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The map label for this gene is grxD [H]

Identifier: 77460745

GI number: 77460745

Start: 5097624

End: 5097965

Strand: Reverse

Name: grxD [H]

Synonym: Pfl01_4524

Alternate gene names: 77460745

Gene position: 5097965-5097624 (Counterclockwise)

Preceding gene: 77460746

Following gene: 77460742

Centisome position: 79.18

GC content: 58.19

Gene sequence:

>342_bases
ATGGATATCATCGAAACGATTAAAGAGCAGATTGCCAACAACACCATTCTGCTTTACATGAAAGGCTCGCCGAATGCCCC
CCAGTGTGGCTTCTCCGCGAAAGCTGCGCAGGCTGTGATGGGCTGCGGCGAGAAGTTCGCCTACGTCGACATCCTGCAGA
ACCCGGAAATCCGCGCCAACCTGCCGAAGTACGCCAACTGGCCGACTTTCCCGCAGCTGTGGGTAGCCGGTGAACTGGTC
GGCGGCAGCGACATCATGGCTGAAATGTTTGCCAACGGTGAGCTGCAGACCCTGGTCAAGGAAGCATCCGCCAAGGCTGC
TGCGGCCAAGTCCCAAGCCTGA

Upstream 100 bases:

>100_bases
TGAGCAAGTCTGTCGGGGAGACCGAGCAGGGCGCTCGGGATTCCGTTACAATGCGCCACCGTGCCGACCCATGAGTCGGA
AAGTTCAGCCGAGGTGCTCC

Downstream 100 bases:

>100_bases
TTGGCTTCTGCCCGGATTTCGGCGAGCTGAAGTCCGGGCAATAAAAAGCCCCGCCTCTCGAAAGAGGGCGGGGCTTTTTA
GTGTCGCGAGTTTAGCGCTG

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIMAEMFANGELQTLVKEASAKAAAAKSQA

Sequences:

>Translated_113_residues
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIMAEMFANGELQTLVKEASAKAAAAKSQA
>Mature_113_residues
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRANLPKYANWPTFPQLWVAGELV
GGSDIMAEMFANGELQTLVKEASAKAAAAKSQA

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=86, Percent_Identity=43.0232558139535, Blast_Score=89, Evalue=5e-19,
Organism=Homo sapiens, GI42516576, Length=104, Percent_Identity=35.5769230769231, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787943, Length=110, Percent_Identity=69.0909090909091, Blast_Score=165, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI71988153, Length=85, Percent_Identity=37.6470588235294, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=85, Percent_Identity=37.6470588235294, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556042, Length=91, Percent_Identity=32.967032967033, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=107, Percent_Identity=38.3177570093458, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=73, Percent_Identity=45.2054794520548, Blast_Score=85, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321022, Length=73, Percent_Identity=43.8356164383562, Blast_Score=84, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24642023, Length=112, Percent_Identity=37.5, Blast_Score=92, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19921242, Length=96, Percent_Identity=40.625, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12122; Mature: 12122

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRAN
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCC
LPKYANWPTFPQLWVAGELVGGSDIMAEMFANGELQTLVKEASAKAAAAKSQA
CCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIIETIKEQIANNTILLYMKGSPNAPQCGFSAKAAQAVMGCGEKFAYVDILQNPEIRAN
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCC
LPKYANWPTFPQLWVAGELVGGSDIMAEMFANGELQTLVKEASAKAAAAKSQA
CCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]