Click here to switch to the map view.

The map label for this gene is hpsA [H]

Identifier: 77465665

GI number: 77465665

Start: 766355

End: 767011

Strand: Reverse

Name: hpsA [H]

Synonym: RSP_3657

Alternate gene names: 77465665

Gene position: 767011-766355 (Counterclockwise)

Preceding gene: 77465666

Following gene: 77465664

Centisome position: 81.34

GC content: 74.12

Gene sequence:

>657_bases
ATGATCCGGCACCCCCGACGCCCCACGGCCGCGCTGGACCCTGACCTGATCGAGCGGTTGCGCGCCCTGCAGCCCGCCTC
GCTCGGGCACCATCTGACGGCGGGGTTCCTTTCGCCCCGGATCCGCGCGCTGGTGCCGGGGCGCATGCTCGGCCGCGCGA
TCACCGTGCGCCAGCCGCTGCCCGATGCGGAGCCAGTGCACCGCGTGCTCGATGCGATCCGGCCGGGGGACGTGCTGGTC
ATCGACCGGTGCGGCGACGACCGGATCGCCTGCGTGGGCGAGATGGTGGCGCTGGCCGCGCGGACCGCGGGCGCGGCGGG
GATCGTGGTGGACGGCATGGTGACCGACATCGCCGAGATCGCGGCCCTGGGCCTTCCGCTCTTCGCGCGCGGCACGAGTG
TCGTCACCACGCGTCCGCTGCGGGCGCCGGGGGCCGAGCTTTTCGGCACCGTCTGTCCCGGCGGCGTTCCGGTGCGGGAC
GGCGACCTGATCTTCGGAGACGAGAACGGCCTGCTCTGTCTCGACCCGGAACGCCCGGATCTTGCGGCGCTGGTCGCGTG
CGCCGAGGCGGACGAGGCGCGCGAGGTCGACTGGCGCCGGCGTCTCGCCGCCGGCGAAAGCCTGGCCGTGCTCAACGGCT
ACGACACCCAGACCTGA

Upstream 100 bases:

>100_bases
AGGGCGGCGACATGCTGCTGGTCGGCAATGACATCGGCTTCCTGAATCAGGGCTGCCGCACGGCGGCAGGGATCGCCACG
GCGCTGCGGGAGACCCGGGC

Downstream 100 bases:

>100_bases
CCGCCCGCGGTCGGACGACATCTCAGACACGGGAGCCTTTCATGCTCGACACATCCGTCTTCACGCCGCACGGCAAGCAC
CTGATCGCGGGCGAATGGGT

Product: putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIRHPRRPTAALDPDLIERLRALQPASLGHHLTAGFLSPRIRALVPGRMLGRAITVRQPLPDAEPVHRVLDAIRPGDVLV
IDRCGDDRIACVGEMVALAARTAGAAGIVVDGMVTDIAEIAALGLPLFARGTSVVTTRPLRAPGAELFGTVCPGGVPVRD
GDLIFGDENGLLCLDPERPDLAALVACAEADEAREVDWRRRLAAGESLAVLNGYDTQT

Sequences:

>Translated_218_residues
MIRHPRRPTAALDPDLIERLRALQPASLGHHLTAGFLSPRIRALVPGRMLGRAITVRQPLPDAEPVHRVLDAIRPGDVLV
IDRCGDDRIACVGEMVALAARTAGAAGIVVDGMVTDIAEIAALGLPLFARGTSVVTTRPLRAPGAELFGTVCPGGVPVRD
GDLIFGDENGLLCLDPERPDLAALVACAEADEAREVDWRRRLAAGESLAVLNGYDTQT
>Mature_218_residues
MIRHPRRPTAALDPDLIERLRALQPASLGHHLTAGFLSPRIRALVPGRMLGRAITVRQPLPDAEPVHRVLDAIRPGDVLV
IDRCGDDRIACVGEMVALAARTAGAAGIVVDGMVTDIAEIAALGLPLFARGTSVVTTRPLRAPGAELFGTVCPGGVPVRD
GDLIFGDENGLLCLDPERPDLAALVACAEADEAREVDWRRRLAAGESLAVLNGYDTQT

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 23095; Mature: 23095

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRHPRRPTAALDPDLIERLRALQPASLGHHLTAGFLSPRIRALVPGRMLGRAITVRQPL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHCCHHHHCCEEEECCCC
PDAEPVHRVLDAIRPGDVLVIDRCGDDRIACVGEMVALAARTAGAAGIVVDGMVTDIAEI
CCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
AALGLPLFARGTSVVTTRPLRAPGAELFGTVCPGGVPVRDGDLIFGDENGLLCLDPERPD
HHHCCCHHHCCCEEEEECCCCCCCHHHHHHCCCCCEEECCCCEEEECCCCEEEECCCCCC
LAALVACAEADEAREVDWRRRLAAGESLAVLNGYDTQT
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MIRHPRRPTAALDPDLIERLRALQPASLGHHLTAGFLSPRIRALVPGRMLGRAITVRQPL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHCCHHHHCCEEEECCCC
PDAEPVHRVLDAIRPGDVLVIDRCGDDRIACVGEMVALAARTAGAAGIVVDGMVTDIAEI
CCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
AALGLPLFARGTSVVTTRPLRAPGAELFGTVCPGGVPVRDGDLIFGDENGLLCLDPERPD
HHHCCCHHHCCCEEEEECCCCCCCHHHHHHCCCCCEEECCCCEEEECCCCEEEECCCCCC
LAALVACAEADEAREVDWRRRLAAGESLAVLNGYDTQT
HHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA