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The map label for this gene is tar [H]

Identifier: 77465434

GI number: 77465434

Start: 503437

End: 504996

Strand: Direct

Name: tar [H]

Synonym: RSP_3432

Alternate gene names: 77465434

Gene position: 503437-504996 (Clockwise)

Preceding gene: 77465433

Following gene: 77465435

Centisome position: 53.39

GC content: 71.35

Gene sequence:

>1560_bases
ATGAGGGTGACGATCAGAACCAAACTGGCCGCGGCATTCACCGTGGTTTTCGTCATGGCGGGGTTGGCGGTGGCGCTCGC
CCTGGTCCAACTGGGGCGTGTCGACCAGCGCATGACCGAGGTCATCGACGAGCATGTGCAGGAGGTGGTGCTCGCCCAGC
GGCTCAGCATCGGGCAGTATCGCGTGATGGCCAGCATCCGCGCGCATCTGCTCGACCGGGACTCGGACTCCGCGATCCAG
ATCGAGACGAGCGTGCAGGAGGGCCGGATGATCCAGCGCCGCGCCCTGCGTGCCCTGCGCGACAGACCGCAGGATGCGGC
GACAGCCGATCTCCTGATCCGCTACAACGATCTCAGGAAGCAGATCCAGCGGGTGAACAACCGCGCCATGATCCTGTCGC
TCGGGGGCAACCCGCAGGGCGCGGCCGCCTTCCTCCGCGAGGCGGGCGCGGCCGGCCTCGAACGGTCGCTCGAGGGCCTG
TCCGAAGATCTGGTAACCCACAAGCTCGAGCTTCTCGAGCGTGAGAAGGCCGAGGCGAATGCCGAAGGGCGCTCCGTGCT
GGCGCTCGTGATGCTGATCGGGGCCCTGTCCGCAGTCGTGGGCTCGGCAGCGGCGATCTGGATCACGCTCTCGATCGGCC
GCGGGCTTCGCCGGGCCCTCGCACTCACGCGGCGGGTCGCGGCCGGCGACCTCACGGAGGGCGAAGAGGTCAAGGGACGC
GACGAGATCGCCGATCTGCTCGGTGCCAGCAACCGGATGCTCGAGAAGCTGCGCGAGGTGATGGACGAAGTGTCGGGCAC
CGCCCGCGATGTGGCGGCGGCGAGCGGCCGGATGGCCACGGCCGCCGGGCAGCTCAAGTCCGGCACGGAAGAGCAGGCCT
CGGCCACAGTCGAGGCCTCGGCCGCGGTCGAGCAGATGGTGGGCAACATCACCCAGTCCGAGAGCAATGCCGGCGTCACC
GCGCAGATCGCGGGCTCCTCGGCGGACGATGCGCGGCGCTGCGGCGTGGCGGTGGCCGAGGCCGTGCGGTCGATGCAGGA
GATCGCCGAGCGGATCGGCGTGGTCCGCGAGATCGCCCGGCAGACCGACCTTCTGGCGCTGAATGCGGCCGTCGAGGCCG
CGCGGGCGGGTGAGCAGGGACGCGGCTTTGCCGTCGTCGCGGCCGAGGTGCGGCGGCTCGCCGAACGCAGCGCCGAGGCC
GCGGCCGAGATCTCGACCCTCTCCGCCGGGACGGCGCGGGCCGCGGCCGGGGCCGGCGAGATGATCGACCGGCTGGTGCC
CGAGATCGAGCGCACGTCGGAGCTCGTCACCGACATCTCGGTCGCCTCGCGCGAGCTGTCCGAGGGCGCGCGGCAGGTCT
CGCTCGCCATCGATGCGCTCGACCGGGTGACGCAGCAGACCGATGCGGCCTCGAAGCTGCTCGACGAGGATGCGGAGGAT
CTGGCGGCGCGGGCCCGGCGGCTTCTGACCAGCGCGACCTACTTCCGCACCGGACCCGCGACCGAAGGCGGTGAGGCAGA
AGAGGCCGCGGCCCCCGAGGACTGGCGCGCCGTGGCCTGA

Upstream 100 bases:

>100_bases
TGTAAATCCGTCCGATGGATGATGCCCGCCACCGGCGCCAAGGTCTATGGGTTCCGCAGTGGCTTCCGGCGCAGCAACCA
TGCGCGAAAGGGATGGATGT

Downstream 100 bases:

>100_bases
CCCGCGCCGTTGTCGTGGGGGGCGGGCGCGGCTAGGCTTGCGGCAAGTCTCAGGAGAGCGCCGCATGATCCGCACGACCA
TCACCCTCGACGAGGAACTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-II; Aspartate chemoreceptor protein [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MRVTIRTKLAAAFTVVFVMAGLAVALALVQLGRVDQRMTEVIDEHVQEVVLAQRLSIGQYRVMASIRAHLLDRDSDSAIQ
IETSVQEGRMIQRRALRALRDRPQDAATADLLIRYNDLRKQIQRVNNRAMILSLGGNPQGAAAFLREAGAAGLERSLEGL
SEDLVTHKLELLEREKAEANAEGRSVLALVMLIGALSAVVGSAAAIWITLSIGRGLRRALALTRRVAAGDLTEGEEVKGR
DEIADLLGASNRMLEKLREVMDEVSGTARDVAAASGRMATAAGQLKSGTEEQASATVEASAAVEQMVGNITQSESNAGVT
AQIAGSSADDARRCGVAVAEAVRSMQEIAERIGVVREIARQTDLLALNAAVEAARAGEQGRGFAVVAAEVRRLAERSAEA
AAEISTLSAGTARAAAGAGEMIDRLVPEIERTSELVTDISVASRELSEGARQVSLAIDALDRVTQQTDAASKLLDEDAED
LAARARRLLTSATYFRTGPATEGGEAEEAAAPEDWRAVA

Sequences:

>Translated_519_residues
MRVTIRTKLAAAFTVVFVMAGLAVALALVQLGRVDQRMTEVIDEHVQEVVLAQRLSIGQYRVMASIRAHLLDRDSDSAIQ
IETSVQEGRMIQRRALRALRDRPQDAATADLLIRYNDLRKQIQRVNNRAMILSLGGNPQGAAAFLREAGAAGLERSLEGL
SEDLVTHKLELLEREKAEANAEGRSVLALVMLIGALSAVVGSAAAIWITLSIGRGLRRALALTRRVAAGDLTEGEEVKGR
DEIADLLGASNRMLEKLREVMDEVSGTARDVAAASGRMATAAGQLKSGTEEQASATVEASAAVEQMVGNITQSESNAGVT
AQIAGSSADDARRCGVAVAEAVRSMQEIAERIGVVREIARQTDLLALNAAVEAARAGEQGRGFAVVAAEVRRLAERSAEA
AAEISTLSAGTARAAAGAGEMIDRLVPEIERTSELVTDISVASRELSEGARQVSLAIDALDRVTQQTDAASKLLDEDAED
LAARARRLLTSATYFRTGPATEGGEAEEAAAPEDWRAVA
>Mature_519_residues
MRVTIRTKLAAAFTVVFVMAGLAVALALVQLGRVDQRMTEVIDEHVQEVVLAQRLSIGQYRVMASIRAHLLDRDSDSAIQ
IETSVQEGRMIQRRALRALRDRPQDAATADLLIRYNDLRKQIQRVNNRAMILSLGGNPQGAAAFLREAGAAGLERSLEGL
SEDLVTHKLELLEREKAEANAEGRSVLALVMLIGALSAVVGSAAAIWITLSIGRGLRRALALTRRVAAGDLTEGEEVKGR
DEIADLLGASNRMLEKLREVMDEVSGTARDVAAASGRMATAAGQLKSGTEEQASATVEASAAVEQMVGNITQSESNAGVT
AQIAGSSADDARRCGVAVAEAVRSMQEIAERIGVVREIARQTDLLALNAAVEAARAGEQGRGFAVVAAEVRRLAERSAEA
AAEISTLSAGTARAAAGAGEMIDRLVPEIERTSELVTDISVASRELSEGARQVSLAIDALDRVTQQTDAASKLLDEDAED
LAARARRLLTSATYFRTGPATEGGEAEEAAAPEDWRAVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=296, Percent_Identity=38.5135135135135, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI1788195, Length=266, Percent_Identity=40.6015037593985, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=33.7988826815642, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1788194, Length=330, Percent_Identity=35.4545454545455, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789453, Length=305, Percent_Identity=30.1639344262295, Blast_Score=123, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55016; Mature: 55016

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTIRTKLAAAFTVVFVMAGLAVALALVQLGRVDQRMTEVIDEHVQEVVLAQRLSIGQY
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RVMASIRAHLLDRDSDSAIQIETSVQEGRMIQRRALRALRDRPQDAATADLLIRYNDLRK
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QIQRVNNRAMILSLGGNPQGAAAFLREAGAAGLERSLEGLSEDLVTHKLELLEREKAEAN
HHHHHCCCEEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEGRSVLALVMLIGALSAVVGSAAAIWITLSIGRGLRRALALTRRVAAGDLTEGEEVKGR
CCHHHHHHHHHHHHHHHHHHHCHHHHEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DEIADLLGASNRMLEKLREVMDEVSGTARDVAAASGRMATAAGQLKSGTEEQASATVEAS
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
AAVEQMVGNITQSESNAGVTAQIAGSSADDARRCGVAVAEAVRSMQEIAERIGVVREIAR
HHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTDLLALNAAVEAARAGEQGRGFAVVAAEVRRLAERSAEAAAEISTLSAGTARAAAGAGE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
MIDRLVPEIERTSELVTDISVASRELSEGARQVSLAIDALDRVTQQTDAASKLLDEDAED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LAARARRLLTSATYFRTGPATEGGEAEEAAAPEDWRAVA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MRVTIRTKLAAAFTVVFVMAGLAVALALVQLGRVDQRMTEVIDEHVQEVVLAQRLSIGQY
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RVMASIRAHLLDRDSDSAIQIETSVQEGRMIQRRALRALRDRPQDAATADLLIRYNDLRK
HHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QIQRVNNRAMILSLGGNPQGAAAFLREAGAAGLERSLEGLSEDLVTHKLELLEREKAEAN
HHHHHCCCEEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEGRSVLALVMLIGALSAVVGSAAAIWITLSIGRGLRRALALTRRVAAGDLTEGEEVKGR
CCHHHHHHHHHHHHHHHHHHHCHHHHEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DEIADLLGASNRMLEKLREVMDEVSGTARDVAAASGRMATAAGQLKSGTEEQASATVEAS
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHH
AAVEQMVGNITQSESNAGVTAQIAGSSADDARRCGVAVAEAVRSMQEIAERIGVVREIAR
HHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTDLLALNAAVEAARAGEQGRGFAVVAAEVRRLAERSAEAAAEISTLSAGTARAAAGAGE
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHH
MIDRLVPEIERTSELVTDISVASRELSEGARQVSLAIDALDRVTQQTDAASKLLDEDAED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LAARARRLLTSATYFRTGPATEGGEAEEAAAPEDWRAVA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6302843; 11677609; 1660187; 8486661; 8831788 [H]