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The map label for this gene is yhcK [H]

Identifier: 77465514

GI number: 77465514

Start: 592286

End: 593266

Strand: Direct

Name: yhcK [H]

Synonym: RSP_3513

Alternate gene names: 77465514

Gene position: 592286-593266 (Clockwise)

Preceding gene: 77465513

Following gene: 77465516

Centisome position: 62.81

GC content: 69.72

Gene sequence:

>981_bases
ATGATGCAGGACTGCGAGAAACTTCTCGACGAGCCCGGACGGCTGGCCGCCGTCCGGCGCTATGCCGTGCTCGATACGGC
GCCGGAAGAGCCGTTCGACAAGCTCACTCGGCTGGTCTGCAACGTGCTCGAGGTGCCGTATGCGGCGGTGACCCTCATCG
ACGCGGACCGCCAGTGGTTCAAGTCTCTTGTCGGTCTGAGCGGGTCCGAGGGCCCGCGCCACGAGTCCTTCTGCACCCAC
ACGATCAAGACGCGCGACCCGATGATCGTCCCCGACGCCACGCTCGATCCGAGGTTCCGGGACAGTCCGCTGGTCACGGG
GGCGGCCGGCATCCGCAGCTACCTCGGCGTTCCGCTCGAAACACCGGACGGCTACAATCTCGGGGCGCTCTGCGCCGTCG
ATACCGCCCCCCGGACCTTCAGCACCTCCCAGATCGAGATCATGAAGAGCTTCGCCTCGCTGGTTCTCGACGAGCTGGAA
CTCCGGCAGATCGCGCTCAGCGACGCGCTGACCGGCGCCATGACGCGCCGCGGCTGGCTTGCCGCGGTCGAGAAGGAGAT
GGCGCGCGGCGCGCGTCAGGGGACGCAGGCGGCCATCGTCCTCTTCGACGTCGATCACTTCAAGGCGATCAACGACACCC
ATGGACATGCGGTGGGCGATGCCGTGCTGCAGGCCCTGACGCGGCGCTGCCTGCTGCATCTGGGCCCGGCCGATGCACTG
GGACGGATCGGGGGAGAGGAGTTCGCGGTGCTGGTGCCGGACGCGGGCCTGCCCGAGGCGATGGAACTGGCAGAGCGCCT
GCGCCGCAGCTTCTCCGACGCGCCGATCGAGGTGGCGGGCCAGGCGCTCCGGGTCACCGCCAGCTTCGGGGTGCAGGGCC
TCGATGGCGACACGGGCAACGCCGGAAGCTGGCTGGCTGCCGCGGACCGGCGGCTCTACGAGGCGAAGGCGGCCGGCCGC
AACCGCTGCCACGGCGGCTGA

Upstream 100 bases:

>100_bases
GGGGCCCGGTCCCTTCGGCGATCCCGATGGCCGAACAAAATCGGCGCGGGGCGATTGTCCGCCCCGGCGGGGCGCCCGCC
GCCCTCCGTGCGTCGAGGCC

Downstream 100 bases:

>100_bases
CCGGCCGCGGCCGCGCCTTCTGCGGACCACGGCGAAGGGGTGGCAAAGGCCCCTCGGACCGGTTGCCCGCGGCCCTCGCG
AGCGTGAGGACAGTCATGAG

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MMQDCEKLLDEPGRLAAVRRYAVLDTAPEEPFDKLTRLVCNVLEVPYAAVTLIDADRQWFKSLVGLSGSEGPRHESFCTH
TIKTRDPMIVPDATLDPRFRDSPLVTGAAGIRSYLGVPLETPDGYNLGALCAVDTAPRTFSTSQIEIMKSFASLVLDELE
LRQIALSDALTGAMTRRGWLAAVEKEMARGARQGTQAAIVLFDVDHFKAINDTHGHAVGDAVLQALTRRCLLHLGPADAL
GRIGGEEFAVLVPDAGLPEAMELAERLRRSFSDAPIEVAGQALRVTASFGVQGLDGDTGNAGSWLAAADRRLYEAKAAGR
NRCHGG

Sequences:

>Translated_326_residues
MMQDCEKLLDEPGRLAAVRRYAVLDTAPEEPFDKLTRLVCNVLEVPYAAVTLIDADRQWFKSLVGLSGSEGPRHESFCTH
TIKTRDPMIVPDATLDPRFRDSPLVTGAAGIRSYLGVPLETPDGYNLGALCAVDTAPRTFSTSQIEIMKSFASLVLDELE
LRQIALSDALTGAMTRRGWLAAVEKEMARGARQGTQAAIVLFDVDHFKAINDTHGHAVGDAVLQALTRRCLLHLGPADAL
GRIGGEEFAVLVPDAGLPEAMELAERLRRSFSDAPIEVAGQALRVTASFGVQGLDGDTGNAGSWLAAADRRLYEAKAAGR
NRCHGG
>Mature_326_residues
MMQDCEKLLDEPGRLAAVRRYAVLDTAPEEPFDKLTRLVCNVLEVPYAAVTLIDADRQWFKSLVGLSGSEGPRHESFCTH
TIKTRDPMIVPDATLDPRFRDSPLVTGAAGIRSYLGVPLETPDGYNLGALCAVDTAPRTFSTSQIEIMKSFASLVLDELE
LRQIALSDALTGAMTRRGWLAAVEKEMARGARQGTQAAIVLFDVDHFKAINDTHGHAVGDAVLQALTRRCLLHLGPADAL
GRIGGEEFAVLVPDAGLPEAMELAERLRRSFSDAPIEVAGQALRVTASFGVQGLDGDTGNAGSWLAAADRRLYEAKAAGR
NRCHGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=36.5853658536585, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787262, Length=186, Percent_Identity=33.8709677419355, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788381, Length=264, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=181, Percent_Identity=36.4640883977901, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787802, Length=183, Percent_Identity=32.7868852459016, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=32.484076433121, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081977, Length=227, Percent_Identity=27.7533039647577, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=36.144578313253, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788085, Length=175, Percent_Identity=32.5714285714286, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=32.0987654320988, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=27.6729559748428, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=159, Percent_Identity=30.8176100628931, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 35108; Mature: 35108

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQDCEKLLDEPGRLAAVRRYAVLDTAPEEPFDKLTRLVCNVLEVPYAAVTLIDADRQWF
CCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHEEEEECCCHHHH
KSLVGLSGSEGPRHESFCTHTIKTRDPMIVPDATLDPRFRDSPLVTGAAGIRSYLGVPLE
HHHHCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCEECHHHHHHHHCCCCC
TPDGYNLGALCAVDTAPRTFSTSQIEIMKSFASLVLDELELRQIALSDALTGAMTRRGWL
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVEKEMARGARQGTQAAIVLFDVDHFKAINDTHGHAVGDAVLQALTRRCLLHLGPADAL
HHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
GRIGGEEFAVLVPDAGLPEAMELAERLRRSFSDAPIEVAGQALRVTASFGVQGLDGDTGN
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCHHEEEEHHCCCCCCCCCCCC
AGSWLAAADRRLYEAKAAGRNRCHGG
CCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMQDCEKLLDEPGRLAAVRRYAVLDTAPEEPFDKLTRLVCNVLEVPYAAVTLIDADRQWF
CCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHEEEEECCCHHHH
KSLVGLSGSEGPRHESFCTHTIKTRDPMIVPDATLDPRFRDSPLVTGAAGIRSYLGVPLE
HHHHCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCCEECHHHHHHHHCCCCC
TPDGYNLGALCAVDTAPRTFSTSQIEIMKSFASLVLDELELRQIALSDALTGAMTRRGWL
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVEKEMARGARQGTQAAIVLFDVDHFKAINDTHGHAVGDAVLQALTRRCLLHLGPADAL
HHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
GRIGGEEFAVLVPDAGLPEAMELAERLRRSFSDAPIEVAGQALRVTASFGVQGLDGDTGN
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCHHEEEEHHCCCCCCCCCCCC
AGSWLAAADRRLYEAKAAGRNRCHGG
CCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]