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The map label for this gene is trpG [H]

Identifier: 21241251

GI number: 21241251

Start: 569044

End: 569622

Strand: Direct

Name: trpG [H]

Synonym: XAC0478

Alternate gene names: 21241251

Gene position: 569044-569622 (Clockwise)

Preceding gene: 77748529

Following gene: 21241252

Centisome position: 10.99

GC content: 61.83

Gene sequence:

>579_bases
ATGCTGCTGATGCTCGACAACTACGACAGCTTCACCTACAACCTCGTGCAGTACCTGCAGGCGCTGGGCGCCGAGGTCAC
GGTGGTGCGCAACGACGCCATGAGCGTCGACCAGATCGCCGCGCTCAGGCCCGAGCGCATCGTCATCTCGCCCGGTCCGT
GTACGCCCAACGAGGCAGGCATCTCGCTGCAATTGATCGAGCAGCTGGGTCAGACCACACCGATCCTGGGCGTGTGCCTG
GGCCATCAAAGCATCGGCCAGGTCTACGGTGGCGATGTGATCCGCGCCGGCAACATCATGCACGGCAAGACCTCGCCGAT
TCGTCATCAGGGCAAGGGCGTGTTCGCCGGTCTGCCGGACAGCTACGAGGCCACGCGCTATCACTCGCTGGTGGTGGACA
AGACCACCTTGCCGGACGCACTGGAGGTTACCGCCTGGACCGAAAATCCGGATGGTTCGATGGAAGAGGTCATGGGCTTG
CGCCATCGCCAGTTTCCGGTCGAAGGCGTGCAGTTCCATCCCGAATCGATCCTGACCCAGCACGGACATGCCTTGCTGAA
AAACTTTTTGCAGCGTTGA

Upstream 100 bases:

>100_bases
GCCGCGCCATCACCGATCGCAGAGTCACCTGCAGCCGGCAGCCAGACCTTCACCCAAAACATCTATGCGGTCTTTCTGAT
CGCGCAATGAGTCCCCTGCC

Downstream 100 bases:

>100_bases
TAGTGATGCGTCGTCTGCGCCTCGGCGTGACGACCGTGTCGCGCTGCGTCGCTACAACGCCAACGCAGAAGTGCAGTGGC
ACTCAACGTGCGCACCGTAC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLMLDNYDSFTYNLVQYLQALGAEVTVVRNDAMSVDQIAALRPERIVISPGPCTPNEAGISLQLIEQLGQTTPILGVCL
GHQSIGQVYGGDVIRAGNIMHGKTSPIRHQGKGVFAGLPDSYEATRYHSLVVDKTTLPDALEVTAWTENPDGSMEEVMGL
RHRQFPVEGVQFHPESILTQHGHALLKNFLQR

Sequences:

>Translated_192_residues
MLLMLDNYDSFTYNLVQYLQALGAEVTVVRNDAMSVDQIAALRPERIVISPGPCTPNEAGISLQLIEQLGQTTPILGVCL
GHQSIGQVYGGDVIRAGNIMHGKTSPIRHQGKGVFAGLPDSYEATRYHSLVVDKTTLPDALEVTAWTENPDGSMEEVMGL
RHRQFPVEGVQFHPESILTQHGHALLKNFLQR
>Mature_192_residues
MLLMLDNYDSFTYNLVQYLQALGAEVTVVRNDAMSVDQIAALRPERIVISPGPCTPNEAGISLQLIEQLGQTTPILGVCL
GHQSIGQVYGGDVIRAGNIMHGKTSPIRHQGKGVFAGLPDSYEATRYHSLVVDKTTLPDALEVTAWTENPDGSMEEVMGL
RHRQFPVEGVQFHPESILTQHGHALLKNFLQR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=59.8958333333333, Blast_Score=249, Evalue=7e-68,
Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=42.7083333333333, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786215, Length=180, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=48.6910994764398, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=34.4339622641509, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21088; Mature: 21088

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMLDNYDSFTYNLVQYLQALGAEVTVVRNDAMSVDQIAALRPERIVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLQLIEQLGQTTPILGVCLGHQSIGQVYGGDVIRAGNIMHGKTSPIRHQGKGVFAGLPD
CCHHHHHHHCCCCCEEEEECCCHHHHHHHCCCEEEECCEECCCCCCCCCCCCEEEECCCC
SYEATRYHSLVVDKTTLPDALEVTAWTENPDGSMEEVMGLRHRQFPVEGVQFHPESILTQ
CCCHHHHEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHH
HGHALLKNFLQR
CCHHHHHHHHCC
>Mature Secondary Structure
MLLMLDNYDSFTYNLVQYLQALGAEVTVVRNDAMSVDQIAALRPERIVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLQLIEQLGQTTPILGVCLGHQSIGQVYGGDVIRAGNIMHGKTSPIRHQGKGVFAGLPD
CCHHHHHHHCCCCCEEEEECCCHHHHHHHCCCEEEECCEECCCCCCCCCCCCEEEECCCC
SYEATRYHSLVVDKTTLPDALEVTAWTENPDGSMEEVMGLRHRQFPVEGVQFHPESILTQ
CCCHHHHEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHH
HGHALLKNFLQR
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]