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The map label for this gene is dapA [C]

Identifier: 77465663

GI number: 77465663

Start: 763763

End: 764668

Strand: Reverse

Name: dapA [C]

Synonym: RSP_3655

Alternate gene names: 77465663

Gene position: 764668-763763 (Counterclockwise)

Preceding gene: 77465664

Following gene: 77465660

Centisome position: 81.09

GC content: 68.54

Gene sequence:

>906_bases
ATGGACCCGCAACAGATCAAGGCGGCCCTCGGCTCCGGCCTGCTCTCCTTCCCCGTCACGCCGTTCGACGCCGAGAACAG
GTTCGCCGCCGCCCCCTACCAGAAGCACGTCGAGTGGCTGTCCGGCTTCGACGCGCCGGTTCTCTTCGCCGCGGGCGGCA
CCGGAGAGTTCTTCTCGCTGACCCCCGACGAGATCCCCGCCATCGTCAAGGCCGCCAAGGAGAGCGCCGGCAAGACCGCC
ATCGTCTCGGGCTGCGGCTACGGGACCGAGATTGCCCGGGGCATCGCGCGTTCGGTCGAGGCGGCGGGCGGCGACGGCAT
CCTGCTGCTGCCGCATTACCTGATCGACGCGCCGCAGGAAGGGCTCTACGCCCATGTCAGGGCGGTCTGCCAGGCCACCG
GCATGGGCGTCATGGTCTACAACCGCGACAATGCCGTGCTGCAGGCCGACACGCTGGCGCGGCTCTGTGACGACTGCCCG
AACCTCGTGGGCTTCAAGGACGGCACCGGCGACATCGGCCTCGTGCGCCAGATCACCGCGAAGATGGGCGACCGGCTGAC
CTATCTCGGCGGCATGCCGACGGCGGAGCTCTTTGCCGAGGCCTACCTCGGGGCGAGCTTCACCACCTACAGTTCGGCGG
TGTTCAACTTCGTTCCGGCGCTGGCCAACAAGTTCTACGCCGCGCTGCGGGCCGGGGATCGCGCCACCTGCGAGAGCATC
CTCAACAGTTTCTTCTACCCGTTCATGGAGCTCCGCTCGCGCCGCAAGGGCTATGCGGTCGCAGCGGTCAAGGCGGGCGT
GCGGCTGGTGGGCTTCGACGCGGGCCCGGTGCGGGCGCCGCTCTCGGATCTGACCGGCGAGGAGGAAGAGATCCTCAAGG
CCCTGATCGACGCGCATCGGGAATGA

Upstream 100 bases:

>100_bases
CGAAGGCGCTGTCGCCGGCAGCGCCTTCGGGCAGGCAGCCCGTTTCGCATGGCCGCGGCCATGCCCCAAACCTCTCTGCA
TCCTATCGAAAGGACCCCTC

Downstream 100 bases:

>100_bases
AATCCGGGGTGGGTCCCGCGTCCGCGGGGCTCACCGGGCCGGGTGACGATCACGGGCGGCGGCGGGGATGTGGGTCCCGA
CTCTGCGAGGCCCGCCAGGC

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDPQQIKAALGSGLLSFPVTPFDAENRFAAAPYQKHVEWLSGFDAPVLFAAGGTGEFFSLTPDEIPAIVKAAKESAGKTA
IVSGCGYGTEIARGIARSVEAAGGDGILLLPHYLIDAPQEGLYAHVRAVCQATGMGVMVYNRDNAVLQADTLARLCDDCP
NLVGFKDGTGDIGLVRQITAKMGDRLTYLGGMPTAELFAEAYLGASFTTYSSAVFNFVPALANKFYAALRAGDRATCESI
LNSFFYPFMELRSRRKGYAVAAVKAGVRLVGFDAGPVRAPLSDLTGEEEEILKALIDAHRE

Sequences:

>Translated_301_residues
MDPQQIKAALGSGLLSFPVTPFDAENRFAAAPYQKHVEWLSGFDAPVLFAAGGTGEFFSLTPDEIPAIVKAAKESAGKTA
IVSGCGYGTEIARGIARSVEAAGGDGILLLPHYLIDAPQEGLYAHVRAVCQATGMGVMVYNRDNAVLQADTLARLCDDCP
NLVGFKDGTGDIGLVRQITAKMGDRLTYLGGMPTAELFAEAYLGASFTTYSSAVFNFVPALANKFYAALRAGDRATCESI
LNSFFYPFMELRSRRKGYAVAAVKAGVRLVGFDAGPVRAPLSDLTGEEEEILKALIDAHRE
>Mature_301_residues
MDPQQIKAALGSGLLSFPVTPFDAENRFAAAPYQKHVEWLSGFDAPVLFAAGGTGEFFSLTPDEIPAIVKAAKESAGKTA
IVSGCGYGTEIARGIARSVEAAGGDGILLLPHYLIDAPQEGLYAHVRAVCQATGMGVMVYNRDNAVLQADTLARLCDDCP
NLVGFKDGTGDIGLVRQITAKMGDRLTYLGGMPTAELFAEAYLGASFTTYSSAVFNFVPALANKFYAALRAGDRATCESI
LNSFFYPFMELRSRRKGYAVAAVKAGVRLVGFDAGPVRAPLSDLTGEEEEILKALIDAHRE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 32004; Mature: 32004

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPQQIKAALGSGLLSFPVTPFDAENRFAAAPYQKHVEWLSGFDAPVLFAAGGTGEFFSL
CCHHHHHHHHCCCHHHCCCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
TPDEIPAIVKAAKESAGKTAIVSGCGYGTEIARGIARSVEAAGGDGILLLPHYLIDAPQE
CHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCC
GLYAHVRAVCQATGMGVMVYNRDNAVLQADTLARLCDDCPNLVGFKDGTGDIGLVRQITA
HHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
KMGDRLTYLGGMPTAELFAEAYLGASFTTYSSAVFNFVPALANKFYAALRAGDRATCESI
HHCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LNSFFYPFMELRSRRKGYAVAAVKAGVRLVGFDAGPVRAPLSDLTGEEEEILKALIDAHR
HHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCC
E
C
>Mature Secondary Structure
MDPQQIKAALGSGLLSFPVTPFDAENRFAAAPYQKHVEWLSGFDAPVLFAAGGTGEFFSL
CCHHHHHHHHCCCHHHCCCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
TPDEIPAIVKAAKESAGKTAIVSGCGYGTEIARGIARSVEAAGGDGILLLPHYLIDAPQE
CHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCC
GLYAHVRAVCQATGMGVMVYNRDNAVLQADTLARLCDDCPNLVGFKDGTGDIGLVRQITA
HHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
KMGDRLTYLGGMPTAELFAEAYLGASFTTYSSAVFNFVPALANKFYAALRAGDRATCESI
HHCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LNSFFYPFMELRSRRKGYAVAAVKAGVRLVGFDAGPVRAPLSDLTGEEEEILKALIDAHR
HHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA