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The map label for this gene is fdhA [H]

Identifier: 77460746

GI number: 77460746

Start: 5098063

End: 5100168

Strand: Reverse

Name: fdhA [H]

Synonym: Pfl01_4525

Alternate gene names: 77460746

Gene position: 5100168-5098063 (Counterclockwise)

Preceding gene: 77460747

Following gene: 77460745

Centisome position: 79.21

GC content: 62.2

Gene sequence:

>2106_bases
ATGACCAAGACTCTCCACCACCGTGCCTGCCACCTGTGTGAAGCCATCTGCGGCTTGACCATCGAAACCACCGAAACCGA
CGGCCAGGTGCAGATCACCTCGATCAAGGGCGATGCCCTGGACACGTTCAGTCGTGGGCACATCTGCCCCAAGGCCGTCG
CGCTGCAAGATATCCAGAACGATCCGGATCGCCTGCGTCAGCCGATGCGCCGGGTCGGCAGCGAATGGCTGCCCATCGAG
TGGGACGAGGCGGTCGAGCTGGTCGCCGAAAAACTCTCGGCGATTCAGGAGCGTCATGGGCAGAACGCGGTCGCCGTGTA
TCAGGGCAACCCCAGCGTGCACAACTACGGGTTGATGACCCACAGCAATTACTTCCTCGGCCTGTTGAAAACCCGCAACC
GCTATTCGGCGACGTCGGTCGATCAACTGCCCCATCACCTGACCAGCTACCTGATGTACGGCCACGGCCTGCTGCTGCCG
ATCCCGGACATCGATCACACCGATTTCATGCTGATCCTGGGCGGTAATCCACTGGCCTCCAACGGCAGCATCATGACTGT
GCCGGATGTCGAGAAGCGTCTGAAAGCGATCCAGGCCCGAGGCGGCAAAGTGGTGGTGGTCGATCCACGGCGCAGCGAGA
CGGCGGCGATGGCCGATCAGCATCTGTTCGTGCGCCCCGGCGGCGATGCGGCGTTGTTGTTTGGTGTGCTTAATACGTTG
TTCAGCGAAGGACTGACGTCTGACAGTCATTTGCCGGTGGACGGTCTGGACGACGTGCGCGCGGCGGTGGCGGGGTTCAC
CGCTGAAGCCATGAGCCCGTTGTGCGCCGTTCCCTCCGAACAGATCCGCCAGTTGGCCCGGGACTTCGCCGCTGCGCCAA
GCGCCGTTTGCTACGGTCGGATGGGGGTTTCCACTCAAGCCTTCGGCACGCTGTGTCATTGGGTTGTGCAGCTGATCAAT
CTGGTCACCGGCAACCTGGACCGCGTCGGTGGTGCCTTGTGCACCGAGCCGGCGGTGGATCTGGTCGCCTCGACTTCAGG
CGGGCACTTCAATAAATGGCAGAGCCGCGTGTCCGGACGTCCCGAGTACGGCGGTGAGCTGCCGGTCTCGGCGCTGGCTG
AAGAAATGCTCACAGAGGGTGAAGGGCAGATTCGCGCGCTGATCACCGTGGCCGGCAATCCAGTGTTGTCCACGCCCAAT
GGCCGACAACTGGAGCAGGCGCTGGACGGGCTGGAATTCATGGTCAGTGTCGACCTGTATATCAACGAAACCACGCGCTA
CGCCGATCTGATCCTGCCATCGACTTCGGCGCTGGAGAACGATCACTACGACACCACTTTCAATCTGTTTGCGGTGCGCA
ACGTCACTCGATTCAACCGGGCAATCCTCGCCAAACCCGAAGGGGCGCTGCACGACTGGGAAATCTTCGTCGGCCTGGCC
AAGGCCTTCGCCGCGAAGACCGGCAAGGAGCTGAAACCGACGATGCCGCCGTCGAAGATGATCGACACGGGATTGCGCAT
GGGCGCCTATGGCGATGCGTCCGAGCATAAATTGTCGCTGGCGACGCTGTTCGATCATCCGCACGGTGTTGACCTGGGAG
CGCTGAAACCCAACCTGACACCGCGATTGAAGACCTTCAATCAACGAGTTCAGGCGGCGCCGCCGGAAATCCTCGCCGAT
CTGGCGCGCTTCGCCGCGTTGCAGGCGCCGGCCGCCGATGAGCTGTTGATGATTGGTCGCCGTCATGTACGCAGCAACAA
TTCGTGGATGCACAATTACCACCGGTTGGTGAAGGGCAAGCCGCGTCATCAGTTGTTGATGAATCCGGACGATCTCGCCA
GTCGCGGGCTCAGTGATGGTCAGCTTGTCCGGGTCAGTTCGCGGGTCGGGCAGATCGAGGTCGAGGTGCTGGGCAGTGCG
GACATGATGAAGGGCGTGGTCAGCCTGCCGCATGGATGGGGCCATGCCCGGCCGGGCGTGCAGATGGCGATTGCCAGCGG
TCAGCCGGGCTCCAGTGCCAATGACCTGACCGATGAATGCCAGCTCGACGAGCTGTCAGGCAATGCGGCGCTCAATGGCG
TGCCGGTGACCGTGGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GATTCACAAGACGAACGTCGCTGGCGCTGCACCGGGTCGCGGGCCATAGTTTTGTTCCCGCAGGCGTGATTGCCTGCCCA
GAACAAGACAGAGACTGGCC

Downstream 100 bases:

>100_bases
GCAAGTCTGTCGGGGAGACCGAGCAGGGCGCTCGGGATTCCGTTACAATGCGCCACCGTGCCGACCCATGAGTCGGAAAG
TTCAGCCGAGGTGCTCCATG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MTKTLHHRACHLCEAICGLTIETTETDGQVQITSIKGDALDTFSRGHICPKAVALQDIQNDPDRLRQPMRRVGSEWLPIE
WDEAVELVAEKLSAIQERHGQNAVAVYQGNPSVHNYGLMTHSNYFLGLLKTRNRYSATSVDQLPHHLTSYLMYGHGLLLP
IPDIDHTDFMLILGGNPLASNGSIMTVPDVEKRLKAIQARGGKVVVVDPRRSETAAMADQHLFVRPGGDAALLFGVLNTL
FSEGLTSDSHLPVDGLDDVRAAVAGFTAEAMSPLCAVPSEQIRQLARDFAAAPSAVCYGRMGVSTQAFGTLCHWVVQLIN
LVTGNLDRVGGALCTEPAVDLVASTSGGHFNKWQSRVSGRPEYGGELPVSALAEEMLTEGEGQIRALITVAGNPVLSTPN
GRQLEQALDGLEFMVSVDLYINETTRYADLILPSTSALENDHYDTTFNLFAVRNVTRFNRAILAKPEGALHDWEIFVGLA
KAFAAKTGKELKPTMPPSKMIDTGLRMGAYGDASEHKLSLATLFDHPHGVDLGALKPNLTPRLKTFNQRVQAAPPEILAD
LARFAALQAPAADELLMIGRRHVRSNNSWMHNYHRLVKGKPRHQLLMNPDDLASRGLSDGQLVRVSSRVGQIEVEVLGSA
DMMKGVVSLPHGWGHARPGVQMAIASGQPGSSANDLTDECQLDELSGNAALNGVPVTVAAA

Sequences:

>Translated_701_residues
MTKTLHHRACHLCEAICGLTIETTETDGQVQITSIKGDALDTFSRGHICPKAVALQDIQNDPDRLRQPMRRVGSEWLPIE
WDEAVELVAEKLSAIQERHGQNAVAVYQGNPSVHNYGLMTHSNYFLGLLKTRNRYSATSVDQLPHHLTSYLMYGHGLLLP
IPDIDHTDFMLILGGNPLASNGSIMTVPDVEKRLKAIQARGGKVVVVDPRRSETAAMADQHLFVRPGGDAALLFGVLNTL
FSEGLTSDSHLPVDGLDDVRAAVAGFTAEAMSPLCAVPSEQIRQLARDFAAAPSAVCYGRMGVSTQAFGTLCHWVVQLIN
LVTGNLDRVGGALCTEPAVDLVASTSGGHFNKWQSRVSGRPEYGGELPVSALAEEMLTEGEGQIRALITVAGNPVLSTPN
GRQLEQALDGLEFMVSVDLYINETTRYADLILPSTSALENDHYDTTFNLFAVRNVTRFNRAILAKPEGALHDWEIFVGLA
KAFAAKTGKELKPTMPPSKMIDTGLRMGAYGDASEHKLSLATLFDHPHGVDLGALKPNLTPRLKTFNQRVQAAPPEILAD
LARFAALQAPAADELLMIGRRHVRSNNSWMHNYHRLVKGKPRHQLLMNPDDLASRGLSDGQLVRVSSRVGQIEVEVLGSA
DMMKGVVSLPHGWGHARPGVQMAIASGQPGSSANDLTDECQLDELSGNAALNGVPVTVAAA
>Mature_700_residues
TKTLHHRACHLCEAICGLTIETTETDGQVQITSIKGDALDTFSRGHICPKAVALQDIQNDPDRLRQPMRRVGSEWLPIEW
DEAVELVAEKLSAIQERHGQNAVAVYQGNPSVHNYGLMTHSNYFLGLLKTRNRYSATSVDQLPHHLTSYLMYGHGLLLPI
PDIDHTDFMLILGGNPLASNGSIMTVPDVEKRLKAIQARGGKVVVVDPRRSETAAMADQHLFVRPGGDAALLFGVLNTLF
SEGLTSDSHLPVDGLDDVRAAVAGFTAEAMSPLCAVPSEQIRQLARDFAAAPSAVCYGRMGVSTQAFGTLCHWVVQLINL
VTGNLDRVGGALCTEPAVDLVASTSGGHFNKWQSRVSGRPEYGGELPVSALAEEMLTEGEGQIRALITVAGNPVLSTPNG
RQLEQALDGLEFMVSVDLYINETTRYADLILPSTSALENDHYDTTFNLFAVRNVTRFNRAILAKPEGALHDWEIFVGLAK
AFAAKTGKELKPTMPPSKMIDTGLRMGAYGDASEHKLSLATLFDHPHGVDLGALKPNLTPRLKTFNQRVQAAPPEILADL
ARFAALQAPAADELLMIGRRHVRSNNSWMHNYHRLVKGKPRHQLLMNPDDLASRGLSDGQLVRVSSRVGQIEVEVLGSAD
MMKGVVSLPHGWGHARPGVQMAIASGQPGSSANDLTDECQLDELSGNAALNGVPVTVAAA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=688, Percent_Identity=24.8546511627907, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1787870, Length=736, Percent_Identity=23.3695652173913, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI171474008, Length=731, Percent_Identity=22.1614227086183, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693196, Length=775, Percent_Identity=21.9354838709677, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081994, Length=717, Percent_Identity=20.9205020920502, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI3868720, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI3868719, Length=250, Percent_Identity=26, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787778, Length=479, Percent_Identity=24.8434237995825, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 75770; Mature: 75639

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTLHHRACHLCEAICGLTIETTETDGQVQITSIKGDALDTFSRGHICPKAVALQDIQN
CCCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCHHHHCCCCCCCHHHHHHHHHCC
DPDRLRQPMRRVGSEWLPIEWDEAVELVAEKLSAIQERHGQNAVAVYQGNPSVHNYGLMT
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
HSNYFLGLLKTRNRYSATSVDQLPHHLTSYLMYGHGLLLPIPDIDHTDFMLILGGNPLAS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCC
NGSIMTVPDVEKRLKAIQARGGKVVVVDPRRSETAAMADQHLFVRPGGDAALLFGVLNTL
CCCEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHH
FSEGLTSDSHLPVDGLDDVRAAVAGFTAEAMSPLCAVPSEQIRQLARDFAAAPSAVCYGR
HHCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCHHCCCHHHHHHHHHHHHCCCCHHEECC
MGVSTQAFGTLCHWVVQLINLVTGNLDRVGGALCTEPAVDLVASTSGGHFNKWQSRVSGR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCHHHHHEECCCCCCHHHHHHHHCCC
PEYGGELPVSALAEEMLTEGEGQIRALITVAGNPVLSTPNGRQLEQALDGLEFMVSVDLY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCHHHHHHHCCCEEEEEEEEE
INETTRYADLILPSTSALENDHYDTTFNLFAVRNVTRFNRAILAKPEGALHDWEIFVGLA
ECCCCCEEHEECCCCHHHCCCCCCCEEEEEEEHHHHHHCCEEEECCCCCCCHHHHHHHHH
KAFAAKTGKELKPTMPPSKMIDTGLRMGAYGDASEHKLSLATLFDHPHGVDLGALKPNLT
HHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
PRLKTFNQRVQAAPPEILADLARFAALQAPAADELLMIGRRHVRSNNSWMHNYHRLVKGK
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PRHQLLMNPDDLASRGLSDGQLVRVSSRVGQIEVEVLGSADMMKGVVSLPHGWGHARPGV
CCCEECCCCHHHHHCCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCC
QMAIASGQPGSSANDLTDECQLDELSGNAALNGVPVTVAAA
EEEEECCCCCCCCCCCCCCCCHHHCCCCCEECCCCEEEEEC
>Mature Secondary Structure 
TKTLHHRACHLCEAICGLTIETTETDGQVQITSIKGDALDTFSRGHICPKAVALQDIQN
CCCHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCHHHHCCCCCCCHHHHHHHHHCC
DPDRLRQPMRRVGSEWLPIEWDEAVELVAEKLSAIQERHGQNAVAVYQGNPSVHNYGLMT
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEE
HSNYFLGLLKTRNRYSATSVDQLPHHLTSYLMYGHGLLLPIPDIDHTDFMLILGGNPLAS
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCC
NGSIMTVPDVEKRLKAIQARGGKVVVVDPRRSETAAMADQHLFVRPGGDAALLFGVLNTL
CCCEEECCCHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHH
FSEGLTSDSHLPVDGLDDVRAAVAGFTAEAMSPLCAVPSEQIRQLARDFAAAPSAVCYGR
HHCCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCHHCCCHHHHHHHHHHHHCCCCHHEECC
MGVSTQAFGTLCHWVVQLINLVTGNLDRVGGALCTEPAVDLVASTSGGHFNKWQSRVSGR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCHHHHHEECCCCCCHHHHHHHHCCC
PEYGGELPVSALAEEMLTEGEGQIRALITVAGNPVLSTPNGRQLEQALDGLEFMVSVDLY
CCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCHHHHHHHCCCEEEEEEEEE
INETTRYADLILPSTSALENDHYDTTFNLFAVRNVTRFNRAILAKPEGALHDWEIFVGLA
ECCCCCEEHEECCCCHHHCCCCCCCEEEEEEEHHHHHHCCEEEECCCCCCCHHHHHHHHH
KAFAAKTGKELKPTMPPSKMIDTGLRMGAYGDASEHKLSLATLFDHPHGVDLGALKPNLT
HHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
PRLKTFNQRVQAAPPEILADLARFAALQAPAADELLMIGRRHVRSNNSWMHNYHRLVKGK
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PRHQLLMNPDDLASRGLSDGQLVRVSSRVGQIEVEVLGSADMMKGVVSLPHGWGHARPGV
CCCEECCCCHHHHHCCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCC
QMAIASGQPGSSANDLTDECQLDELSGNAALNGVPVTVAAA
EEEEECCCCCCCCCCCCCCCCHHHCCCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]