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The map label for this gene is arcD [H]

Identifier: 77460605

GI number: 77460605

Start: 4941766

End: 4943193

Strand: Reverse

Name: arcD [H]

Synonym: Pfl01_4384

Alternate gene names: 77460605

Gene position: 4943193-4941766 (Counterclockwise)

Preceding gene: 77460618

Following gene: 77460596

Centisome position: 76.78

GC content: 60.92

Gene sequence:

>1428_bases
ATGTCGCAACCGACGCAAAAACTGCGCCTTGGCGCACTGATCGCCCTGGTGGTGGGTTCGATGATTGGCGGGGGGATTTT
TTCCTTGCCGCAAAACATGGCAGCCCGGGCCGATGCCGGCGCCATCCTGATCGGCTGGGGCATCACGGCGATCGGCATGC
TCACCCTGGCGTTCGTGTTCCAGACTTTGGCCAATCGCAAGCCGGAACTGGACTCCGGCGTGTATGCCTACGCCAAGGCC
GGGTTCGGCGATTACATGGGCTTTTCTTCCGCGTGGGGTTACTGGATCAGCGCCTGGCTGGGCAACGTCGGGTATTTCGT
GTTGCTGTTCAGCACCCTCGGCTACTTCTTTCCGGTATTCGGCCAGGGCAATACGCCGATTGCGATTGGCTGCGCTTCGG
TGTTGCTGTGGGCCGTGCACTTTCTGGTGATGCGCGGGATCAAGGAAGCCGCGCTGATCAATCAGTTGACCACCGTGGCC
AAGATCATTCCGCTGATCATGTTCGTGGTCATCGCCGCCGTGGCGTTCAAGGCTGACGTGTTTACCCGCGACATCTGGGG
CCGCAGCAACCCGAATTTCGGCGGTGTGATGGATCAGGTGCGCAACATGATGCTGGTCACCGTGTTCGTGTTCATCGGTA
TCGAAGGCGCCAGCGTTTACTCGGCCCGGGCGGAGAAGCGCACCGACGTGGGCCGTGCCACGGTGATCGGTTTCCTCGGT
GTGCTGGCGCTGCTGGTGCTGGTCAATGTGTTGTCGCTGGGGATCATGAGCCAACCGGAACTGGCGACCTTGCAGAACCC
GTCGCTGGCCGCCGTGCTGGAACACATCGTCGGGCCCTGGGGCGCGCTGCTGATCAGCGTGGGCCTGGCCATTTCATTGC
TCGGTGCGTTGCTGTCGTGGGCGCTGTTGTGCGCCGAGATCCTGTTCGCCACTGCCAAGGACAACACGATGCCGGCGTTC
CTGAAAAAGGAAAACGCCAACCATGTGCCGGTCAATGCGTTGTGGCTGACCAACGTGATGATCCAGATTTTCCTGCTGAT
CACGCTGTTTTCCGCCGGTACTTACACCAGCCTGATTTACCTCGCCTCGTCGATGATTCTGGTGCCGTATCTGTGGTCGG
CAGCCTACGCCGTGTTACTCAGCGGACGGGGTGAGACCTATGAACATGCCTCCGCCGAACGTACCAAGGATCTGCTGATC
GGCGGTATCGCGCTGTGCTACGCGGTGTGGCTGTTGTATGCCGGCGGGGTGAAATACCTGCTGCTGTCGGCGCTGTTGTA
TGCGCCGGGCGTGATCCTGTTCGCCAAGGCCAAGCATGAGCAGGGCGAGCCGTTGTTCACCACGCTCGAGAAGGGGATTT
TCACCTGCGTCATCGCCGGGGCCGGGCTTGCGGCCTACGGGTTGTACAGCGGCGTGTTGTCCCTGTGA

Upstream 100 bases:

>100_bases
CGTTATTCAATAAACGTACTTACGCTCTAACCGTTTGGTTAATACCGGTTACATGACCATGGGCGGCCAATGCCGACCTC
GGGAACCTGGAGACGCTGGA

Downstream 100 bases:

>100_bases
GATTGCGGCTCGACTTTCAGGGGCCTTACGACTGGCCGGCGATGCTCGGGTTTCTCGCGAAAACGGTGGAGAGGTCACCA
CTGCGCCCGATGTGAACCCA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSQPTQKLRLGALIALVVGSMIGGGIFSLPQNMAARADAGAILIGWGITAIGMLTLAFVFQTLANRKPELDSGVYAYAKA
GFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGQGNTPIAIGCASVLLWAVHFLVMRGIKEAALINQLTTVA
KIIPLIMFVVIAAVAFKADVFTRDIWGRSNPNFGGVMDQVRNMMLVTVFVFIGIEGASVYSARAEKRTDVGRATVIGFLG
VLALLVLVNVLSLGIMSQPELATLQNPSLAAVLEHIVGPWGALLISVGLAISLLGALLSWALLCAEILFATAKDNTMPAF
LKKENANHVPVNALWLTNVMIQIFLLITLFSAGTYTSLIYLASSMILVPYLWSAAYAVLLSGRGETYEHASAERTKDLLI
GGIALCYAVWLLYAGGVKYLLLSALLYAPGVILFAKAKHEQGEPLFTTLEKGIFTCVIAGAGLAAYGLYSGVLSL

Sequences:

>Translated_475_residues
MSQPTQKLRLGALIALVVGSMIGGGIFSLPQNMAARADAGAILIGWGITAIGMLTLAFVFQTLANRKPELDSGVYAYAKA
GFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGQGNTPIAIGCASVLLWAVHFLVMRGIKEAALINQLTTVA
KIIPLIMFVVIAAVAFKADVFTRDIWGRSNPNFGGVMDQVRNMMLVTVFVFIGIEGASVYSARAEKRTDVGRATVIGFLG
VLALLVLVNVLSLGIMSQPELATLQNPSLAAVLEHIVGPWGALLISVGLAISLLGALLSWALLCAEILFATAKDNTMPAF
LKKENANHVPVNALWLTNVMIQIFLLITLFSAGTYTSLIYLASSMILVPYLWSAAYAVLLSGRGETYEHASAERTKDLLI
GGIALCYAVWLLYAGGVKYLLLSALLYAPGVILFAKAKHEQGEPLFTTLEKGIFTCVIAGAGLAAYGLYSGVLSL
>Mature_474_residues
SQPTQKLRLGALIALVVGSMIGGGIFSLPQNMAARADAGAILIGWGITAIGMLTLAFVFQTLANRKPELDSGVYAYAKAG
FGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGQGNTPIAIGCASVLLWAVHFLVMRGIKEAALINQLTTVAK
IIPLIMFVVIAAVAFKADVFTRDIWGRSNPNFGGVMDQVRNMMLVTVFVFIGIEGASVYSARAEKRTDVGRATVIGFLGV
LALLVLVNVLSLGIMSQPELATLQNPSLAAVLEHIVGPWGALLISVGLAISLLGALLSWALLCAEILFATAKDNTMPAFL
KKENANHVPVNALWLTNVMIQIFLLITLFSAGTYTSLIYLASSMILVPYLWSAAYAVLLSGRGETYEHASAERTKDLLIG
GIALCYAVWLLYAGGVKYLLLSALLYAPGVILFAKAKHEQGEPLFTTLEKGIFTCVIAGAGLAAYGLYSGVLSL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=448, Percent_Identity=45.7589285714286, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI2367353, Length=421, Percent_Identity=28.5035629453682, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1790575, Length=387, Percent_Identity=27.906976744186, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786908, Length=435, Percent_Identity=24.5977011494253, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50736; Mature: 50605

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTQKLRLGALIALVVGSMIGGGIFSLPQNMAARADAGAILIGWGITAIGMLTLAFVF
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
QTLANRKPELDSGVYAYAKAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVF
HHHHCCCCCCCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GQGNTPIAIGCASVLLWAVHFLVMRGIKEAALINQLTTVAKIIPLIMFVVIAAVAFKADV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTRDIWGRSNPNFGGVMDQVRNMMLVTVFVFIGIEGASVYSARAEKRTDVGRATVIGFLG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLALLVLVNVLSLGIMSQPELATLQNPSLAAVLEHIVGPWGALLISVGLAISLLGALLSW
HHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
ALLCAEILFATAKDNTMPAFLKKENANHVPVNALWLTNVMIQIFLLITLFSAGTYTSLIY
HHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LASSMILVPYLWSAAYAVLLSGRGETYEHASAERTKDLLIGGIALCYAVWLLYAGGVKYL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLSALLYAPGVILFAKAKHEQGEPLFTTLEKGIFTCVIAGAGLAAYGLYSGVLSL
HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQPTQKLRLGALIALVVGSMIGGGIFSLPQNMAARADAGAILIGWGITAIGMLTLAFVF
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH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HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]