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The map label for this gene is oprD [H]

Identifier: 77460640

GI number: 77460640

Start: 4975855

End: 4977201

Strand: Direct

Name: oprD [H]

Synonym: Pfl01_4419

Alternate gene names: 77460640

Gene position: 4975855-4977201 (Clockwise)

Preceding gene: 77460636

Following gene: 77460643

Centisome position: 77.28

GC content: 57.54

Gene sequence:

>1347_bases
ATGCGCGTGATGAAGTGGAGCATGATCGCACTGGCAGTTGCAGCAGCCGCCAGTACTCAGATGGCTACGGCCGCACCGTT
CGTAAGTGACCAGGCAGAAGCCAAAGGCTTCGTTGAAGGCGCGAAAGCTGATTTGCTGATTCGCAACTATTACTTCAACC
GTGACAACAAAGACGGTGCCCGTGACGTAAAAGACTGGACCCAGGGTATCTGGGGCAACTTCAGCTCCGGTTACACCCAA
GGTACTGTTGGCGTCGGCGTTGATGCGTTCGGCTACCTGGCCATCAAACTGGACGGCGGTGCCGGCACCAGCGGCTCCGG
CAACATGAGCCGCAGCAACGAGTTCAATGCAAACGGTTCCCGCGACCCTGACGACAGCCAAGGCAAAGCCGGCGCTGCCA
TCAAGTTCCGCGTATCGAAAACCGAGCTGAAAATCGGTGACATGCAGCCTAGCACCGCTCCGGTGTTCGCTGTCGGCGGC
TCCCGTATCCTTCCGCAAACTGCCAGCGGTTTCCAACTGCAGAGCAGCGAGATCAAAGACCTTGACCTCGAAGCCGGTCA
CTTCTACTCGGCAACCAGCCAGGACCGCAACGCCCGTGAAGGTGGTCTGTACGCGACCTACGCTGGTGTTGAAGCCAACA
CCATCGACTACTTCGGTGGCAAGTACGGCATCACCGAAAACCTGAGCGCATCGCTCTACGGCGCCAAACTGGAAGACATC
TGGAACCAGTACTACGCCAACGTGAACCTGACCACTCCATTTGGTGGTGACACTTCGCTGAACACCGACTTCAACATCTA
TCGCACCACCGACACCGGTAGCGCGAAAGCCGGTGACATCAGCAACACCGCGTTCTCCCTGGCCACCGCTCTCTCGTTCC
TGAAAGCGCACACCATCACCCTGGCCTTCCAGAAGGTCAACGGCGACACTCCGTTCGACTACATCGGCGTGGGCAAGAAC
AACCGTGGCGGCGACTCGATCTTCCTCGCCAACTCCATCCAGTACTCTGACTTCAACGCCCCGGGCGAGAAGTCTGCCCA
GATCCGTTACGACATCAAAATGGCCGAGTACGGCGTTCCAGGTCTGAGCTTCATGACCCGCTACGTTAAAGGCTGGGACA
TCGACGGTACCCACACTCCAGCAGGCAGCGCCTACGCTGGTCTGTATGGCGAAGATGGCAAACACAACGAAACCAACTTC
GAAGCCAAATACGTAGTTCAGTCTGGCCCGGCCAAAGACCTGTCCTTCCGTATTCGCCAAGCCTGGCACTTCGCTAACGC
CGACGAAGGTGAAGGCGATACCAAAGAGTTCCGTCTGATCGTCGACTACCCGCTGTCGCTTTTGTAA

Upstream 100 bases:

>100_bases
GCGTGATATAAGTTTGCGCCGACACAAAAAGAAAGAGCCGCCCAGATAATAAAACAGGTGGGACGGCAGTACTCTTCTAA
AACCAAAGGAGCAAATCACG

Downstream 100 bases:

>100_bases
TCGCACCGAGTTAGTTGCGGTAACAAAACAAAAAGGCCCATCTTCGGATGGGCCTTTTTTATTGCCTGTCACTTGTAATA
GATGCCTGACCGATAAGTCA

Product: outer membrane porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRVMKWSMIALAVAAAASTQMATAAPFVSDQAEAKGFVEGAKADLLIRNYYFNRDNKDGARDVKDWTQGIWGNFSSGYTQ
GTVGVGVDAFGYLAIKLDGGAGTSGSGNMSRSNEFNANGSRDPDDSQGKAGAAIKFRVSKTELKIGDMQPSTAPVFAVGG
SRILPQTASGFQLQSSEIKDLDLEAGHFYSATSQDRNAREGGLYATYAGVEANTIDYFGGKYGITENLSASLYGAKLEDI
WNQYYANVNLTTPFGGDTSLNTDFNIYRTTDTGSAKAGDISNTAFSLATALSFLKAHTITLAFQKVNGDTPFDYIGVGKN
NRGGDSIFLANSIQYSDFNAPGEKSAQIRYDIKMAEYGVPGLSFMTRYVKGWDIDGTHTPAGSAYAGLYGEDGKHNETNF
EAKYVVQSGPAKDLSFRIRQAWHFANADEGEGDTKEFRLIVDYPLSLL

Sequences:

>Translated_448_residues
MRVMKWSMIALAVAAAASTQMATAAPFVSDQAEAKGFVEGAKADLLIRNYYFNRDNKDGARDVKDWTQGIWGNFSSGYTQ
GTVGVGVDAFGYLAIKLDGGAGTSGSGNMSRSNEFNANGSRDPDDSQGKAGAAIKFRVSKTELKIGDMQPSTAPVFAVGG
SRILPQTASGFQLQSSEIKDLDLEAGHFYSATSQDRNAREGGLYATYAGVEANTIDYFGGKYGITENLSASLYGAKLEDI
WNQYYANVNLTTPFGGDTSLNTDFNIYRTTDTGSAKAGDISNTAFSLATALSFLKAHTITLAFQKVNGDTPFDYIGVGKN
NRGGDSIFLANSIQYSDFNAPGEKSAQIRYDIKMAEYGVPGLSFMTRYVKGWDIDGTHTPAGSAYAGLYGEDGKHNETNF
EAKYVVQSGPAKDLSFRIRQAWHFANADEGEGDTKEFRLIVDYPLSLL
>Mature_448_residues
MRVMKWSMIALAVAAAASTQMATAAPFVSDQAEAKGFVEGAKADLLIRNYYFNRDNKDGARDVKDWTQGIWGNFSSGYTQ
GTVGVGVDAFGYLAIKLDGGAGTSGSGNMSRSNEFNANGSRDPDDSQGKAGAAIKFRVSKTELKIGDMQPSTAPVFAVGG
SRILPQTASGFQLQSSEIKDLDLEAGHFYSATSQDRNAREGGLYATYAGVEANTIDYFGGKYGITENLSASLYGAKLEDI
WNQYYANVNLTTPFGGDTSLNTDFNIYRTTDTGSAKAGDISNTAFSLATALSFLKAHTITLAFQKVNGDTPFDYIGVGKN
NRGGDSIFLANSIQYSDFNAPGEKSAQIRYDIKMAEYGVPGLSFMTRYVKGWDIDGTHTPAGSAYAGLYGEDGKHNETNF
EAKYVVQSGPAKDLSFRIRQAWHFANADEGEGDTKEFRLIVDYPLSLL

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 48242; Mature: 48242

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVMKWSMIALAVAAAASTQMATAAPFVSDQAEAKGFVEGAKADLLIRNYYFNRDNKDGA
CCEEHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCH
RDVKDWTQGIWGNFSSGYTQGTVGVGVDAFGYLAIKLDGGAGTSGSGNMSRSNEFNANGS
HHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
RDPDDSQGKAGAAIKFRVSKTELKIGDMQPSTAPVFAVGGSRILPQTASGFQLQSSEIKD
CCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCEEEECCCEECCCCCCCCEEECCCCCC
LDLEAGHFYSATSQDRNAREGGLYATYAGVEANTIDYFGGKYGITENLSASLYGAKLEDI
CCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEECCCHHHHH
WNQYYANVNLTTPFGGDTSLNTDFNIYRTTDTGSAKAGDISNTAFSLATALSFLKAHTIT
HHHHEECEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
LAFQKVNGDTPFDYIGVGKNNRGGDSIFLANSIQYSDFNAPGEKSAQIRYDIKMAEYGVP
EEEEECCCCCCCEEEECCCCCCCCCEEEEEECEEECCCCCCCCCCCEEEEEEEEECCCCC
GLSFMTRYVKGWDIDGTHTPAGSAYAGLYGEDGKHNETNFEAKYVVQSGPAKDLSFRIRQ
HHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
AWHFANADEGEGDTKEFRLIVDYPLSLL
HHCCCCCCCCCCCCEEEEEEEECCHHCC
>Mature Secondary Structure
MRVMKWSMIALAVAAAASTQMATAAPFVSDQAEAKGFVEGAKADLLIRNYYFNRDNKDGA
CCEEHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCH
RDVKDWTQGIWGNFSSGYTQGTVGVGVDAFGYLAIKLDGGAGTSGSGNMSRSNEFNANGS
HHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
RDPDDSQGKAGAAIKFRVSKTELKIGDMQPSTAPVFAVGGSRILPQTASGFQLQSSEIKD
CCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCEEEECCCEECCCCCCCCEEECCCCCC
LDLEAGHFYSATSQDRNAREGGLYATYAGVEANTIDYFGGKYGITENLSASLYGAKLEDI
CCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEECCCHHHHH
WNQYYANVNLTTPFGGDTSLNTDFNIYRTTDTGSAKAGDISNTAFSLATALSFLKAHTIT
HHHHEECEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
LAFQKVNGDTPFDYIGVGKNNRGGDSIFLANSIQYSDFNAPGEKSAQIRYDIKMAEYGVP
EEEEECCCCCCCEEEECCCCCCCCCEEEEEECEEECCCCCCCCCCCEEEEEEEEECCCCC
GLSFMTRYVKGWDIDGTHTPAGSAYAGLYGEDGKHNETNFEAKYVVQSGPAKDLSFRIRQ
HHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
AWHFANADEGEGDTKEFRLIVDYPLSLL
HHCCCCCCCCCCCCEEEEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]