCGGCATCA
GCGTCGACACCGCCGATGAT

Product: two-component system sensor protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDAETAVDSAGPLSYDSRQCQLLVQSVSDHAIYMLDIGGHIRSWNPGGERIKGYSASEILGTHFSRFYLPEDAQRDEPSR
NLEIAKREGRFAAEGWRLRKDGSRFWASVVIEPVLEFGVLVGFAKVTRDLTERREAQHLLQQAQQALLQSQKVEALGRLT
LGMAHDFNNLLTVMVTSLDLIALRAGEDARTRMLIEVAQTAVDRGTLLTRQLLAFARGQQLNPERHPVNDIVTRSLELLR
RACPPGVSLSLQFADALPHVRVDPGQLEAALLNLVFNSCDAMPSGGSIALLTSAAQRSEPSSPQGVRRPYVALAVRDDGP
GMSAHVAQRASEPFFTTKDVGKGSGLGLSQVYGFASQSGGFVELETAPGRGTTVTVFLPAVEEAEHD

Sequences:

>Translated_387_residues
MDAETAVDSAGPLSYDSRQCQLLVQSVSDHAIYMLDIGGHIRSWNPGGERIKGYSASEILGTHFSRFYLPEDAQRDEPSR
NLEIAKREGRFAAEGWRLRKDGSRFWASVVIEPVLEFGVLVGFAKVTRDLTERREAQHLLQQAQQALLQSQKVEALGRLT
LGMAHDFNNLLTVMVTSLDLIALRAGEDARTRMLIEVAQTAVDRGTLLTRQLLAFARGQQLNPERHPVNDIVTRSLELLR
RACPPGVSLSLQFADALPHVRVDPGQLEAALLNLVFNSCDAMPSGGSIALLTSAAQRSEPSSPQGVRRPYVALAVRDDGP
GMSAHVAQRASEPFFTTKDVGKGSGLGLSQVYGFASQSGGFVELETAPGRGTTVTVFLPAVEEAEHD
>Mature_387_residues
MDAETAVDSAGPLSYDSRQCQLLVQSVSDHAIYMLDIGGHIRSWNPGGERIKGYSASEILGTHFSRFYLPEDAQRDEPSR
NLEIAKREGRFAAEGWRLRKDGSRFWASVVIEPVLEFGVLVGFAKVTRDLTERREAQHLLQQAQQALLQSQKVEALGRLT
LGMAHDFNNLLTVMVTSLDLIALRAGEDARTRMLIEVAQTAVDRGTLLTRQLLAFARGQQLNPERHPVNDIVTRSLELLR
RACPPGVSLSLQFADALPHVRVDPGQLEAALLNLVFNSCDAMPSGGSIALLTSAAQRSEPSSPQGVRRPYVALAVRDDGP
GMSAHVAQRASEPFFTTKDVGKGSGLGLSQVYGFASQSGGFVELETAPGRGTTVTVFLPAVEEAEHD

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.5833333333333, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788549, Length=370, Percent_Identity=26.4864864864865, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790300, Length=361, Percent_Identity=27.1468144044321, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42097; Mature: 42097

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAETAVDSAGPLSYDSRQCQLLVQSVSDHAIYMLDIGGHIRSWNPGGERIKGYSASEIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHCCCCCHHHHH
GTHFSRFYLPEDAQRDEPSRNLEIAKREGRFAAEGWRLRKDGSRFWASVVIEPVLEFGVL
HHHHHHEECCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VGFAKVTRDLTERREAQHLLQQAQQALLQSQKVEALGRLTLGMAHDFNNLLTVMVTSLDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALRAGEDARTRMLIEVAQTAVDRGTLLTRQLLAFARGQQLNPERHPVNDIVTRSLELLR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RACPPGVSLSLQFADALPHVRVDPGQLEAALLNLVFNSCDAMPSGGSIALLTSAAQRSEP
HHCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCC
SSPQGVRRPYVALAVRDDGPGMSAHVAQRASEPFFTTKDVGKGSGLGLSQVYGFASQSGG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEECCCCCCCCCCCHHHHHCCCCCCCC
FVELETAPGRGTTVTVFLPAVEEAEHD
EEEEECCCCCCCEEEEEECCHHCCCCC
>Mature Secondary Structure
MDAETAVDSAGPLSYDSRQCQLLVQSVSDHAIYMLDIGGHIRSWNPGGERIKGYSASEIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHCCCCCHHHHH
GTHFSRFYLPEDAQRDEPSRNLEIAKREGRFAAEGWRLRKDGSRFWASVVIEPVLEFGVL
HHHHHHEECCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHH
VGFAKVTRDLTERREAQHLLQQAQQALLQSQKVEALGRLTLGMAHDFNNLLTVMVTSLDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALRAGEDARTRMLIEVAQTAVDRGTLLTRQLLAFARGQQLNPERHPVNDIVTRSLELLR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
RACPPGVSLSLQFADALPHVRVDPGQLEAALLNLVFNSCDAMPSGGSIALLTSAAQRSEP
HHCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCC
SSPQGVRRPYVALAVRDDGPGMSAHVAQRASEPFFTTKDVGKGSGLGLSQVYGFASQSGG
CCCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCEECCCCCCCCCCCHHHHHCCCCCCCC
FVELETAPGRGTTVTVFLPAVEEAEHD
EEEEECCCCCCCEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA