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The map label for this gene is gap [H]

Identifier: 77460597

GI number: 77460597

Start: 4931279

End: 4932280

Strand: Direct

Name: gap [H]

Synonym: Pfl01_4376

Alternate gene names: 77460597

Gene position: 4931279-4932280 (Clockwise)

Preceding gene: 77460585

Following gene: 77460598

Centisome position: 76.59

GC content: 59.88

Gene sequence:

>1002_bases
ATGACTCTTCGAATCGCAATCAATGGTTTTGGCCGCATCGGCCGTAATGTCCTGCGCGCACTGTATACCCAAGGCTATCG
TCAGGATTTGCAGATCGTCGCCATCAACGATCTGGGCGACAGCGCGATTAATGCGCATCTGCTCAAGTACGACACCGTTC
ATGGCACATTCGACGCCGAAGTGGCTCATGACAACGAGAGCCTGACCGTCAACGGCGACCGCATTTCGGTCAGCGCCATC
CGCAACCCGGCCGACCTGCCATGGGCCGCGGAAAAGATTGATGTGGTGTTCGAATGCACCGGTCTGTTCACCGACCGGGC
CAAAGCCGCTGCGCATATTACCGCCGGCGCACGCAAAGTGATTATCTCGGCCCCGGCCAAAGGCGCCGATGCCACCGTCG
TTTACGGTGTGAACCACGACATTCTGCGCCAGTCGCACCAGATCATTTCCAACGCGTCGTGCACCACCAACTGCCTCGCG
CCAGTCGCGCAAGTGCTGCACCGCGAGTTGGGCATCGAAAGCGGTCTGATGACCACGATTCACGCCTATACCAACGACCA
GAACCTGACCGACGTTTATCACACCGACCCGTACCGCGCGCGCTCCGCCACCCAGAACATGATCCCGAGCAAGACCGGCG
CTGCCGAAGCCGTGGGCCTGGTGCTGCCGGAACTGGCCGGCAAGCTGACCGGCATGGCCGTGCGTGTACCGGTGATCAAT
GTGTCGCTGGTTGACCTGACCGTGCAGCTGAAGCGCGAAGCCTCGGCCGATGAAGTGAACGCCCTGATGAAAGCCGCGAG
CCAGCATTCGAAGATCCTCGGCTTCAACACCCTGCCGCTGGTATCGAGCGACTTCAATCACAACCCACTGTCGTCGATCT
TCGACGCCAACCACACCAAAGCCAGCGGCAAACTGCTGAAAGTGCTGGCCTGGTACGACAACGAGTGGGGCTTCTCCAAC
CGCATGCTCGATAACTGCCTGGCGCTGTGCAACGCGGAATAA

Upstream 100 bases:

>100_bases
TTGTAGATAAAACAAAATATTGCCACTAAAAAGGCTTGTTTTCTATTTTTATGCGAATAATCTTGTAATTCCAACAACAA
AACGACGGCGGCGCTGTTCA

Downstream 100 bases:

>100_bases
TCCCCCGCCCCTGATTCCTGTGGGAGCTGGCTTGCCAGCGATGAAGTCGGCACATCCAATATGGATATCCGCTGACCCAC
CTCTATCGCTGGCAAGCCAG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQIVAINDLGDSAINAHLLKYDTVHGTFDAEVAHDNESLTVNGDRISVSAI
RNPADLPWAAEKIDVVFECTGLFTDRAKAAAHITAGARKVIISAPAKGADATVVYGVNHDILRQSHQIISNASCTTNCLA
PVAQVLHRELGIESGLMTTIHAYTNDQNLTDVYHTDPYRARSATQNMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
VSLVDLTVQLKREASADEVNALMKAASQHSKILGFNTLPLVSSDFNHNPLSSIFDANHTKASGKLLKVLAWYDNEWGFSN
RMLDNCLALCNAE

Sequences:

>Translated_333_residues
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQIVAINDLGDSAINAHLLKYDTVHGTFDAEVAHDNESLTVNGDRISVSAI
RNPADLPWAAEKIDVVFECTGLFTDRAKAAAHITAGARKVIISAPAKGADATVVYGVNHDILRQSHQIISNASCTTNCLA
PVAQVLHRELGIESGLMTTIHAYTNDQNLTDVYHTDPYRARSATQNMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
VSLVDLTVQLKREASADEVNALMKAASQHSKILGFNTLPLVSSDFNHNPLSSIFDANHTKASGKLLKVLAWYDNEWGFSN
RMLDNCLALCNAE
>Mature_332_residues
TLRIAINGFGRIGRNVLRALYTQGYRQDLQIVAINDLGDSAINAHLLKYDTVHGTFDAEVAHDNESLTVNGDRISVSAIR
NPADLPWAAEKIDVVFECTGLFTDRAKAAAHITAGARKVIISAPAKGADATVVYGVNHDILRQSHQIISNASCTTNCLAP
VAQVLHRELGIESGLMTTIHAYTNDQNLTDVYHTDPYRARSATQNMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVINV
SLVDLTVQLKREASADEVNALMKAASQHSKILGFNTLPLVSSDFNHNPLSSIFDANHTKASGKLLKVLAWYDNEWGFSNR
MLDNCLALCNAE

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=328, Percent_Identity=47.5609756097561, Blast_Score=285, Evalue=4e-77,
Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=44.8170731707317, Blast_Score=258, Evalue=5e-69,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=51.0510510510511, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=50, Blast_Score=304, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=47.1299093655589, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=47.1299093655589, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=46.8277945619335, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=46.8277945619335, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=327, Percent_Identity=48.9296636085627, Blast_Score=304, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=47.4006116207951, Blast_Score=298, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=47.112462006079, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=47.7064220183486, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=47.7064220183486, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=47.4006116207951, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=47.4006116207951, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=45.7055214723926, Blast_Score=268, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35997; Mature: 35866

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRIAINGFGRIGRNVLRALYTQGYRQDLQIVAINDLGDSAINAHLLKYDTVHGTFDAE
CEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHEEEEEEECCCCCEECE
VAHDNESLTVNGDRISVSAIRNPADLPWAAEKIDVVFECTGLFTDRAKAAAHITAGARKV
EECCCCEEEEECCEEEEEECCCCCCCCCCHHHEEEEEEEECCHHHHHHHHEEEECCCEEE
IISAPAKGADATVVYGVNHDILRQSHQIISNASCTTNCLAPVAQVLHRELGIESGLMTTI
EEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQNLTDVYHTDPYRARSATQNMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
EEECCCCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEE
VSLVDLTVQLKREASADEVNALMKAASQHSKILGFNTLPLVSSDFNHNPLSSIFDANHTK
EEEEEEEEEEHHCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCC
ASGKLLKVLAWYDNEWGFSNRMLDNCLALCNAE
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLRIAINGFGRIGRNVLRALYTQGYRQDLQIVAINDLGDSAINAHLLKYDTVHGTFDAE
EEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHEEEEEEECCCCCEECE
VAHDNESLTVNGDRISVSAIRNPADLPWAAEKIDVVFECTGLFTDRAKAAAHITAGARKV
EECCCCEEEEECCEEEEEECCCCCCCCCCHHHEEEEEEEECCHHHHHHHHEEEECCCEEE
IISAPAKGADATVVYGVNHDILRQSHQIISNASCTTNCLAPVAQVLHRELGIESGLMTTI
EEECCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQNLTDVYHTDPYRARSATQNMIPSKTGAAEAVGLVLPELAGKLTGMAVRVPVIN
EEECCCCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEE
VSLVDLTVQLKREASADEVNALMKAASQHSKILGFNTLPLVSSDFNHNPLSSIFDANHTK
EEEEEEEEEEHHCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCC
ASGKLLKVLAWYDNEWGFSNRMLDNCLALCNAE
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]