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The map label for this gene is hlyB [H]

Identifier: 77460979

GI number: 77460979

Start: 5362218

End: 5364275

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_4758

Alternate gene names: 77460979

Gene position: 5362218-5364275 (Clockwise)

Preceding gene: 77460977

Following gene: 77460980

Centisome position: 83.28

GC content: 63.8

Gene sequence:

>2058_bases
ATGCAGGCTTTTTTATCACCGGGGATCAGGTTGCTGGGGCGGTTTGGCTTCGCGCGTAAATTCCAGTTGTTGTTTCTGCT
GTTTATCCTGCCATTGGCCGGCAGCCTGTTAATGATCGGCCAGGACTATCGCGACAAACTCAACCTGATCGCCGGCGAAC
GTGCCGGTGTGCGGCAGTTGCTTGCCCTCGATGCACTCGACAACCTGCTCGCCGCTCAACGTGACCGCGCCGCCCGCTGG
CGCGCCACGGAAACCAACCGCCAGCCGACGCCCGCCACCCTGGCCGCCGTGGCCGCATTCGATGGCGTGCAACCTGCCGT
GGCCCAGGCCACGCTGGAGCTGGGCAATGCCTTGCAAGCCGAAGGCGCGGAAAGCGAAACCCTGACCCGCTATCAGGCTC
TGCAAGCCGCGCTCAATGGTCTGGACTCGAAAAGCCTTTCCGGTGTCGGCTGGTGGCCGGACGGTTACGACCGCTTCACC
AATGCGCTCAGCGCCCTGCAAGCGTTGCGCGAACAAATCGCGATGGACAATCGGCTGATCCTCGCGCCGTGGCTGGAAAC
GTATCTGCTGACACAGATTTCCACCCAGCACGCACCGGACCTGATCGAGCGGGTCGGCCGACTGGCAGCCGTCGGCCAGG
CTTCTGTAGTTTCCGGCCAGTTCACCCTGCAAAGCCGTCTGCAACTGCGTGACCTGCGCAGCCGTATCGGCGACGCCCGC
GAGCAGTTGGTGAAAACCGCGAGCCTGCTCGAAGCGCGTCTGCCGCCAGCCCTGCAAGGCTGGGCCGGGCAGTATCACGA
CAGCCTCAAACAGCTGGATGCCGGGTTGAAAGTGCTGGATGACGGCGTGTTCGGCGGCAGCATCAATCTCAAGCCGGAAG
AGTTCGAACGCAGCCTTGACGCCCTGCTCGGCAACCTTGCCACGTTGCGCCAGCAATCGCTGGTGTCGCTGGATCAGCGG
CTGGATGACTACCATGGATCGGCGATTCGTCAGTTCATCGTTGTCGCGGCGGTCTTCGGTTTTCTGTTGCTGGCGGCGCT
GTACCTGTTCGTCTGCCTGCAAGCCTCGATCCGCCGCAGCGCCAGTGGCATCACGCTGCTGGCCGAGGCCCTGCGTGACG
GCAATCTGAGCCTGCAAGTGCCGGTCGTGGGCCGTGATGAACTGGCGTCGATCAGCACTGCACTCAACGTGGCCGTGGTG
CAGTTGCGCACCAGCCTGCTGGGTGTCGATCACGAGACTTCGCAACTGAGCAACGCCGTGCGCAGCCTTAATGATCACTC
CAGCGGAGCTCTCAGCGAAGTCGAAGCGCAGCAATTGCAGATCAGCCAGATCGCCGCCGCAGCCACGCAATTGGCGGCGA
CCTCCCAGGGCGTGGCGCAGAGTTGCGAACAGGCTTCCGGCAGCGCCCAGCACACCCGGCGCATCGCTGCCGACAGCAGC
CGTGACAGTCAGCGCACCACGGCGAGCATTCAACAGCTCAATCAGCGCCTGAACGAAACTGCCGCAGCGCTCGGCCGGGT
CAGCGAGCAAGGGCAGCAGATTCAATTGGTGGTCGACACCATCCGTGGCGTCGCCGAGCAGACCAACTTGCTCGCACTCA
ACGCCGCTATCGAGGCCGCTCGCGCGGGTGAACAAGGTCGTGGTTTTGCCGTGGTGGCGGATGAGGTGCGCAGCCTGTCG
CAACGTACGCAGTCGTCCACGGCGCAGATTGCCGGAACGGTCGACAGCCTGCGCAATACGGTCAATGAAGCCGTGAGCCT
GATGGAGGCTGCGTGCGGCCAGGCGCAATCGGACGCGGAAGCCGTCACGGGACTTGGCGAACGCCTGGGGGAAATCGCCA
GCGCCGTGCAGAGCGTCACTGACACCCTCGCCCAGATCGCCACGGCAGTCGAAGAACAGGCGAGCACCGCCGATGAGGTC
AGCGGCAATATCCAGCAGGTGGATCAGGCGGCAGTTCGCCTGCTCGAAGGCGCGCGGGCGGTGAACCTTGCGGCGGACAC
CTTGAGCCAGGGCAGCCATGCCTTGAGTGCCAACACCGGAAGATTTCAGCTGCGTTGA

Upstream 100 bases:

>100_bases
CAAGGGTGAACTTTCGAGGCCTTTTAGCAGGGCACCAATCCCGGTCGCAGCGACCGGGATGCACGCCGATGGTGCGTGGT
GTCCAGAGGAGTCATGGGGC

Downstream 100 bases:

>100_bases
AAGCCCTTCCCGCGCCTTTTTTCGGCGCGGGAGGATAAGCGGTTGAAAATAAGAAGAAATATTTTGAATTTACGCTTGAC
GCTTTTCCATTTCAGGGGAA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MQAFLSPGIRLLGRFGFARKFQLLFLLFILPLAGSLLMIGQDYRDKLNLIAGERAGVRQLLALDALDNLLAAQRDRAARW
RATETNRQPTPATLAAVAAFDGVQPAVAQATLELGNALQAEGAESETLTRYQALQAALNGLDSKSLSGVGWWPDGYDRFT
NALSALQALREQIAMDNRLILAPWLETYLLTQISTQHAPDLIERVGRLAAVGQASVVSGQFTLQSRLQLRDLRSRIGDAR
EQLVKTASLLEARLPPALQGWAGQYHDSLKQLDAGLKVLDDGVFGGSINLKPEEFERSLDALLGNLATLRQQSLVSLDQR
LDDYHGSAIRQFIVVAAVFGFLLLAALYLFVCLQASIRRSASGITLLAEALRDGNLSLQVPVVGRDELASISTALNVAVV
QLRTSLLGVDHETSQLSNAVRSLNDHSSGALSEVEAQQLQISQIAAAATQLAATSQGVAQSCEQASGSAQHTRRIAADSS
RDSQRTTASIQQLNQRLNETAAALGRVSEQGQQIQLVVDTIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLS
QRTQSSTAQIAGTVDSLRNTVNEAVSLMEAACGQAQSDAEAVTGLGERLGEIASAVQSVTDTLAQIATAVEEQASTADEV
SGNIQQVDQAAVRLLEGARAVNLAADTLSQGSHALSANTGRFQLR

Sequences:

>Translated_685_residues
MQAFLSPGIRLLGRFGFARKFQLLFLLFILPLAGSLLMIGQDYRDKLNLIAGERAGVRQLLALDALDNLLAAQRDRAARW
RATETNRQPTPATLAAVAAFDGVQPAVAQATLELGNALQAEGAESETLTRYQALQAALNGLDSKSLSGVGWWPDGYDRFT
NALSALQALREQIAMDNRLILAPWLETYLLTQISTQHAPDLIERVGRLAAVGQASVVSGQFTLQSRLQLRDLRSRIGDAR
EQLVKTASLLEARLPPALQGWAGQYHDSLKQLDAGLKVLDDGVFGGSINLKPEEFERSLDALLGNLATLRQQSLVSLDQR
LDDYHGSAIRQFIVVAAVFGFLLLAALYLFVCLQASIRRSASGITLLAEALRDGNLSLQVPVVGRDELASISTALNVAVV
QLRTSLLGVDHETSQLSNAVRSLNDHSSGALSEVEAQQLQISQIAAAATQLAATSQGVAQSCEQASGSAQHTRRIAADSS
RDSQRTTASIQQLNQRLNETAAALGRVSEQGQQIQLVVDTIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLS
QRTQSSTAQIAGTVDSLRNTVNEAVSLMEAACGQAQSDAEAVTGLGERLGEIASAVQSVTDTLAQIATAVEEQASTADEV
SGNIQQVDQAAVRLLEGARAVNLAADTLSQGSHALSANTGRFQLR
>Mature_685_residues
MQAFLSPGIRLLGRFGFARKFQLLFLLFILPLAGSLLMIGQDYRDKLNLIAGERAGVRQLLALDALDNLLAAQRDRAARW
RATETNRQPTPATLAAVAAFDGVQPAVAQATLELGNALQAEGAESETLTRYQALQAALNGLDSKSLSGVGWWPDGYDRFT
NALSALQALREQIAMDNRLILAPWLETYLLTQISTQHAPDLIERVGRLAAVGQASVVSGQFTLQSRLQLRDLRSRIGDAR
EQLVKTASLLEARLPPALQGWAGQYHDSLKQLDAGLKVLDDGVFGGSINLKPEEFERSLDALLGNLATLRQQSLVSLDQR
LDDYHGSAIRQFIVVAAVFGFLLLAALYLFVCLQASIRRSASGITLLAEALRDGNLSLQVPVVGRDELASISTALNVAVV
QLRTSLLGVDHETSQLSNAVRSLNDHSSGALSEVEAQQLQISQIAAAATQLAATSQGVAQSCEQASGSAQHTRRIAADSS
RDSQRTTASIQQLNQRLNETAAALGRVSEQGQQIQLVVDTIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLS
QRTQSSTAQIAGTVDSLRNTVNEAVSLMEAACGQAQSDAEAVTGLGERLGEIASAVQSVTDTLAQIATAVEEQASTADEV
SGNIQQVDQAAVRLLEGARAVNLAADTLSQGSHALSANTGRFQLR

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=324, Percent_Identity=29.0123456790123, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI2367378, Length=335, Percent_Identity=28.6567164179104, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=423, Percent_Identity=28.6052009456265, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788195, Length=276, Percent_Identity=29.7101449275362, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789453, Length=312, Percent_Identity=26.9230769230769, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72985; Mature: 72985

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFLSPGIRLLGRFGFARKFQLLFLLFILPLAGSLLMIGQDYRDKLNLIAGERAGVRQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCHHHHHHH
LALDALDNLLAAQRDRAARWRATETNRQPTPATLAAVAAFDGVQPAVAQATLELGNALQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHC
EGAESETLTRYQALQAALNGLDSKSLSGVGWWPDGYDRFTNALSALQALREQIAMDNRLI
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
LAPWLETYLLTQISTQHAPDLIERVGRLAAVGQASVVSGQFTLQSRLQLRDLRSRIGDAR
EHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
EQLVKTASLLEARLPPALQGWAGQYHDSLKQLDAGLKVLDDGVFGGSINLKPEEFERSLD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ALLGNLATLRQQSLVSLDQRLDDYHGSAIRQFIVVAAVFGFLLLAALYLFVCLQASIRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ASGITLLAEALRDGNLSLQVPVVGRDELASISTALNVAVVQLRTSLLGVDHETSQLSNAV
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RSLNDHSSGALSEVEAQQLQISQIAAAATQLAATSQGVAQSCEQASGSAQHTRRIAADSS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
RDSQRTTASIQQLNQRLNETAAALGRVSEQGQQIQLVVDTIRGVAEQTNLLALNAAIEAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RAGEQGRGFAVVADEVRSLSQRTQSSTAQIAGTVDSLRNTVNEAVSLMEAACGQAQSDAE
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AVTGLGERLGEIASAVQSVTDTLAQIATAVEEQASTADEVSGNIQQVDQAAVRLLEGARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCHH
VNLAADTLSQGSHALSANTGRFQLR
HHHHHHHHHCCCCEEECCCCCEECC
>Mature Secondary Structure
MQAFLSPGIRLLGRFGFARKFQLLFLLFILPLAGSLLMIGQDYRDKLNLIAGERAGVRQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCHHHHHHH
LALDALDNLLAAQRDRAARWRATETNRQPTPATLAAVAAFDGVQPAVAQATLELGNALQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHC
EGAESETLTRYQALQAALNGLDSKSLSGVGWWPDGYDRFTNALSALQALREQIAMDNRLI
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
LAPWLETYLLTQISTQHAPDLIERVGRLAAVGQASVVSGQFTLQSRLQLRDLRSRIGDAR
EHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
EQLVKTASLLEARLPPALQGWAGQYHDSLKQLDAGLKVLDDGVFGGSINLKPEEFERSLD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ALLGNLATLRQQSLVSLDQRLDDYHGSAIRQFIVVAAVFGFLLLAALYLFVCLQASIRRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ASGITLLAEALRDGNLSLQVPVVGRDELASISTALNVAVVQLRTSLLGVDHETSQLSNAV
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RSLNDHSSGALSEVEAQQLQISQIAAAATQLAATSQGVAQSCEQASGSAQHTRRIAADSS
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
RDSQRTTASIQQLNQRLNETAAALGRVSEQGQQIQLVVDTIRGVAEQTNLLALNAAIEAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RAGEQGRGFAVVADEVRSLSQRTQSSTAQIAGTVDSLRNTVNEAVSLMEAACGQAQSDAE
HCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AVTGLGERLGEIASAVQSVTDTLAQIATAVEEQASTADEVSGNIQQVDQAAVRLLEGARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCHH
VNLAADTLSQGSHALSANTGRFQLR
HHHHHHHHHCCCCEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]