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The map label for this gene is dppC [H]

Identifier: 77465245

GI number: 77465245

Start: 292202

End: 293104

Strand: Direct

Name: dppC [H]

Synonym: RSP_3233

Alternate gene names: 77465245

Gene position: 292202-293104 (Clockwise)

Preceding gene: 77465244

Following gene: 77465246

Centisome position: 30.99

GC content: 68.22

Gene sequence:

>903_bases
ATGACCGACGTGACAAAGCCCGTTTCGCAGGGCTCGGAAACGAAGCGCCTGCTGCGCGAGTTCTGGTTCTACTTCTCCGA
GAACCGTGGTGCCGTGATCGGCCTCTGCGTCTTCCTCGCGCTCGTGCTGATCGCGGCCTTCGCCCCGCTGCTCGCGCCGC
ACAGCCCGACGCTCCAGAACCGCGACGCGCTGCTCGTGCCGCCGTTCTGGGAGCAGGGCGGCAACCCGAGCTTCCTTCTC
GGCACCGATGCGGTCGGCCGCGACATCCTCTCGCGGCTGATCTTCGGCGCGCGGCAGTCGCTCTTCATCGGCTGTGTGGT
GGTCTCGATCGCGCTCACGGGCGGCATCATCCTCGGCCTCGTTGCGGGCTTCTTCGGCGGATGGGTGGATGCGGTCATCA
TGCGGGTGATGGATGTGATCCTGGCCTTCCCGTCGCTGCTCCTCGCGCTCGTGATGGTGGCGATCCTCGGGCCGGGGCTG
ACCAACGCGATGATCGCCATTGCCATCGTGCTGCAGCCCCACTTCGCGCGGCTCACGCGGGCGGCGGTGATGGCCGAGAA
GAACCGCGAATATGTCATGGCCGCGCGCGTGGCCGGGGCAGGGCGCCTGCGGCTGATGTTCCGCACCATCCTGCCCAACT
GCCTCGCGCCGCTGATCGTGCAGGGGACGCTCTCCTTCTCGAATGCCGTGCTCGACGCGGCGGCGCTCGGCTTCCTCGGC
ATGGGCGCGCAGCCGCCGACCCCCGAATGGGGCACGATGCTTGCCGAAGCGCGCGAGTTCATCCTGCGCGCCTGGTGGGT
GGTGACTTTCCCCGGTCTCGCGATCCTCATCACCGTGCTCGCGATCAACCTCGTGGGCGACGGGCTGCGCGACGCGCTCG
ACCCGAAACTGAAGCGGAGCTGA

Upstream 100 bases:

>100_bases
GGCCTGCTGCTCATGGCGGGCGTCGTGATGCTGGTCAACCTGATCGTCGATCTCCTCTACGGGGTCATCAACCCCCGCAT
CCGTCATTCGTGAGGGCTCC

Downstream 100 bases:

>100_bases
GCCGATGGCGCTACTCGAAATCCGCAACCTCTCCGTCAGCTTCGCCACCTCGACCGGCCGCTTCCATGCCGTGCGGGGCA
TCGACATGACCGTCAACAGC

Product: ABC peptide transporter, inner membrane subunit

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTDVTKPVSQGSETKRLLREFWFYFSENRGAVIGLCVFLALVLIAAFAPLLAPHSPTLQNRDALLVPPFWEQGGNPSFLL
GTDAVGRDILSRLIFGARQSLFIGCVVVSIALTGGIILGLVAGFFGGWVDAVIMRVMDVILAFPSLLLALVMVAILGPGL
TNAMIAIAIVLQPHFARLTRAAVMAEKNREYVMAARVAGAGRLRLMFRTILPNCLAPLIVQGTLSFSNAVLDAAALGFLG
MGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLVGDGLRDALDPKLKRS

Sequences:

>Translated_300_residues
MTDVTKPVSQGSETKRLLREFWFYFSENRGAVIGLCVFLALVLIAAFAPLLAPHSPTLQNRDALLVPPFWEQGGNPSFLL
GTDAVGRDILSRLIFGARQSLFIGCVVVSIALTGGIILGLVAGFFGGWVDAVIMRVMDVILAFPSLLLALVMVAILGPGL
TNAMIAIAIVLQPHFARLTRAAVMAEKNREYVMAARVAGAGRLRLMFRTILPNCLAPLIVQGTLSFSNAVLDAAALGFLG
MGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLVGDGLRDALDPKLKRS
>Mature_299_residues
TDVTKPVSQGSETKRLLREFWFYFSENRGAVIGLCVFLALVLIAAFAPLLAPHSPTLQNRDALLVPPFWEQGGNPSFLLG
TDAVGRDILSRLIFGARQSLFIGCVVVSIALTGGIILGLVAGFFGGWVDAVIMRVMDVILAFPSLLLALVMVAILGPGLT
NAMIAIAIVLQPHFARLTRAAVMAEKNREYVMAARVAGAGRLRLMFRTILPNCLAPLIVQGTLSFSNAVLDAAALGFLGM
GAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLVGDGLRDALDPKLKRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=63, Blast_Score=329, Evalue=1e-91,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=46.0377358490566, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=41.9795221843003, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1787549, Length=276, Percent_Identity=43.1159420289855, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=40, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=32.3529411764706, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=26.605504587156, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32236; Mature: 32105

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVTKPVSQGSETKRLLREFWFYFSENRGAVIGLCVFLALVLIAAFAPLLAPHSPTLQN
CCCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDALLVPPFWEQGGNPSFLLGTDAVGRDILSRLIFGARQSLFIGCVVVSIALTGGIILGL
CCCEEECCHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGFFGGWVDAVIMRVMDVILAFPSLLLALVMVAILGPGLTNAMIAIAIVLQPHFARLTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AAVMAEKNREYVMAARVAGAGRLRLMFRTILPNCLAPLIVQGTLSFSNAVLDAAALGFLG
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MGAQPPTPEWGTMLAEAREFILRAWWVVTFPGLAILITVLAINLVGDGLRDALDPKLKRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDVTKPVSQGSETKRLLREFWFYFSENRGAVIGLCVFLALVLIAAFAPLLAPHSPTLQN
CCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]