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The map label for this gene is nadA [H]

Identifier: 77460618

GI number: 77460618

Start: 4958209

End: 4959267

Strand: Reverse

Name: nadA [H]

Synonym: Pfl01_4397

Alternate gene names: 77460618

Gene position: 4959267-4958209 (Counterclockwise)

Preceding gene: 77460619

Following gene: 77460605

Centisome position: 77.03

GC content: 61.19

Gene sequence:

>1059_bases
ATGACGCAGATTTCCGAACGCCTTCTGGTACAAGCCCACCTCGACGCCAAACAGCCCAAACCGCTGACGGCCGAGGAAGA
GGCTTATTACCGTTCCGCCATCGCCGCCGAGCTCAAGGCTCAGGACGCGGTGCTGGTTGCCCACTTTTATTGCGATCCGA
TCATCCAGGCCCTCGCCGAAGAGACCGGCGGTTGCGTTTCCGATTCACTGGAAATGGCCCGCTTCGGCAACGCCCATCCG
GCCAAGACCGTGGTGGTCGCCGGCGTGAAATTCATGGGCGAGACCGCGAAGATTCTCAACCCTGAAAAGCGCGTGCTGAT
GCCGACCCTGGAAGCGACCTGCTCGCTGGATCTGGGTTGCCCGGTGGACGAGTTCTCGGCGTTCTGCGATCAACATCCGG
AGCGCACCGTGGTGGTGTATGCCAACACCTCGGCCGCCGTCAAAGCCCGGGCCGACTGGGTGGTGACCTCCAGCTGCGCA
CTGGAAATCGTCGAAAGCCTGAAGGACAACGGCGAAACCATCATCTGGGGGCCGGACAAGCACCTGGGCACCTACATCCA
GCGTCAGACCGGCGCCGACATGCTGCTCTGGGATGGTGCATGCATCGTTCACGAGGAATTCAAGTCCAAGCAGCTGGAAG
ACATGAAAGCGCTGTACCCGGACGCCGCCATTCTGGTGCATCCGGAGTCGCCGACCTCGGTGATCGAGTTGGCGGACGCT
GTCGGTTCCACCAGTCAGTTGATTGCCGCCGCTCAATCGCTGCCGAACAAGACTTTGATCGTCGCTACCGACCGCGGCAT
CTTCTACAAGATGCAGCAGCTGTGCCCGGACAAGGTCTTCATCGAAGCGCCAACCGCCGGTAACGGCGCGGCATGCCGCA
GTTGCGCACATTGCCCGTGGATGGCCATGAACACCCTTGAGCGCACGCTCAAGTGCCTGAAGGAAGGTTCGAACGAGATC
TTTGTCGACCCGGCTCTCATTCCTCAAGCGATCCGCCCGCTCAAGCGCATGCTCGACTTCACTCAAGCCGCGCGGATGAA
ACTGGCCGGCAACGCCTGA

Upstream 100 bases:

>100_bases
CGTGCCTGATAATACTCACTCTCCCGGCGGTACCCTCAAGCGGTCCGGAGCCGGGTGTATACTCGACTTTCGCGCGAATG
CGCCTGCAGGTCTTGCGAAC

Downstream 100 bases:

>100_bases
CCTTGCGACGCAAACAAAAACGCCCCGATTGGATCGGGGCGTTTTTGCATCTGGAGGATTATTTGGCTTTCTTCGGAATT
CGCACGAGCTGCGTGTCGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTQISERLLVQAHLDAKQPKPLTAEEEAYYRSAIAAELKAQDAVLVAHFYCDPIIQALAEETGGCVSDSLEMARFGNAHP
AKTVVVAGVKFMGETAKILNPEKRVLMPTLEATCSLDLGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCA
LEIVESLKDNGETIIWGPDKHLGTYIQRQTGADMLLWDGACIVHEEFKSKQLEDMKALYPDAAILVHPESPTSVIELADA
VGSTSQLIAAAQSLPNKTLIVATDRGIFYKMQQLCPDKVFIEAPTAGNGAACRSCAHCPWMAMNTLERTLKCLKEGSNEI
FVDPALIPQAIRPLKRMLDFTQAARMKLAGNA

Sequences:

>Translated_352_residues
MTQISERLLVQAHLDAKQPKPLTAEEEAYYRSAIAAELKAQDAVLVAHFYCDPIIQALAEETGGCVSDSLEMARFGNAHP
AKTVVVAGVKFMGETAKILNPEKRVLMPTLEATCSLDLGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCA
LEIVESLKDNGETIIWGPDKHLGTYIQRQTGADMLLWDGACIVHEEFKSKQLEDMKALYPDAAILVHPESPTSVIELADA
VGSTSQLIAAAQSLPNKTLIVATDRGIFYKMQQLCPDKVFIEAPTAGNGAACRSCAHCPWMAMNTLERTLKCLKEGSNEI
FVDPALIPQAIRPLKRMLDFTQAARMKLAGNA
>Mature_351_residues
TQISERLLVQAHLDAKQPKPLTAEEEAYYRSAIAAELKAQDAVLVAHFYCDPIIQALAEETGGCVSDSLEMARFGNAHPA
KTVVVAGVKFMGETAKILNPEKRVLMPTLEATCSLDLGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCAL
EIVESLKDNGETIIWGPDKHLGTYIQRQTGADMLLWDGACIVHEEFKSKQLEDMKALYPDAAILVHPESPTSVIELADAV
GSTSQLIAAAQSLPNKTLIVATDRGIFYKMQQLCPDKVFIEAPTAGNGAACRSCAHCPWMAMNTLERTLKCLKEGSNEIF
VDPALIPQAIRPLKRMLDFTQAARMKLAGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=330, Percent_Identity=68.1818181818182, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38293; Mature: 38162

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQISERLLVQAHLDAKQPKPLTAEEEAYYRSAIAAELKAQDAVLVAHFYCDPIIQALAE
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
ETGGCVSDSLEMARFGNAHPAKTVVVAGVKFMGETAKILNPEKRVLMPTLEATCSLDLGC
HHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCHHEEEECHHHHEEECCCC
PVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCALEIVESLKDNGETIIWGPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHCCCCEEEECCCH
HLGTYIQRQTGADMLLWDGACIVHEEFKSKQLEDMKALYPDAAILVHPESPTSVIELADA
HHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIAAAQSLPNKTLIVATDRGIFYKMQQLCPDKVFIEAPTAGNGAACRSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCH
MAMNTLERTLKCLKEGSNEIFVDPALIPQAIRPLKRMLDFTQAARMKLAGNA
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQISERLLVQAHLDAKQPKPLTAEEEAYYRSAIAAELKAQDAVLVAHFYCDPIIQALAE
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHH
ETGGCVSDSLEMARFGNAHPAKTVVVAGVKFMGETAKILNPEKRVLMPTLEATCSLDLGC
HHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCHHEEEECHHHHEEECCCC
PVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCALEIVESLKDNGETIIWGPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHCCCCEEEECCCH
HLGTYIQRQTGADMLLWDGACIVHEEFKSKQLEDMKALYPDAAILVHPESPTSVIELADA
HHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIAAAQSLPNKTLIVATDRGIFYKMQQLCPDKVFIEAPTAGNGAACRSCAHCPW
HCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCH
MAMNTLERTLKCLKEGSNEIFVDPALIPQAIRPLKRMLDFTQAARMKLAGNA
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA