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The map label for this gene is sdaA [H]

Identifier: 77461458

GI number: 77461458

Start: 5892324

End: 5893700

Strand: Reverse

Name: sdaA [H]

Synonym: Pfl01_5237

Alternate gene names: 77461458

Gene position: 5893700-5892324 (Counterclockwise)

Preceding gene: 77461462

Following gene: 77461457

Centisome position: 91.54

GC content: 63.69

Gene sequence:

>1377_bases
ATGGCTATCAGCGTTTTCGACCTGTTCAAAATCGGCATTGGCCCGTCCAGTTCCCACACCGTCGGGCCCATGCGCGCCGC
CGCCCTGTTCGTCGAGTCGTTGCGCGACAAACATCTACTGGAGCAGGTGCGTCGCATCGAGGTGCAGCTGTTCGGCTCGC
TGTCGGCCACCGGTGTCGGTCACGGCAGCGACAACGCGGTGATCATGGGCCTGATGGGCGAGTGGCCGGACGCGATCGAC
CCGTCGCAGATCGGCCCGCGGATCCAGGCCCTGCGCGAAACCCACACGCTGTTGCTCGACGGTCGTTTGTCGGTGCCCTT
TATATGGGGCCGCGACATGCGCCTGATCGACGAAAACCTGCCGTTTCACCCTAACGCCATGACCCTGGTTGCCGAAGGCG
ATCGCGGCGAGCTGCATCGCGACACCTACTATTCGGTCGGCGGCGGTTTTGTGGTGGACGAGGCGCAGGCTTCCAGTGGT
GTGGTGGATCTGGATCGCACCGAGTTGCCTTACGATTTTTCCAGCGCGGTGGAGTTGCTGGAGCTGTGCAAGACCCACAA
CCTGCGCGTGGCCGAATTGATGATGGCCAACGAAAAGGTCTGGCGCAGCGAAGAGGAAATCCGCGCCGGCCTGATGAAGC
TCTGGCGGGCGATGCAGGATTGCGTCGAGCAGGGCCTCAAGCACGAAGGCATCCTGCCCGGCGGTCTCAACGTGCGCCGC
CGCGCGGCGAAGTTGCACCGCAGCCTTCAGGAGTTGAACAAGCCCAACGTGATCGGCTCGACCCTCAGCGCGATGGAGTG
GGTCAACCTGTTCGCCCTCGCGGTGAACGAGGAAAACGCCGCCGGCGGACGCATGGTCACGGCGCCCACCAACGGCGCGG
CGGGGATCATTCCGGCGGTGCTGCACTACTTCATGAAATTCAGCGAGGCGGTGACTGACGCCAACGTGGTCGACTATTTC
CTCGGGGCGGCGGCGGTGGGGATTCTGTGCAAGAAGAACGCTTCGATCTCCGGCGCCGAAGTCGGCTGTCAGGGTGAGGT
CGGTTCGGCCTGTGCGATGGCGGCGGCAGGGTTGGCGGAAATCCTCGGCGCAAGCCCGGAGCAATTGTGCAACGCGGCGG
AAATCGGCCTGGAACACAACCTCGGCCTGACCTGCGATCCGGTGGGTGGTCTGGTGCAAGTGCCGTGCATCGAGCGCAAT
GCGATTGCGGCGGTGAAGGCGATCAACGCGGCGCAGATGGCCTTGCGCGGGGACGGTCAGCACTTTATTTCGCTGGATCG
GGTGATCCGCACCATGCGCGATACCGGCGCCGACATGCATGACAAATATAAAGAGACATCGCGGGGCGGGTTGGCGGTCA
GCGCGGTGGAATGCTGA

Upstream 100 bases:

>100_bases
CCGATGATGCGGGCATTCCGGCGGATCGCAGCTTGAGCGTAGCAGCTCCGCCAGCGGGCGCTTCACGCCCCGGACCGGCA
CTCTCAGGAGCTCTGCAGCA

Downstream 100 bases:

>100_bases
TTCCTCAGATAACGTCGGACCAGTCAAAACTGCGCACCAAGTGAGCATGGGCAATAAAACGCGCCACCTTTTGGCGCGTC
GTTATCAGATAAGAGCCTTT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MAISVFDLFKIGIGPSSSHTVGPMRAAALFVESLRDKHLLEQVRRIEVQLFGSLSATGVGHGSDNAVIMGLMGEWPDAID
PSQIGPRIQALRETHTLLLDGRLSVPFIWGRDMRLIDENLPFHPNAMTLVAEGDRGELHRDTYYSVGGGFVVDEAQASSG
VVDLDRTELPYDFSSAVELLELCKTHNLRVAELMMANEKVWRSEEEIRAGLMKLWRAMQDCVEQGLKHEGILPGGLNVRR
RAAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAVLHYFMKFSEAVTDANVVDYF
LGAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGASPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERN
AIAAVKAINAAQMALRGDGQHFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC

Sequences:

>Translated_458_residues
MAISVFDLFKIGIGPSSSHTVGPMRAAALFVESLRDKHLLEQVRRIEVQLFGSLSATGVGHGSDNAVIMGLMGEWPDAID
PSQIGPRIQALRETHTLLLDGRLSVPFIWGRDMRLIDENLPFHPNAMTLVAEGDRGELHRDTYYSVGGGFVVDEAQASSG
VVDLDRTELPYDFSSAVELLELCKTHNLRVAELMMANEKVWRSEEEIRAGLMKLWRAMQDCVEQGLKHEGILPGGLNVRR
RAAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAVLHYFMKFSEAVTDANVVDYF
LGAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGASPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERN
AIAAVKAINAAQMALRGDGQHFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC
>Mature_457_residues
AISVFDLFKIGIGPSSSHTVGPMRAAALFVESLRDKHLLEQVRRIEVQLFGSLSATGVGHGSDNAVIMGLMGEWPDAIDP
SQIGPRIQALRETHTLLLDGRLSVPFIWGRDMRLIDENLPFHPNAMTLVAEGDRGELHRDTYYSVGGGFVVDEAQASSGV
VDLDRTELPYDFSSAVELLELCKTHNLRVAELMMANEKVWRSEEEIRAGLMKLWRAMQDCVEQGLKHEGILPGGLNVRRR
AAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAVLHYFMKFSEAVTDANVVDYFL
GAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGASPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERNA
IAAVKAINAAQMALRGDGQHFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=457, Percent_Identity=54.4857768052516, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=53.8461538461538, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1789161, Length=457, Percent_Identity=54.2669584245077, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49166; Mature: 49035

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISVFDLFKIGIGPSSSHTVGPMRAAALFVESLRDKHLLEQVRRIEVQLFGSLSATGVG
CEEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
HGSDNAVIMGLMGEWPDAIDPSQIGPRIQALRETHTLLLDGRLSVPFIWGRDMRLIDENL
CCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHEEECCCCCCCEEECCCHHHHCCCC
PFHPNAMTLVAEGDRGELHRDTYYSVGGGFVVDEAQASSGVVDLDRTELPYDFSSAVELL
CCCCCCEEEEEECCCCCCCCCCEEECCCCEEEECCCCCCCCEECCCCCCCCCHHHHHHHH
ELCKTHNLRVAELMMANEKVWRSEEEIRAGLMKLWRAMQDCVEQGLKHEGILPGGLNVRR
HHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RAAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHH
LHYFMKFSEAVTDANVVDYFLGAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ILGASPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERNAIAAVKAINAAQMALRGDGQ
HHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCH
HFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
AISVFDLFKIGIGPSSSHTVGPMRAAALFVESLRDKHLLEQVRRIEVQLFGSLSATGVG
EEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
HGSDNAVIMGLMGEWPDAIDPSQIGPRIQALRETHTLLLDGRLSVPFIWGRDMRLIDENL
CCCCCEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHEEECCCCCCCEEECCCHHHHCCCC
PFHPNAMTLVAEGDRGELHRDTYYSVGGGFVVDEAQASSGVVDLDRTELPYDFSSAVELL
CCCCCCEEEEEECCCCCCCCCCEEECCCCEEEECCCCCCCCEECCCCCCCCCHHHHHHHH
ELCKTHNLRVAELMMANEKVWRSEEEIRAGLMKLWRAMQDCVEQGLKHEGILPGGLNVRR
HHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
RAAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCHHHHHH
LHYFMKFSEAVTDANVVDYFLGAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ILGASPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERNAIAAVKAINAAQMALRGDGQ
HHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCH
HFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]