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The map label for this gene is betT [H]

Identifier: 77461462

GI number: 77461462

Start: 5897261

End: 5899258

Strand: Reverse

Name: betT [H]

Synonym: Pfl01_5241

Alternate gene names: 77461462

Gene position: 5899258-5897261 (Counterclockwise)

Preceding gene: 77461472

Following gene: 77461458

Centisome position: 91.63

GC content: 60.76

Gene sequence:

>1998_bases
ATGAGTTCTGCCTCGCTAATAAAGACCCCGCCCGAGAAGGTGACGGTCAACGGTTGGGTGTTCTACACCTCTACCGCGCT
GATTCTGTTGTTGACCGCCATTCTGATCATCGCCCCGCAAGAGGCCGGCAGAATGCTGGGAGTGGCTCAGGCCTGGTTGT
CCCGCAGCTTCGGCTGGTACTACATGGTGGTGATCGCCGCTTACCTGGTGTTTGTGGTGGGCTTGGCGTTTTCCTCGTAC
GGCAAACTCAAACTGGGTAGCAAGGACGACACCCCGGATTTCAGCTACGGCGCCTGGGCCGGGATGCTGTTCTCGTCGGG
TATCGGTATTTCGCTGCTGTACTTTGGCGCCTCCGAGCCACTGGATCACTACTTCAATCCGCCGGAAGGCGCGTCGGCCA
CCAACATGGCGGCACGTCAGGCTGTTCAGCTGACTTTCCTGCACTGGGGCCTGCACGGCTGGGCGATCTACGCACTGGTC
GGTCTGGCCGTGGCCTATTTCGCTTACCGTCATAACCAGCCGCTGGCCCTGCGTTCGGCGCTGTACCCGCTGGTGGGCGA
GCGTTGGGTCAAGGGCGCTGCCGGTCATGCGGTGGACGGCTTCGGCATGTTCGTGACCCTGCTGGGTCTGGTGACCAACC
TGGGGATCGGCTCGCTGCAAGTGTCCTCGGGCCTGGAAAACCTGTTCGGCATGGAACACAGCAACACCAACCTGCTGATC
GTGATCATCGTGATGAGCACAGTGGCGACCATCGCTGCCGTGTCCGGCGTGGAAAACGGTATCCGTCGTCTGTCCAACCT
CAACATCATCCTGTTCAGCGGCCTGCTGATTTTCGTCCTGCTGTTCGGCCCGACCCTGCATTTGCTCAACGGCTTCGTGC
AGAACATCGGCGACTACCTCAACGGCGTGGTGCTGAAGACTTTCGACCTGTACGTCTATGAAGGCGACAGCGAGAAGTCC
GACCGCTGGCTGGGCCTGTGGACGCTGTTCTACTGGGCCTGGTGGATTTCTTGGGCCCCATTCGTCGGCATGTTCATCGC
GCGGATTTCCCGTGGTCGTACCGTGCGTGAACTGGTGGCTGGCGTGCTGCTGATTCCGCTGGGTTTCACCCTGGCGTGGC
TGTCGATCTTCGGTAACTCGGCGCTGGATCTGGTGATGAACCAGGGCGCGGTGGAACTCGGCAAGACGGCGCTGGAACAG
CCGTCGATGGCGATCTATCAGTTGCTGGAACACTACCCGGCGTCGAAAGTCGTGATCGGTGTTTCGATCTTCGTTGGTTT
CGTGCTGTTCCTGACCCCGGCCGACTCCGGCGCGGTGATGATGGCGAACCTGTCCTGCAAGGGCGGCAACGTCGACGAAG
ACGCCCCGCACTGGCTGCGGATCTTCTGGTCGGTCGTGATCACGCTGGTGACCATCGGCCTGCTGTTCGCCGGTAACTTC
GAAGCCATGCAGACCATGGTGGTGCTGGCCGGTCTGCCGTTCTCGGTGGTGCTGGTGTGCTTCATGTTCGGCCTGCACAA
GGCGATGCGCCAGGACATGCAGATCGAACAGGAACAGGCGCAACTGGCTGAACGCGGTCGTCGTGGTTTCAGCGAGCGCC
TGACCCAGCTGGATCTGCAACCGAGCCAGTCGGTGGTTCAGCGCTTCATGGACAAACACGTCAGCCCGGCACTGGAAGAT
GCCGCTGCGCAAATGCGTGCACAGGGTCTGGAAGTGCAGACGCTGCTGGGCAAATCCAAGCGCTGCATGGGCGTGCGGGT
CGAGATGGAAGAGGGCAACCCTTTTGTCTACGAAGTGAGCCTGGACGGCTACCTGGCGACCCCGAGCGAGTCGGTTCAGT
CCGATGAAGCGCGCCAGCGTTTCTATCGCGCCGAGGTGTACCTGCACAACGGCAGCCAGGACTACGACCTGATGGGCTTC
ACACAGGATCAGATCACACGCGATGTGCTCGATCAGTTTGAAAGCCATCGGCAGCTCCTTGGCCGGGTCTATAGCTGA

Upstream 100 bases:

>100_bases
GTGTCTTTATATCACCCGCCGGTCGGCTGCCAACTAACCGATTGGTCGGGTTCCGTGTTGCCTTGTGTTCTTCTCTCGCA
CTGCCTGGAGCATTTGTGCC

Downstream 100 bases:

>100_bases
GTTGTGAAGTGATCAATCCCACGCGATGCGTGGGAATGATGAAAACAAAAACGCCGCGATCCTCTCGCGGCGTTTTTGTG
TCTGCTCTCTTTACCCTAGG

Product: BCCT transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MSSASLIKTPPEKVTVNGWVFYTSTALILLLTAILIIAPQEAGRMLGVAQAWLSRSFGWYYMVVIAAYLVFVVGLAFSSY
GKLKLGSKDDTPDFSYGAWAGMLFSSGIGISLLYFGASEPLDHYFNPPEGASATNMAARQAVQLTFLHWGLHGWAIYALV
GLAVAYFAYRHNQPLALRSALYPLVGERWVKGAAGHAVDGFGMFVTLLGLVTNLGIGSLQVSSGLENLFGMEHSNTNLLI
VIIVMSTVATIAAVSGVENGIRRLSNLNIILFSGLLIFVLLFGPTLHLLNGFVQNIGDYLNGVVLKTFDLYVYEGDSEKS
DRWLGLWTLFYWAWWISWAPFVGMFIARISRGRTVRELVAGVLLIPLGFTLAWLSIFGNSALDLVMNQGAVELGKTALEQ
PSMAIYQLLEHYPASKVVIGVSIFVGFVLFLTPADSGAVMMANLSCKGGNVDEDAPHWLRIFWSVVITLVTIGLLFAGNF
EAMQTMVVLAGLPFSVVLVCFMFGLHKAMRQDMQIEQEQAQLAERGRRGFSERLTQLDLQPSQSVVQRFMDKHVSPALED
AAAQMRAQGLEVQTLLGKSKRCMGVRVEMEEGNPFVYEVSLDGYLATPSESVQSDEARQRFYRAEVYLHNGSQDYDLMGF
TQDQITRDVLDQFESHRQLLGRVYS

Sequences:

>Translated_665_residues
MSSASLIKTPPEKVTVNGWVFYTSTALILLLTAILIIAPQEAGRMLGVAQAWLSRSFGWYYMVVIAAYLVFVVGLAFSSY
GKLKLGSKDDTPDFSYGAWAGMLFSSGIGISLLYFGASEPLDHYFNPPEGASATNMAARQAVQLTFLHWGLHGWAIYALV
GLAVAYFAYRHNQPLALRSALYPLVGERWVKGAAGHAVDGFGMFVTLLGLVTNLGIGSLQVSSGLENLFGMEHSNTNLLI
VIIVMSTVATIAAVSGVENGIRRLSNLNIILFSGLLIFVLLFGPTLHLLNGFVQNIGDYLNGVVLKTFDLYVYEGDSEKS
DRWLGLWTLFYWAWWISWAPFVGMFIARISRGRTVRELVAGVLLIPLGFTLAWLSIFGNSALDLVMNQGAVELGKTALEQ
PSMAIYQLLEHYPASKVVIGVSIFVGFVLFLTPADSGAVMMANLSCKGGNVDEDAPHWLRIFWSVVITLVTIGLLFAGNF
EAMQTMVVLAGLPFSVVLVCFMFGLHKAMRQDMQIEQEQAQLAERGRRGFSERLTQLDLQPSQSVVQRFMDKHVSPALED
AAAQMRAQGLEVQTLLGKSKRCMGVRVEMEEGNPFVYEVSLDGYLATPSESVQSDEARQRFYRAEVYLHNGSQDYDLMGF
TQDQITRDVLDQFESHRQLLGRVYS
>Mature_664_residues
SSASLIKTPPEKVTVNGWVFYTSTALILLLTAILIIAPQEAGRMLGVAQAWLSRSFGWYYMVVIAAYLVFVVGLAFSSYG
KLKLGSKDDTPDFSYGAWAGMLFSSGIGISLLYFGASEPLDHYFNPPEGASATNMAARQAVQLTFLHWGLHGWAIYALVG
LAVAYFAYRHNQPLALRSALYPLVGERWVKGAAGHAVDGFGMFVTLLGLVTNLGIGSLQVSSGLENLFGMEHSNTNLLIV
IIVMSTVATIAAVSGVENGIRRLSNLNIILFSGLLIFVLLFGPTLHLLNGFVQNIGDYLNGVVLKTFDLYVYEGDSEKSD
RWLGLWTLFYWAWWISWAPFVGMFIARISRGRTVRELVAGVLLIPLGFTLAWLSIFGNSALDLVMNQGAVELGKTALEQP
SMAIYQLLEHYPASKVVIGVSIFVGFVLFLTPADSGAVMMANLSCKGGNVDEDAPHWLRIFWSVVITLVTIGLLFAGNFE
AMQTMVVLAGLPFSVVLVCFMFGLHKAMRQDMQIEQEQAQLAERGRRGFSERLTQLDLQPSQSVVQRFMDKHVSPALEDA
AAQMRAQGLEVQTLLGKSKRCMGVRVEMEEGNPFVYEVSLDGYLATPSESVQSDEARQRFYRAEVYLHNGSQDYDLMGFT
QDQITRDVLDQFESHRQLLGRVYS

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=656, Percent_Identity=41.0060975609756, Blast_Score=517, Evalue=1e-147,
Organism=Escherichia coli, GI1788102, Length=460, Percent_Identity=31.9565217391304, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1786224, Length=515, Percent_Identity=26.2135922330097, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 73382; Mature: 73251

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASLIKTPPEKVTVNGWVFYTSTALILLLTAILIIAPQEAGRMLGVAQAWLSRSFGWY
CCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
YMVVIAAYLVFVVGLAFSSYGKLKLGSKDDTPDFSYGAWAGMLFSSGIGISLLYFGASEP
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
LDHYFNPPEGASATNMAARQAVQLTFLHWGLHGWAIYALVGLAVAYFAYRHNQPLALRSA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LYPLVGERWVKGAAGHAVDGFGMFVTLLGLVTNLGIGSLQVSSGLENLFGMEHSNTNLLI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEE
VIIVMSTVATIAAVSGVENGIRRLSNLNIILFSGLLIFVLLFGPTLHLLNGFVQNIGDYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NGVVLKTFDLYVYEGDSEKSDRWLGLWTLFYWAWWISWAPFVGMFIARISRGRTVRELVA
CCHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GVLLIPLGFTLAWLSIFGNSALDLVMNQGAVELGKTALEQPSMAIYQLLEHYPASKVVIG
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
VSIFVGFVLFLTPADSGAVMMANLSCKGGNVDEDAPHWLRIFWSVVITLVTIGLLFAGNF
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
EAMQTMVVLAGLPFSVVLVCFMFGLHKAMRQDMQIEQEQAQLAERGRRGFSERLTQLDLQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
PSQSVVQRFMDKHVSPALEDAAAQMRAQGLEVQTLLGKSKRCMGVRVEMEEGNPFVYEVS
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEEECCCCEEEEEE
LDGYLATPSESVQSDEARQRFYRAEVYLHNGSQDYDLMGFTQDQITRDVLDQFESHRQLL
ECCEEECCCHHHCHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GRVYS
HHHCC
>Mature Secondary Structure 
SSASLIKTPPEKVTVNGWVFYTSTALILLLTAILIIAPQEAGRMLGVAQAWLSRSFGWY
CCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
YMVVIAAYLVFVVGLAFSSYGKLKLGSKDDTPDFSYGAWAGMLFSSGIGISLLYFGASEP
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
LDHYFNPPEGASATNMAARQAVQLTFLHWGLHGWAIYALVGLAVAYFAYRHNQPLALRSA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LYPLVGERWVKGAAGHAVDGFGMFVTLLGLVTNLGIGSLQVSSGLENLFGMEHSNTNLLI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEE
VIIVMSTVATIAAVSGVENGIRRLSNLNIILFSGLLIFVLLFGPTLHLLNGFVQNIGDYL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NGVVLKTFDLYVYEGDSEKSDRWLGLWTLFYWAWWISWAPFVGMFIARISRGRTVRELVA
CCHHEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GVLLIPLGFTLAWLSIFGNSALDLVMNQGAVELGKTALEQPSMAIYQLLEHYPASKVVIG
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
VSIFVGFVLFLTPADSGAVMMANLSCKGGNVDEDAPHWLRIFWSVVITLVTIGLLFAGNF
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
EAMQTMVVLAGLPFSVVLVCFMFGLHKAMRQDMQIEQEQAQLAERGRRGFSERLTQLDLQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
PSQSVVQRFMDKHVSPALEDAAAQMRAQGLEVQTLLGKSKRCMGVRVEMEEGNPFVYEVS
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEEECCCCEEEEEE
LDGYLATPSESVQSDEARQRFYRAEVYLHNGSQDYDLMGFTQDQITRDVLDQFESHRQLL
ECCEEECCCHHHCHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GRVYS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]