Click here to switch to the map view.

The map label for this gene is aldH [H]

Identifier: 77465664

GI number: 77465664

Start: 764787

End: 766313

Strand: Reverse

Name: aldH [H]

Synonym: RSP_3656

Alternate gene names: 77465664

Gene position: 766313-764787 (Counterclockwise)

Preceding gene: 77465665

Following gene: 77465663

Centisome position: 81.26

GC content: 72.17

Gene sequence:

>1527_bases
ATGCTCGACACATCCGTCTTCACGCCGCACGGCAAGCACCTGATCGCGGGCGAATGGGTGGCTGGCGAGACCAGCTTCAC
CTCCGATCCCGCCCACGGCCCGAGCCACGCCTTCTCGGTCGGCACGCCTGACCTCGTCGACTGCGCCTGCCGGGCCGCCG
AGGAGGCCTTCTGGACCTACGGCCAGACGACCCGCGAAAGCCGCGCCGTCTTCCTGCGGGCCATCGCCGACGAGATCGAG
GCCCGCGCCGAGGCGATCACCGAGATCGGCAGTCGGGAGACCGGCCTGCCCGAGGCGCGGCTTCAGGGCGAGCGTGGCCG
CACCACCGGGCAGTTGCGGCTCTTCGCCGAGCACATCCTCGAGGGGGGACATCTCGACCGCCGTCACGACGTGGCGCTGC
CCGAACGCCAGCCGCTGCCGCGCCCCGACATCCGGCTCGTGATGCGTCCCATAGGCCCGGTCGCGGTCTTCGGCGCCTCG
AACTTCCCGCTCGCCTTCTCCACCGCCGGCGGCGACACGGCCGCTGCGCTGGCCGCGGGCTGTCCCGTGGTGGTCAAGGG
CCATGGCGCGCACCCCGGCACCGCCGAGATCGTCGCCGAGGCGATCCTCGCCGCGATCAGGAAGACGGGGATGCCGGACG
GCGTCTTCTCTCTGATTCAGGGCGGCCGGCGCGACGTGGGTCAGGCGCTGGTGCAGCACCCGCTGATCGCCGCCGTGGGC
TTCACCGGCTCGCTCAAGGGTGGGCGGGCGCTGTTCGACCTCTGCGCGCAGCGCGAGGTGCCGATCCCCTTCTTCGGCGA
ACTGGGCTCGGTCAACCCGATGTTCCTGCTGCCCGAAGCGGTGAAGGCGCGGGGCGCCGCGATCGGAACGGGCTGGGCGG
CGTCGTTGACCATGGGCGCCGGCCAGTTCTGCACCAACCCGGGCATTGCCGTGGTTGAGATCGGCCCCGAGGGCGACGCT
TTCGTCGCCGCCGCAGCCGAGGCGCTGCGCGGCGTGCCCGCCCAGTGCATGCTCACCCGCGATATCGCACAGGCCTACAG
GAAGGGCAGGTCCCGCTTCGACGGGCGCCCGGACGTGCGGCCGGTGCTGACCACCGACAGCGACGGCCGCAACGCCCTGC
CCAACCTCTTCGAGACCGATCCGGCGAGCTACCTGCGGGACCCGGCGCTTGGCGAAGAGGTCTTCGGCCCGCTCGGCCTC
GTGGTGCGGGTCTCGGGCGCGGACGAGGTGGACGCGCTTGCCCGCGGCCTCGAGGGCCAGCTCACCGCCACCATCCACAT
GGACGAGGGCGACACGGCGCTCGCACAGCGCCTGATGCCGGTGCTCGAGCGCAAGGCCGGCCGGCTGCTCGTCAACGGCT
TTCCGACGGGGGTCGAGGTCTCTCACGCCATGGTGCATGGCGGGCCTTACCCCGCCTCGACCAACTTCGGCGCGACCTCG
GTCGGCACGCTCTCGATCCGCCGCTTCCTGCGCCCGGTGAGCTACCAGAACCTGCCCCCTGCGCTGCTGCCGCGCGATCT
GGCCTGA

Upstream 100 bases:

>100_bases
GGCGTCTCGCCGCCGGCGAAAGCCTGGCCGTGCTCAACGGCTACGACACCCAGACCTGACCGCCCGCGGTCGGACGACAT
CTCAGACACGGGAGCCTTTC

Downstream 100 bases:

>100_bases
GCCCCTGCCGCTTGGCCCCGAAGGCGCTGTCGCCGGCAGCGCCTTCGGGCAGGCAGCCCGTTTCGCATGGCCGCGGCCAT
GCCCCAAACCTCTCTGCATC

Product: NAD-dependent aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDCACRAAEEAFWTYGQTTRESRAVFLRAIADEIE
ARAEAITEIGSRETGLPEARLQGERGRTTGQLRLFAEHILEGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPVAVFGAS
NFPLAFSTAGGDTAAALAAGCPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGTGWAASLTMGAGQFCTNPGIAVVEIGPEGDA
FVAAAAEALRGVPAQCMLTRDIAQAYRKGRSRFDGRPDVRPVLTTDSDGRNALPNLFETDPASYLRDPALGEEVFGPLGL
VVRVSGADEVDALARGLEGQLTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
VGTLSIRRFLRPVSYQNLPPALLPRDLA

Sequences:

>Translated_508_residues
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDCACRAAEEAFWTYGQTTRESRAVFLRAIADEIE
ARAEAITEIGSRETGLPEARLQGERGRTTGQLRLFAEHILEGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPVAVFGAS
NFPLAFSTAGGDTAAALAAGCPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGTGWAASLTMGAGQFCTNPGIAVVEIGPEGDA
FVAAAAEALRGVPAQCMLTRDIAQAYRKGRSRFDGRPDVRPVLTTDSDGRNALPNLFETDPASYLRDPALGEEVFGPLGL
VVRVSGADEVDALARGLEGQLTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
VGTLSIRRFLRPVSYQNLPPALLPRDLA
>Mature_508_residues
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDCACRAAEEAFWTYGQTTRESRAVFLRAIADEIE
ARAEAITEIGSRETGLPEARLQGERGRTTGQLRLFAEHILEGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPVAVFGAS
NFPLAFSTAGGDTAAALAAGCPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGTGWAASLTMGAGQFCTNPGIAVVEIGPEGDA
FVAAAAEALRGVPAQCMLTRDIAQAYRKGRSRFDGRPDVRPVLTTDSDGRNALPNLFETDPASYLRDPALGEEVFGPLGL
VVRVSGADEVDALARGLEGQLTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
VGTLSIRRFLRPVSYQNLPPALLPRDLA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=284, Percent_Identity=28.169014084507, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507229, Length=328, Percent_Identity=29.5731707317073, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI25777721, Length=337, Percent_Identity=28.486646884273, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI238814322, Length=370, Percent_Identity=24.8648648648649, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI115387104, Length=282, Percent_Identity=29.0780141843972, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI12007648, Length=404, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789015, Length=307, Percent_Identity=30.2931596091205, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788042, Length=424, Percent_Identity=28.3018867924528, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081896, Length=445, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787558, Length=469, Percent_Identity=26.865671641791, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786504, Length=474, Percent_Identity=27.4261603375527, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787250, Length=283, Percent_Identity=30.7420494699647, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082295, Length=308, Percent_Identity=26.2987012987013, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081926, Length=435, Percent_Identity=24.8275862068966, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995606, Length=279, Percent_Identity=31.8996415770609, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71995613, Length=279, Percent_Identity=31.8996415770609, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143874, Length=311, Percent_Identity=27.6527331189711, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25143876, Length=312, Percent_Identity=27.5641025641026, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133930964, Length=280, Percent_Identity=30, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562198, Length=448, Percent_Identity=24.7767857142857, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=445, Percent_Identity=26.5168539325843, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319478, Length=286, Percent_Identity=30.0699300699301, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323822, Length=466, Percent_Identity=24.8927038626609, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323821, Length=457, Percent_Identity=24.507658643326, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24585660, Length=394, Percent_Identity=24.6192893401015, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362580, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI62472918, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI62472926, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI62472936, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356737, Length=307, Percent_Identity=27.6872964169381, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666674, Length=249, Percent_Identity=30.1204819277108, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 53524; Mature: 53524

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDCACRAAEEAFWTY
CCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHC
GQTTRESRAVFLRAIADEIEARAEAITEIGSRETGLPEARLQGERGRTTGQLRLFAEHIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHH
EGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPVAVFGASNFPLAFSTAGGDTAAALAAG
CCCCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEECCCCCCEEEECCCCCHHHHHHCC
CPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
CCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCHHEEEC
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGTGWAASLTMGA
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCEECCCHHHHHCCCC
GQFCTNPGIAVVEIGPEGDAFVAAAAEALRGVPAQCMLTRDIAQAYRKGRSRFDGRPDVR
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVLTTDSDGRNALPNLFETDPASYLRDPALGEEVFGPLGLVVRVSGADEVDALARGLEGQ
EEEECCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHCCEEEEEEECCCCHHHHHHCCCCCC
LTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
EEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCC
VGTLSIRRFLRPVSYQNLPPALLPRDLA
HHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDTSVFTPHGKHLIAGEWVAGETSFTSDPAHGPSHAFSVGTPDLVDCACRAAEEAFWTY
CCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHC
GQTTRESRAVFLRAIADEIEARAEAITEIGSRETGLPEARLQGERGRTTGQLRLFAEHIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHH
EGGHLDRRHDVALPERQPLPRPDIRLVMRPIGPVAVFGASNFPLAFSTAGGDTAAALAAG
CCCCCCCCCCCCCCCCCCCCCCCHHEEEECCCCEEEECCCCCCEEEECCCCCHHHHHHCC
CPVVVKGHGAHPGTAEIVAEAILAAIRKTGMPDGVFSLIQGGRRDVGQALVQHPLIAAVG
CCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCHHEEEC
FTGSLKGGRALFDLCAQREVPIPFFGELGSVNPMFLLPEAVKARGAAIGTGWAASLTMGA
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCEECCCHHHHHCCCC
GQFCTNPGIAVVEIGPEGDAFVAAAAEALRGVPAQCMLTRDIAQAYRKGRSRFDGRPDVR
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PVLTTDSDGRNALPNLFETDPASYLRDPALGEEVFGPLGLVVRVSGADEVDALARGLEGQ
EEEECCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHCCEEEEEEECCCCHHHHHHCCCCCC
LTATIHMDEGDTALAQRLMPVLERKAGRLLVNGFPTGVEVSHAMVHGGPYPASTNFGATS
EEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCC
VGTLSIRRFLRPVSYQNLPPALLPRDLA
HHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]