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The map label for this gene is qseC [H]

Identifier: 77465433

GI number: 77465433

Start: 501907

End: 503259

Strand: Direct

Name: qseC [H]

Synonym: RSP_3431

Alternate gene names: 77465433

Gene position: 501907-503259 (Clockwise)

Preceding gene: 77465432

Following gene: 77465434

Centisome position: 53.22

GC content: 74.21

Gene sequence:

>1353_bases
GTGAGTTCGATCCAGCGCCGCCTGTTTCTCGTCCTTCTCGCCGCCACCGGAGCGATCTGGCTCTCGGCCGCGCTCTGGGT
CCATTCCTCGACGCGGACCGAGCTGAACCGGATGCTGGACAACCGGCTGGCCGAGGCCGCGCGCATGGTGGGCAGCCTCG
TCGACGGCGACGGGCTGCCGCTCGACACGGCGATGCAGATGGCGGCCCCCGCCCTGCCCGGCGACACGGCCCACGGCTAC
GCCCACCAGCTCTCCTGTCAGGTCTGGGGACTGGACGGCACGCGGATCGCCGCCTCGTCGCAGGCCCCGGCCGAGGCGCT
CTCGACCGTCCCGCAGGGCTTCAGCGAGCACGCGGCCGAGGGCATCGTCTGGCGAGTCTACACCCATTTGGACGAAGCGC
GCGGCATCCGCGTGATGGTGGGCGACAGCCTGCGCATGCGCGAGCGGCTGCTGCACGACATGGTGCTGGGGCTCATGTGG
CCTGCGCTCGTGGTGCTGCCGCTTCTCGCCGGCGCGATCTGGCTCAGCCTGCGCAGCGGCCTTGCGCCGCTCCGGCGCAT
CACCCGCGAACTCGCGCATCGCGGGGCCGACGATCTTTCGCCCCTCCATGCGCCCGCGCCGGGCGAGGTGGCGCCGGTGG
TCGAGGCGCTGAACGGGCTCTTCCGCCGGGTGCAGGCGGCGCGCCAGCATGAGCAGGATTTCACGGCCTATGCCGCGCAC
GAGTTGAAGACCCCGCTCGCGGGCCTGAAGATGCAGGCCGAGGTGGCGAGGCGGGCGCCGGATGCCGCAACGCGCGACCA
TGCGCTGGCCCAGATCCGGCGCGCGGTCGACCGGTCGGACCGGCTGGTGCACCAGCTCCTCGACATGGCGGCGGTGGATC
AGGGCGCGGCCGAGAGCCCGCCCCGCCCGCTCGGCCGGATCGGCGCCGAGGTGCTGGAGCTGACCCTGCCCGCCGCCCGG
GCGCGCGACGTGCGGCTGACGCTCGACTGCGCGCCGGCCCTCGCCGACCGGCCGCAGCGCGATCCTGCCCTTCTGGTGGT
GGCCCTGCGCAACCTCGTCGAGAATGCGGTCCATGCCAGCGCCGAGGGCGGGCGGGTGGAGCTGGCCTTCCGGCCCGACG
GGGCGGGCTGGCGGGCCGAGATCCGCGACGAGGGCCCCGGCATTCCTCAGGACATCCGGGGACGGATCACCGAACGCTTC
TACCGCGGCCCCACCGGCGGCGAGGGCAGCGGCCTCGGACTGGCCATCGTCGAGGCGGCGGCCCGGCGGCTCGGGGCGCA
GTTCGCGCTCCGCCCGCAGAGCCCGCGCGGCGAGGTGGCGACCCTGCTCTTTCCCGCTTCCGATCTCGCCTGA

Upstream 100 bases:

>100_bases
GCAACGCGATCGAGGTCCATGTCCACAAGCTGCGTGCCAAGCTCGGGCACGGCTTCATCGAGACGGTGCGCGGCGTGGGC
TATCGGCTGGCGGAGGCCTC

Downstream 100 bases:

>100_bases
GCCGAGAGTGCGCCCTGCTGCCGCACCGCTTCGGCCGTTTCCCGGTCGGCCGGACAGGCCCTCCATCCGAAAGATCCTGT
AAATCCGTCCGATGGATGAT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSSIQRRLFLVLLAATGAIWLSAALWVHSSTRTELNRMLDNRLAEAARMVGSLVDGDGLPLDTAMQMAAPALPGDTAHGY
AHQLSCQVWGLDGTRIAASSQAPAEALSTVPQGFSEHAAEGIVWRVYTHLDEARGIRVMVGDSLRMRERLLHDMVLGLMW
PALVVLPLLAGAIWLSLRSGLAPLRRITRELAHRGADDLSPLHAPAPGEVAPVVEALNGLFRRVQAARQHEQDFTAYAAH
ELKTPLAGLKMQAEVARRAPDAATRDHALAQIRRAVDRSDRLVHQLLDMAAVDQGAAESPPRPLGRIGAEVLELTLPAAR
ARDVRLTLDCAPALADRPQRDPALLVVALRNLVENAVHASAEGGRVELAFRPDGAGWRAEIRDEGPGIPQDIRGRITERF
YRGPTGGEGSGLGLAIVEAAARRLGAQFALRPQSPRGEVATLLFPASDLA

Sequences:

>Translated_450_residues
MSSIQRRLFLVLLAATGAIWLSAALWVHSSTRTELNRMLDNRLAEAARMVGSLVDGDGLPLDTAMQMAAPALPGDTAHGY
AHQLSCQVWGLDGTRIAASSQAPAEALSTVPQGFSEHAAEGIVWRVYTHLDEARGIRVMVGDSLRMRERLLHDMVLGLMW
PALVVLPLLAGAIWLSLRSGLAPLRRITRELAHRGADDLSPLHAPAPGEVAPVVEALNGLFRRVQAARQHEQDFTAYAAH
ELKTPLAGLKMQAEVARRAPDAATRDHALAQIRRAVDRSDRLVHQLLDMAAVDQGAAESPPRPLGRIGAEVLELTLPAAR
ARDVRLTLDCAPALADRPQRDPALLVVALRNLVENAVHASAEGGRVELAFRPDGAGWRAEIRDEGPGIPQDIRGRITERF
YRGPTGGEGSGLGLAIVEAAARRLGAQFALRPQSPRGEVATLLFPASDLA
>Mature_449_residues
SSIQRRLFLVLLAATGAIWLSAALWVHSSTRTELNRMLDNRLAEAARMVGSLVDGDGLPLDTAMQMAAPALPGDTAHGYA
HQLSCQVWGLDGTRIAASSQAPAEALSTVPQGFSEHAAEGIVWRVYTHLDEARGIRVMVGDSLRMRERLLHDMVLGLMWP
ALVVLPLLAGAIWLSLRSGLAPLRRITRELAHRGADDLSPLHAPAPGEVAPVVEALNGLFRRVQAARQHEQDFTAYAAHE
LKTPLAGLKMQAEVARRAPDAATRDHALAQIRRAVDRSDRLVHQLLDMAAVDQGAAESPPRPLGRIGAEVLELTLPAARA
RDVRLTLDCAPALADRPQRDPALLVVALRNLVENAVHASAEGGRVELAFRPDGAGWRAEIRDEGPGIPQDIRGRITERFY
RGPTGGEGSGLGLAIVEAAARRLGAQFALRPQSPRGEVATLLFPASDLA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=438, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1790551, Length=290, Percent_Identity=32.0689655172414, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=291, Percent_Identity=26.4604810996564, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=28.7162162162162, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=29.7520661157025, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=28.0701754385965, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=30.0429184549356, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=27.8884462151394, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=25.3333333333333, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=23.2067510548523, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=28, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=228, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48405; Mature: 48274

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIQRRLFLVLLAATGAIWLSAALWVHSSTRTELNRMLDNRLAEAARMVGSLVDGDGLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDTAMQMAAPALPGDTAHGYAHQLSCQVWGLDGTRIAASSQAPAEALSTVPQGFSEHAAE
HHHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCEEECCCCCHHHHHHHHHCCHHHHHHC
GIVWRVYTHLDEARGIRVMVGDSLRMRERLLHDMVLGLMWPALVVLPLLAGAIWLSLRSG
CHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAPLRRITRELAHRGADDLSPLHAPAPGEVAPVVEALNGLFRRVQAARQHEQDFTAYAAH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKTPLAGLKMQAEVARRAPDAATRDHALAQIRRAVDRSDRLVHQLLDMAAVDQGAAESP
HHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRPLGRIGAEVLELTLPAARARDVRLTLDCAPALADRPQRDPALLVVALRNLVENAVHAS
CCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
AEGGRVELAFRPDGAGWRAEIRDEGPGIPQDIRGRITERFYRGPTGGEGSGLGLAIVEAA
CCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ARRLGAQFALRPQSPRGEVATLLFPASDLA
HHHHCCCEEECCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SSIQRRLFLVLLAATGAIWLSAALWVHSSTRTELNRMLDNRLAEAARMVGSLVDGDGLP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDTAMQMAAPALPGDTAHGYAHQLSCQVWGLDGTRIAASSQAPAEALSTVPQGFSEHAAE
HHHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCEEECCCCCHHHHHHHHHCCHHHHHHC
GIVWRVYTHLDEARGIRVMVGDSLRMRERLLHDMVLGLMWPALVVLPLLAGAIWLSLRSG
CHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LAPLRRITRELAHRGADDLSPLHAPAPGEVAPVVEALNGLFRRVQAARQHEQDFTAYAAH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKTPLAGLKMQAEVARRAPDAATRDHALAQIRRAVDRSDRLVHQLLDMAAVDQGAAESP
HHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRPLGRIGAEVLELTLPAARARDVRLTLDCAPALADRPQRDPALLVVALRNLVENAVHAS
CCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
AEGGRVELAFRPDGAGWRAEIRDEGPGIPQDIRGRITERFYRGPTGGEGSGLGLAIVEAA
CCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ARRLGAQFALRPQSPRGEVATLLFPASDLA
HHHHCCCEEECCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]