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The map label for this gene is mraY [H]

Identifier: 77460897

GI number: 77460897

Start: 5278784

End: 5279866

Strand: Reverse

Name: mraY [H]

Synonym: Pfl01_4676

Alternate gene names: 77460897

Gene position: 5279866-5278784 (Counterclockwise)

Preceding gene: 77460898

Following gene: 77460896

Centisome position: 82.01

GC content: 61.03

Gene sequence:

>1083_bases
ATGCTGCTGCTGCTAGCGGAGTATCTGCAACAGTTCTACAAAGGCTTCGCGGTCTTCCAGTACCTGACCCTGCGCGGGAT
CCTCGGTGTGCTGACCGCGCTGGTCCTGTCGCTGTGCTACGGCCCGTGGATGATCCGCACCCTGCAGAACCGTCAGATCG
GTCAGTCGGTTCGTAACGACGGCCCGCAATCGCACTTGTCCAAGTCCGGTACGCCGACCATGGGCGGTGCGCTGATTCTG
TCTTCGATCGGCGTCAGCACTCTGCTGTGGGCTGACCTGAGCAACCGCTACGTGTGGGTCGTGCTGCTGGTGACCCTGCT
GTTCGGCGCCATCGGCTGGGTCGACGACTACCGCAAGGTGATCGAGAAGAACTCCCGTGGTCTGCCGAGCCGCTGGAAAT
ATTTCTGGCAGTCGGTGTTCGGCCTCGGCGCGGCGATCTTCCTTTATATGACGGCCAGCACTCCGGTGGAAACCACCCTG
ATCCTGCCGATGCTCAAGGACTACAGCATTCCGCTGGGCGCAGGCTTCATCGTGCTGACGTACTTTGTGATCGTCGGTTC
GAGCAACGCGGTCAACCTCACCGACGGCCTCGACGGTCTGGCGATCATGCCGACGGTGATGGTCGGCGGTGGTCTGGGCA
TCTTCTGCTACCTGTCGGGTAACGTGAAATTCGCTGAATACCTGCTGATCCCTTACGTACCGGGCGCAGGCGAGCTGATC
GTGTTCTGCGGCGCATTGATCGGTGCCGGCCTGGGCTTCCTGTGGTTCAACACCTACCCGGCGCAAGTCTTCATGGGTGA
CGTCGGCGCACTGGCGCTGGGCGCGGCCCTGGGCACCATCGCGGTGATCGTCCGTCAGGAAATCGTCCTGTTCATCATGG
GCGGCGTGTTCGTGATGGAAACCCTGTCAGTCGTCATTCAGGTTGCGTCCTTTAAGCTGACCGGTCGCCGTGTGTTCCGC
ATGGCACCGATTCACCACCACTTTGAACTCAAGGGCTGGCCCGAGCCGCGCGTGATCGTCCGTTTCTGGATCATCACCGT
GATTCTCGTGCTGATCGGCCTTGCCACCCTGAAGCTGAGGTAG

Upstream 100 bases:

>100_bases
AGCAGGACACAAACACCACCATTTTGATCAAGGGTTCGCGCAGCGCAGCGATGGAAAACATCGTTGCGGCCCTGTGCGGG
TCCAGTCTGGAGAAACATTA

Downstream 100 bases:

>100_bases
AACGAGTGTCTCTGATCGCTTCTGACCACTTCCGCATCGTTGTCGGCCTCGGCAAGAGCGGCATGTCCCTGGTTCGCTTC
CTGGCGAACCGGGGCGTGGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALVLSLCYGPWMIRTLQNRQIGQSVRNDGPQSHLSKSGTPTMGGALIL
SSIGVSTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTASTPVETTL
ILPMLKDYSIPLGAGFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGGLGIFCYLSGNVKFAEYLLIPYVPGAGELI
VFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFR
MAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR

Sequences:

>Translated_360_residues
MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALVLSLCYGPWMIRTLQNRQIGQSVRNDGPQSHLSKSGTPTMGGALIL
SSIGVSTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTASTPVETTL
ILPMLKDYSIPLGAGFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGGLGIFCYLSGNVKFAEYLLIPYVPGAGELI
VFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFR
MAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
>Mature_360_residues
MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALVLSLCYGPWMIRTLQNRQIGQSVRNDGPQSHLSKSGTPTMGGALIL
SSIGVSTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTASTPVETTL
ILPMLKDYSIPLGAGFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGGLGIFCYLSGNVKFAEYLLIPYVPGAGELI
VFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFR
MAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=64.7222222222222, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39443; Mature: 39443

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALVLSLCYGPWMIRTLQNRQIGQSVRND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPQSHLSKSGTPTMGGALILSSIGVSTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKV
CCHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTASTPVETTLILPMLKDYSIPLGAGFIVLT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCCHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPTVMVGGGLGIFCYLSGNVKFAEYLLIPYVPGAGELI
HHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEEEEECCCCCCHHH
VFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVVIQVASFKLTGRRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
HHHHHHHHHHHHCCCCHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALVLSLCYGPWMIRTLQNRQIGQSVRND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GPQSHLSKSGTPTMGGALILSSIGVSTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKV
CCHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTASTPVETTLILPMLKDYSIPLGAGFIVLT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCCHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPTVMVGGGLGIFCYLSGNVKFAEYLLIPYVPGAGELI
HHHHHCCCCCEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEEEEEECCCCCCHHH
VFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVVIQVASFKLTGRRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
HHHHHHHHHHHHCCCCHHEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA