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The map label for this gene is glmS [H]

Identifier: 77748548

GI number: 77748548

Start: 848191

End: 849219

Strand: Direct

Name: glmS [H]

Synonym: XAC0714

Alternate gene names: 77748548

Gene position: 848191-849219 (Clockwise)

Preceding gene: 21241484

Following gene: 21241486

Centisome position: 16.39

GC content: 67.25

Gene sequence:

>1029_bases
ATGAGCCTTCCCTCCGAAACCGAGACCTTGATGTTCCGCGAAGCGGCGCAGACCGCCGATGTGGTCGCTGCACAGTTCGC
ACGTAATGCCGACACCATCGCCGCGCTTGTGCAATCGCTGCGCGAGACGCCGCCGCCGTTCGTGGTGACCTGCGCGCGCG
GTAGCTCCGATCATGCGGCCACCTATGCCAAGTACCTGTTCGAAACCCAGCTCGGCATCGTCACCGCATCTGCGTCGCCG
TCGGTGGGCTCGGTCTATGCAGCGCCGCTGCAACTGCGTGGCGCGCTGTACATCGTGATTTCGCAATCGGGCAAGAGCCC
GGATCTGCTGCGTAATGCCGAAGCCGCCAAGGCTGCCGGCGCGCGCGTGGTCGCCCTGGTCAACGTGGAAGATTCGCCGC
TGGCGCAACTGGCCGAGGTGGTGATTCCGCTGGGCGCAGGCCCGGAAAGAAGCGTGGCCGCCACCAAGAGTTATCTCGCT
TCGCTGGCCGCGGTCCTGCATCTGGGCGCGGTGTGGAAGAACGACCCCGCCTTGCTTGCCGCGCTCGACGCATTGCCGCA
GCAGTTGCGCAGCGCGTGGCAGGCCGATTGGTCCGCGCTCACCGCCGGTCTGGCGCCTGCGCACAATCTGTTCGTGCTCG
GCCGCGGCCTGGGCCTGGGCGCAGCGCAGGAAGCGGCACTGAAGTTCAAGGAAACCTGCGGCCTGCACGCCGAAGCCTAC
AGCTCGGCCGAGGTCAAGCACGGGCCGATGGCCCTGGTGGGGCCGGGGTTCCCGGTGCTGGTCTTCGCACAGCCCGACGA
AACCGGTGCCGGTACCCGCGCACTGGCCGAAGAATTCCGCGCGCGTGGCGCGCAGGTGTGGCTGGCCGCGCCCGGTGGCG
ATTTGCCGCTGGCAGAGGCCGCGCACCCGGCCTGTGCGCCGCTGTTGACCGTGCAGAGCTTCTATCGCGCGATCAATGCA
TTGGCATTGCAGCGCGGCAACAATCCCGATCTGCCGCCGCATCTGAACAAGGTCACGGAAACCGTCTGA

Upstream 100 bases:

>100_bases
GAGCCGCGGCTTCGTGCCGCAGTTGGTGGTGCGCGGCTCCACCGCGCCGGCGCCTGCGTCCACCGGCAAACCCCTTCCTC
CTGAATCTGCCTGAGCCACG

Downstream 100 bases:

>100_bases
TCATGCACGCTCTCACGACTCAGGCACTGTGCAATGCACGTGTGCTCACCGACAACGGATTGCAGGACGGCCTGGTCGTG
ATGCTGGCTGGCACGCAGAT

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSLPSETETLMFREAAQTADVVAAQFARNADTIAALVQSLRETPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASP
SVGSVYAAPLQLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLAEVVIPLGAGPERSVAATKSYLA
SLAAVLHLGAVWKNDPALLAALDALPQQLRSAWQADWSALTAGLAPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
SSAEVKHGPMALVGPGFPVLVFAQPDETGAGTRALAEEFRARGAQVWLAAPGGDLPLAEAAHPACAPLLTVQSFYRAINA
LALQRGNNPDLPPHLNKVTETV

Sequences:

>Translated_342_residues
MSLPSETETLMFREAAQTADVVAAQFARNADTIAALVQSLRETPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASP
SVGSVYAAPLQLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLAEVVIPLGAGPERSVAATKSYLA
SLAAVLHLGAVWKNDPALLAALDALPQQLRSAWQADWSALTAGLAPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
SSAEVKHGPMALVGPGFPVLVFAQPDETGAGTRALAEEFRARGAQVWLAAPGGDLPLAEAAHPACAPLLTVQSFYRAINA
LALQRGNNPDLPPHLNKVTETV
>Mature_341_residues
SLPSETETLMFREAAQTADVVAAQFARNADTIAALVQSLRETPPPFVVTCARGSSDHAATYAKYLFETQLGIVTASASPS
VGSVYAAPLQLRGALYIVISQSGKSPDLLRNAEAAKAAGARVVALVNVEDSPLAQLAEVVIPLGAGPERSVAATKSYLAS
LAAVLHLGAVWKNDPALLAALDALPQQLRSAWQADWSALTAGLAPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAYS
SAEVKHGPMALVGPGFPVLVFAQPDETGAGTRALAEEFRARGAQVWLAAPGGDLPLAEAAHPACAPLLTVQSFYRAINAL
ALQRGNNPDLPPHLNKVTETV

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=322, Percent_Identity=25.4658385093168, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI205277386, Length=322, Percent_Identity=23.6024844720497, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1790167, Length=329, Percent_Identity=28.8753799392097, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17532899, Length=323, Percent_Identity=27.8637770897833, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17532897, Length=323, Percent_Identity=27.8637770897833, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17539970, Length=315, Percent_Identity=27.3015873015873, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322745, Length=314, Percent_Identity=25.1592356687898, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323731, Length=231, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357745, Length=334, Percent_Identity=25.4491017964072, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35491; Mature: 35360

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPSETETLMFREAAQTADVVAAQFARNADTIAALVQSLRETPPPFVVTCARGSSDHAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
TYAKYLFETQLGIVTASASPSVGSVYAAPLQLRGALYIVISQSGKSPDLLRNAEAAKAAG
HHHHHHHHHHHCEEEECCCCCCCCEEECCEEECCEEEEEEECCCCCCHHHHCCHHHHHCC
ARVVALVNVEDSPLAQLAEVVIPLGAGPERSVAATKSYLASLAAVLHLGAVWKNDPALLA
CEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALDALPQQLRSAWQADWSALTAGLAPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHC
SSAEVKHGPMALVGPGFPVLVFAQPDETGAGTRALAEEFRARGAQVWLAAPGGDLPLAEA
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHC
AHPACAPLLTVQSFYRAINALALQRGNNPDLPPHLNKVTETV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SLPSETETLMFREAAQTADVVAAQFARNADTIAALVQSLRETPPPFVVTCARGSSDHAA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
TYAKYLFETQLGIVTASASPSVGSVYAAPLQLRGALYIVISQSGKSPDLLRNAEAAKAAG
HHHHHHHHHHHCEEEECCCCCCCCEEECCEEECCEEEEEEECCCCCCHHHHCCHHHHHCC
ARVVALVNVEDSPLAQLAEVVIPLGAGPERSVAATKSYLASLAAVLHLGAVWKNDPALLA
CEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALDALPQQLRSAWQADWSALTAGLAPAHNLFVLGRGLGLGAAQEAALKFKETCGLHAEAY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHC
SSAEVKHGPMALVGPGFPVLVFAQPDETGAGTRALAEEFRARGAQVWLAAPGGDLPLAEA
CCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHC
AHPACAPLLTVQSFYRAINALALQRGNNPDLPPHLNKVTETV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]