Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 21241486

GI number: 21241486

Start: 849222

End: 850376

Strand: Direct

Name: nagA [H]

Synonym: XAC0715

Alternate gene names: 21241486

Gene position: 849222-850376 (Clockwise)

Preceding gene: 77748548

Following gene: 21241487

Centisome position: 16.41

GC content: 66.67

Gene sequence:

>1155_bases
ATGCACGCTCTCACGACTCAGGCACTGTGCAATGCACGTGTGCTCACCGACAACGGATTGCAGGACGGCCTGGTCGTGAT
GCTGGCTGGCACGCAGATCCAGGCGATCGTGCCGGCCGACGATGCGCGCGTTACGCAGGCCGATACGCGCCTGGACCTGG
GTGGCGCCAGCTTGTTGCCGGGCTTTATCGACATCCAGGTCAATGGCGGCGGCGGCGTGTTGTTCAACAACGCACGCGAC
CCCCAGGCACTGGCCACGATCGCCGCCGCGCATCGTCGCTTCGGCACCACCGGCATGCTGCCAACCTTGATCAGCGACAC
CGCTGAGGTGATGGCCGAAGCGATCGATGCCACTCGCCAGGCCATCGCGCAAGGCGTACCCGGCGTGCTCGGCATCCATC
TGGAGGGCCCGTACCTGAGTCCTGCGCGCAAGGGCACGCACGACGCGGACAAGTTCCGCGTACCGGACGCGCACGAGATT
GCCGTCGATACCTCATTGGACAATGGCGTCACCTTGATCACGCTCGCACCCGAGCGCGTTCCGCTGGACGATATCCGTGC
CTTCGTTGCCGGCGGCGCGCTCGTGTTCGCCGGCCACACTGCGGCCACCTACGAGCAGGCACGCGATGGCATTGCCGCCG
GCGTCAGCGGCTTCACGCACGTGTACAACGCGATGTCGCAGCTGGCTGGCCGCGAACCCAATGCGGTGGGCGCGGCACTG
GAAGACCCGACGATTTGGTGCGGCGTCATCGTCGACGGCGTGCACGTGCATCCGGCCAGCTTGCGTGTGGCGCTCGCGGC
CAAGCCACGCGGCAAGTTGCTGCTGGTCACCGACGCCATGCCGATGGTCGGCAGCGAAAGCGCCAGCTTCGATCTCTACG
GCGAAACCATCACCGCCGTGGACGGCGTGGTGCGAAATGCCGATGGTGCACTGGCCGGCTCCGCATTGGACATGGCCACC
GCCGTGCGCAACAGCGTGCGCTGGCTGGGCGTGGACCTGGCCGAAGCCGCGCGCATGGCTTCTACCTACCCCGCGCAATG
CATTGGCCTGGGCGAACGCCTGGGACGCATCGCCCCCGGCTACCAAGCCGATCTGGTGCTGGTGGATGACGATGTGCAGG
TGTTGAGCACGTGGGTGGCTGGGCAGCGCGACTAA

Upstream 100 bases:

>100_bases
TGCAGAGCTTCTATCGCGCGATCAATGCATTGGCATTGCAGCGCGGCAACAATCCCGATCTGCCGCCGCATCTGAACAAG
GTCACGGAAACCGTCTGATC

Downstream 100 bases:

>100_bases
GCGCCGCCGCCCACACGCCTGCGTCGCCGCAGCGGAACGCGGCCGGTGCTCGGAGCGGCACGACCACCGGTCCGCTGCCG
CTGCCGTGCGCTGACCGTGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MHALTTQALCNARVLTDNGLQDGLVVMLAGTQIQAIVPADDARVTQADTRLDLGGASLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAEVMAEAIDATRQAIAQGVPGVLGIHLEGPYLSPARKGTHDADKFRVPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGALVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPTIWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSESASFDLYGETITAVDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDDDVQVLSTWVAGQRD

Sequences:

>Translated_384_residues
MHALTTQALCNARVLTDNGLQDGLVVMLAGTQIQAIVPADDARVTQADTRLDLGGASLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAEVMAEAIDATRQAIAQGVPGVLGIHLEGPYLSPARKGTHDADKFRVPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGALVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPTIWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSESASFDLYGETITAVDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDDDVQVLSTWVAGQRD
>Mature_384_residues
MHALTTQALCNARVLTDNGLQDGLVVMLAGTQIQAIVPADDARVTQADTRLDLGGASLLPGFIDIQVNGGGGVLFNNARD
PQALATIAAAHRRFGTTGMLPTLISDTAEVMAEAIDATRQAIAQGVPGVLGIHLEGPYLSPARKGTHDADKFRVPDAHEI
AVDTSLDNGVTLITLAPERVPLDDIRAFVAGGALVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
EDPTIWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSESASFDLYGETITAVDGVVRNADGALAGSALDMAT
AVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPGYQADLVLVDDDVQVLSTWVAGQRD

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=383, Percent_Identity=33.9425587467363, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI224922791, Length=382, Percent_Identity=34.0314136125654, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1786892, Length=381, Percent_Identity=39.1076115485564, Blast_Score=251, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17553768, Length=359, Percent_Identity=32.3119777158774, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19920392, Length=348, Percent_Identity=33.6206896551724, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI281361140, Length=363, Percent_Identity=33.8842975206612, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39822; Mature: 39822

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHALTTQALCNARVLTDNGLQDGLVVMLAGTQIQAIVPADDARVTQADTRLDLGGASLLP
CCCCCHHHHHCCEEEECCCCCCCEEEEEECCEEEEEECCCCCEEEECCCEEECCCHHHCC
GFIDIQVNGGGGVLFNNARDPQALATIAAAHRRFGTTGMLPTLISDTAEVMAEAIDATRQ
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIAQGVPGVLGIHLEGPYLSPARKGTHDADKFRVPDAHEIAVDTSLDNGVTLITLAPERV
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCEEEEEECCCCC
PLDDIRAFVAGGALVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
CHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDPTIWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSESASFDLYGETITAV
CCCCEEEEEEECCEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCEEECCCHHHHH
DGVVRNADGALAGSALDMATAVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPG
HHHHCCCCCCCCCHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
YQADLVLVDDDVQVLSTWVAGQRD
CCEEEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure
MHALTTQALCNARVLTDNGLQDGLVVMLAGTQIQAIVPADDARVTQADTRLDLGGASLLP
CCCCCHHHHHCCEEEECCCCCCCEEEEEECCEEEEEECCCCCEEEECCCEEECCCHHHCC
GFIDIQVNGGGGVLFNNARDPQALATIAAAHRRFGTTGMLPTLISDTAEVMAEAIDATRQ
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIAQGVPGVLGIHLEGPYLSPARKGTHDADKFRVPDAHEIAVDTSLDNGVTLITLAPERV
HHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCEEEEEECCCCC
PLDDIRAFVAGGALVFAGHTAATYEQARDGIAAGVSGFTHVYNAMSQLAGREPNAVGAAL
CHHHHHHHHHCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDPTIWCGVIVDGVHVHPASLRVALAAKPRGKLLLVTDAMPMVGSESASFDLYGETITAV
CCCCEEEEEEECCEEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCEEECCCHHHHH
DGVVRNADGALAGSALDMATAVRNSVRWLGVDLAEAARMASTYPAQCIGLGERLGRIAPG
HHHHCCCCCCCCCHHHHHHHHHHHCHHEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCCC
YQADLVLVDDDVQVLSTWVAGQRD
CCEEEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]