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The map label for this gene is engD [H]

Identifier: 77460977

GI number: 77460977

Start: 5359504

End: 5360604

Strand: Direct

Name: engD [H]

Synonym: Pfl01_4756

Alternate gene names: 77460977

Gene position: 5359504-5360604 (Clockwise)

Preceding gene: 77460976

Following gene: 77460979

Centisome position: 83.24

GC content: 60.76

Gene sequence:

>1101_bases
ATGGGATTCAATTGCGGCATCGTCGGCCTGCCTAACGTCGGCAAGTCCACCCTGTTCAACGCCCTGACCAAGTCCGGGAT
CGCGGCCGAGAACTTCCCCTTCTGCACCATCGAGCCGAACAGCGGCATCGTGCCGATGCCGGATCCGCGTCTCGACGCTC
TGGCGGCCATCGTCAATCCGAAGCGCATCCTGCCGACCACCATGGAATTCGTCGACATCGCGGGCCTGGTTGCCGGCGCG
TCGAAAGGTGAAGGCCTGGGCAACAAGTTCCTGGCCAACATCCGCGAAACCGACGCGATCGCTCACGTCGTGCGCTGCTT
CGAAGACGAGAACGTGATCCACGTCTCCAACAGCGTCGACCCGAAACGCGACATCGAAATCATCGACCTGGAACTGATCT
TCGCCGACCTCGACAGCTGCGAGAAGCAACTGCAGAAAGTCGCGCGCAACGCCAAGGGCGGTGACAAGGACGCGGTGGCC
CAGAAGGCCCTGCTTGAGCAGTTGATCCCGCACTTCAGCGAAGGCAAGCCTGCGCGCAGCCTGATGAAGAACATGAGCGC
CGACGAAAAGGCCATCATCAAGGGCTTCCACCTGCTGACCACCAAACCGGTCATGTACATCGCCAACGTCGCTGAAGACG
GTTTCGAGAACAACCCGCACCTGGACGTGGTCAAGGCCATCGCCGAAGAAGAAGGCGCGATGGTTGTCCCGGTCTGCAAC
AAGATCGAAGCGGAAATCGCCGAGCTGGACGACGGCGAAGAGAAAGACATGTTCCTCGAGGCCCTGGGCCTGGAAGAGCC
TGGCCTGAACCGCGTGATCCGCGCCGGCTACGAAATGCTGCACCTGCAGACCTACTTCACTGCCGGTGTCGAAGAAGTCC
GCGCCTGGACCGTCCGCGTCGGTGCCACCGCACCGCAAGCAGCCGGCGTGATCCACACCGACTTCGAGAAAGGCTTCATC
CGCGCCGAAGTGATCGCCTACAACGACTTCATCCAGTACAAGGGTGAAGCAGGCACCAAGGAAGCCGGCAAATGGCGCCT
GGAAGGCAAGGATTACATCGTCAAGGACGGCGACGTGATGCACTTCCGCTTCAACGTGTAA

Upstream 100 bases:

>100_bases
GCCCTCGGCGTGCTGCCGGATATCCTCGCCGGTGAATGGAACCGCGCGATGAAAAACCTGCACAGCCAGAAGGCCTGACT
CTAATCCGAGGGGAAACACC

Downstream 100 bases:

>100_bases
AAGCTGCACCCAAGAAAAAGCCGCGTTGATACGCGGCTTTTTTTTGCCCGAAATTCAGCCTGTCAGGCTTTTTTGGTTCT
CGGCAGGAAGATCGTCAGCA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLDALAAIVNPKRILPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVARNAKGGDKDAVA
QKALLEQLIPHFSEGKPARSLMKNMSADEKAIIKGFHLLTTKPVMYIANVAEDGFENNPHLDVVKAIAEEEGAMVVPVCN
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFI
RAEVIAYNDFIQYKGEAGTKEAGKWRLEGKDYIVKDGDVMHFRFNV

Sequences:

>Translated_366_residues
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLDALAAIVNPKRILPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVARNAKGGDKDAVA
QKALLEQLIPHFSEGKPARSLMKNMSADEKAIIKGFHLLTTKPVMYIANVAEDGFENNPHLDVVKAIAEEEGAMVVPVCN
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFI
RAEVIAYNDFIQYKGEAGTKEAGKWRLEGKDYIVKDGDVMHFRFNV
>Mature_365_residues
GFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLDALAAIVNPKRILPTTMEFVDIAGLVAGAS
KGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVDPKRDIEIIDLELIFADLDSCEKQLQKVARNAKGGDKDAVAQ
KALLEQLIPHFSEGKPARSLMKNMSADEKAIIKGFHLLTTKPVMYIANVAEDGFENNPHLDVVKAIAEEEGAMVVPVCNK
IEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRVGATAPQAAGVIHTDFEKGFIR
AEVIAYNDFIQYKGEAGTKEAGKWRLEGKDYIVKDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.5652173913043, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI58761502, Length=228, Percent_Identity=38.5964912280702, Blast_Score=158, Evalue=7e-39,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=71.3114754098361, Blast_Score=541, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=42.3913043478261, Blast_Score=285, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=39.572192513369, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=34.4736842105263, Blast_Score=204, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=43.4426229508197, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=43.4426229508197, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=43.4426229508197, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.2439024390244, Blast_Score=230, Evalue=1e-60,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40029; Mature: 39898

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLDALAAIVNP
CCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
KRILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVD
CHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PKRDIEIIDLELIFADLDSCEKQLQKVARNAKGGDKDAVAQKALLEQLIPHFSEGKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LMKNMSADEKAIIKGFHLLTTKPVMYIANVAEDGFENNPHLDVVKAIAEEEGAMVVPVCN
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECC
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRV
CHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEE
GATAPQAAGVIHTDFEKGFIRAEVIAYNDFIQYKGEAGTKEAGKWRLEGKDYIVKDGDVM
CCCCCCCCCCEEECCCCCCEEEEEEEEEHHHEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
GFNCGIVGLPNVGKSTLFNALTKSGIAAENFPFCTIEPNSGIVPMPDPRLDALAAIVNP
CCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
KRILPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIAHVVRCFEDENVIHVSNSVD
CHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PKRDIEIIDLELIFADLDSCEKQLQKVARNAKGGDKDAVAQKALLEQLIPHFSEGKPARS
CCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LMKNMSADEKAIIKGFHLLTTKPVMYIANVAEDGFENNPHLDVVKAIAEEEGAMVVPVCN
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECC
KIEAEIAELDDGEEKDMFLEALGLEEPGLNRVIRAGYEMLHLQTYFTAGVEEVRAWTVRV
CHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEE
GATAPQAAGVIHTDFEKGFIRAEVIAYNDFIQYKGEAGTKEAGKWRLEGKDYIVKDGDVM
CCCCCCCCCCEEECCCCCCEEEEEEEEEHHHEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA