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The map label for this gene is ltaE [H]

Identifier: 77748529

GI number: 77748529

Start: 567785

End: 568846

Strand: Direct

Name: ltaE [H]

Synonym: XAC0477

Alternate gene names: 77748529

Gene position: 567785-568846 (Clockwise)

Preceding gene: 21241249

Following gene: 21241251

Centisome position: 10.97

GC content: 64.69

Gene sequence:

>1062_bases
ATGGACGGGCAGGGTAGCGCTACGCGCATCAGCTTTCGCAACGACTACAGCGAAGGCGCGCATCCGCGGCTGTTGCAGGC
GTTGGCGCAGGCCAGCGCCGAGCAGCATGCCGGCTATGGCACCGATCGGCACACAGCGCGTGCGGTTGCGTTGATCCGCA
CCGCAGTCGCGCAGCCGCAGGCCGACGTGCATCTGCTGGTCGGCGGCACGCAGACCAATCTGATTGCGATCAGCGCGTTC
TTGCGCCCGCATCAGGCAGTCATCGCGGTGGACGCGGCGCATATCGCCACGCACGAGACCGGCGCCATCGAAGCGACCGG
CCACAAGGTGCTCACCGTGCCGGCGCTGCACGACAAGCTGACGCCTGCGCTGATTCAGCCGGTGCTGGCTGTGCACAGCA
ACGAACACATGGTGCAGCCGCGTCTGGTCTACATTTCCAACAGCACCGAAAGCGGCACCATCTATACGCGCGCCGAACTC
GATGCGTTGTCGCGGTTTTGTCGCGCGAACGATTTGCTGCTGTACCTGGATGGCGCGCGTCTGGGTGCGGCGCTGACCGC
CGACGGCAACGATCTGGATCTGCCGGCCATTGCCACGCTGACCGACGCGTTCTATATCGGTGGCACCAAGAATGGTGCGC
TGCTCGGCGAAGCGCTGGTCATCGTCAATCCCGCCCTGCAGGCGGATTTGCGTTATCTGATCAAGCAGCGCGGCGCGCTA
CTGGCCAAGGGCATGGTGGTTGGTGCGCAATTTGCGGCGTTGTTCGAAGACAGTCTGTTCTTCGAACTGGCCGCGCATGC
CAATGCCATGGCGCAACGCTTGCGCGCCGGCCTGCTTGCGGCCGGCGCGCACTTCACCAGCGACTCGCCGACCAACCAGC
AGTTCATCGCCGTCAGCGCGCAACACGCTGCGCAGCTCGTGCAACGCTACGACTTCGAGCGCTGGGAAGTGCGCACCGAT
GGCAGTCAGGTAATCCGCTTCGTGACCTCGTGGGCGACCACAGCCGCGTCGGTCGATCGGCTGTGTGCGGATGTTGCCGC
ACTTCATCGCGGCGTGTCGTAA

Upstream 100 bases:

>100_bases
GCGTGGTCTACGACTCCGACCCCGACCTGGAGTGGCAGGAAACCATGAACAAGGGGCGTGCGCTGTTTCGCGCAGTTGCC
CAGGCGGCGAAGGGCCTGTG

Downstream 100 bases:

>100_bases
GCATGCGCACCAGAGCGAGCGAAACAGATGAAGCAACTCGAACGCCGGAATTTTGCCCATCCCGGTTCGCTCGATGCTGG
TCAGGTGTGGCAGTCACGCC

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MDGQGSATRISFRNDYSEGAHPRLLQALAQASAEQHAGYGTDRHTARAVALIRTAVAQPQADVHLLVGGTQTNLIAISAF
LRPHQAVIAVDAAHIATHETGAIEATGHKVLTVPALHDKLTPALIQPVLAVHSNEHMVQPRLVYISNSTESGTIYTRAEL
DALSRFCRANDLLLYLDGARLGAALTADGNDLDLPAIATLTDAFYIGGTKNGALLGEALVIVNPALQADLRYLIKQRGAL
LAKGMVVGAQFAALFEDSLFFELAAHANAMAQRLRAGLLAAGAHFTSDSPTNQQFIAVSAQHAAQLVQRYDFERWEVRTD
GSQVIRFVTSWATTAASVDRLCADVAALHRGVS

Sequences:

>Translated_353_residues
MDGQGSATRISFRNDYSEGAHPRLLQALAQASAEQHAGYGTDRHTARAVALIRTAVAQPQADVHLLVGGTQTNLIAISAF
LRPHQAVIAVDAAHIATHETGAIEATGHKVLTVPALHDKLTPALIQPVLAVHSNEHMVQPRLVYISNSTESGTIYTRAEL
DALSRFCRANDLLLYLDGARLGAALTADGNDLDLPAIATLTDAFYIGGTKNGALLGEALVIVNPALQADLRYLIKQRGAL
LAKGMVVGAQFAALFEDSLFFELAAHANAMAQRLRAGLLAAGAHFTSDSPTNQQFIAVSAQHAAQLVQRYDFERWEVRTD
GSQVIRFVTSWATTAASVDRLCADVAALHRGVS
>Mature_353_residues
MDGQGSATRISFRNDYSEGAHPRLLQALAQASAEQHAGYGTDRHTARAVALIRTAVAQPQADVHLLVGGTQTNLIAISAF
LRPHQAVIAVDAAHIATHETGAIEATGHKVLTVPALHDKLTPALIQPVLAVHSNEHMVQPRLVYISNSTESGTIYTRAEL
DALSRFCRANDLLLYLDGARLGAALTADGNDLDLPAIATLTDAFYIGGTKNGALLGEALVIVNPALQADLRYLIKQRGAL
LAKGMVVGAQFAALFEDSLFFELAAHANAMAQRLRAGLLAAGAHFTSDSPTNQQFIAVSAQHAAQLVQRYDFERWEVRTD
GSQVIRFVTSWATTAASVDRLCADVAALHRGVS

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37637; Mature: 37637

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGQGSATRISFRNDYSEGAHPRLLQALAQASAEQHAGYGTDRHTARAVALIRTAVAQPQ
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
ADVHLLVGGTQTNLIAISAFLRPHQAVIAVDAAHIATHETGAIEATGHKVLTVPALHDKL
CCEEEEECCCCCCCEEEEEHHCCCEEEEEEEHHHHEECCCCCEEECCCEEEEECCHHHHC
TPALIQPVLAVHSNEHMVQPRLVYISNSTESGTIYTRAELDALSRFCRANDLLLYLDGAR
CHHHHHHHHHHCCCCCEECCEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCC
LGAALTADGNDLDLPAIATLTDAFYIGGTKNGALLGEALVIVNPALQADLRYLIKQRGAL
CCEEEECCCCCCCCCHHHHHHHHEEECCCCCCCHHHCEEEEECHHHHHHHHHHHHHCCCH
LAKGMVVGAQFAALFEDSLFFELAAHANAMAQRLRAGLLAAGAHFTSDSPTNQQFIAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEH
QHAAQLVQRYDFERWEVRTDGSQVIRFVTSWATTAASVDRLCADVAALHRGVS
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDGQGSATRISFRNDYSEGAHPRLLQALAQASAEQHAGYGTDRHTARAVALIRTAVAQPQ
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
ADVHLLVGGTQTNLIAISAFLRPHQAVIAVDAAHIATHETGAIEATGHKVLTVPALHDKL
CCEEEEECCCCCCCEEEEEHHCCCEEEEEEEHHHHEECCCCCEEECCCEEEEECCHHHHC
TPALIQPVLAVHSNEHMVQPRLVYISNSTESGTIYTRAELDALSRFCRANDLLLYLDGAR
CHHHHHHHHHHCCCCCEECCEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCC
LGAALTADGNDLDLPAIATLTDAFYIGGTKNGALLGEALVIVNPALQADLRYLIKQRGAL
CCEEEECCCCCCCCCHHHHHHHHEEECCCCCCCHHHCEEEEECHHHHHHHHHHHHHCCCH
LAKGMVVGAQFAALFEDSLFFELAAHANAMAQRLRAGLLAAGAHFTSDSPTNQQFIAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEH
QHAAQLVQRYDFERWEVRTDGSQVIRFVTSWATTAASVDRLCADVAALHRGVS
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]