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The map label for this gene is gnuT [H]

Identifier: 77460556

GI number: 77460556

Start: 4888908

End: 4890260

Strand: Reverse

Name: gnuT [H]

Synonym: Pfl01_4335

Alternate gene names: 77460556

Gene position: 4890260-4888908 (Counterclockwise)

Preceding gene: 77460557

Following gene: 77460554

Centisome position: 75.95

GC content: 62.31

Gene sequence:

>1353_bases
ATGTTTGGCATGTCCCATGACGCCTACCTGCTGCTCGATGCAGTGGTTACGGTGATCGGACTCATCGTCCTGATCACCAA
GTTCAAGATTCACCCCTTCATTGCCCTGACCATCGCCGCCGCGTTCCTTGGCCTGACGTCCGGCATGCCGATCGGCACGA
TCATCAAGGCGTTCCAGGACGGCTTCGGTGGCGTGCTCGGTTTTGTCGGCATCATCCTCGCCCTGGGCACGATGCTCGGC
AAGATGATGGCCGAATCCGGTGGTGCCGATCAGATCGCCCAGACCCTGATCCGCGCCTTCGGCAAGGACAAGGTGCAGTG
GGCGATGATGTTCGCCGCGTTCCTGGTGGGCATTCCGCTGTTCTTCGAAATCGGCTTCGTGTTGCTGATTCCGCTGGTGT
TCATCGTGGCTCGCCGCACTGGTGTGTCGATCATCAAGATCGGTATCCCGCTGCTCGCCGGTCTGTCCGCCGTGCACGGC
TTGGTGCCGCCGCACCCGGGCCCGCTGCTGGCCATCGGCGTGTTCGGTGCCGACATCGGCAAGACCATTCTGTACGGTCT
GATCGTCGCGCTGCCGACCGCCATCATCGCCGGCCCGATCTTCGGTACGTTCATCGCCAAGCACATTCCCGGTACGCCGA
ACCAGGAACTGGTCGATCAACTGGCCCGTGAAAACGATTCGGCCAACCTGCCGAGCTTCAGCATCACCCTGGTCACCGTG
CTGCTGCCGGTGTTCCTGATGCTGCTGAAAACCTTCGCTGACGTGGCCCTGCCGGACGGTCATTTCTTCCGCACCTGGAT
GGACATGATCGGTCACCCGATCTCGGCACTGCTGCTGGCATTGCTGCTGTCGCTGTACACCTTCGGTCACAAGCAGGGCA
TCGGTTCTCAGCAGATGCTCAAATGGCTGGACGCGAGCCTGGCGCCGACCGCGGCAATCATTCTGATCATCGGCGCCGGC
GGTGGCTTCAAGCAGATGCTGGTGACCAGCGGCGTGGGCGACGTGATCGGCCACATGGCGGTCAGCGCGCAGATCTCGCC
GATCCTGCTGGCGTGGCTGGTGGCGGCGGTGATCCGCATCGCGACCGGTTCGGCCACCGTGGCGACCATCACTGGCGCGG
GCATCGTGGTGCCGGTGGTGGGGATGATCCCGGGCGTGAACCGTGAGCTGCTGGTGCTGGCCACCGGTGCCGGTTCGCTG
ATCCTGTCCCACGTCAACGACGCCGGTTTCTGGCTGGTGAAGCAGTACTTCAACATGACCGTGGCCGAGACCTTCAAGAC
CTGGACGGCGATGGAAACCATCCTGTCGGTGGTGGGGCTGGGCTTTATTCTGTTGTTGTCGCTGTTCGTTTAA

Upstream 100 bases:

>100_bases
TGAAACAGGCGGTATGAGTGTGATTGTGAAGACAGCGCTGTCCTTTCGACTTCTGATTAACCCGCTTTAATAACAACAAC
AAACCAGGAGACACCCCCTC

Downstream 100 bases:

>100_bases
GACTCTCTTCGTTCAAGAAGATGCAGACACAAAAAAACCGCAGTGATGCGGTTTTTTTGTGGGTGCAATTCGCGAGTTAC
TTGGTGCCCAGAGCATCCGC

Product: gluconate transporter

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFGMSHDAYLLLDAVVTVIGLIVLITKFKIHPFIALTIAAAFLGLTSGMPIGTIIKAFQDGFGGVLGFVGIILALGTMLG
KMMAESGGADQIAQTLIRAFGKDKVQWAMMFAAFLVGIPLFFEIGFVLLIPLVFIVARRTGVSIIKIGIPLLAGLSAVHG
LVPPHPGPLLAIGVFGADIGKTILYGLIVALPTAIIAGPIFGTFIAKHIPGTPNQELVDQLARENDSANLPSFSITLVTV
LLPVFLMLLKTFADVALPDGHFFRTWMDMIGHPISALLLALLLSLYTFGHKQGIGSQQMLKWLDASLAPTAAIILIIGAG
GGFKQMLVTSGVGDVIGHMAVSAQISPILLAWLVAAVIRIATGSATVATITGAGIVVPVVGMIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTAMETILSVVGLGFILLLSLFV

Sequences:

>Translated_450_residues
MFGMSHDAYLLLDAVVTVIGLIVLITKFKIHPFIALTIAAAFLGLTSGMPIGTIIKAFQDGFGGVLGFVGIILALGTMLG
KMMAESGGADQIAQTLIRAFGKDKVQWAMMFAAFLVGIPLFFEIGFVLLIPLVFIVARRTGVSIIKIGIPLLAGLSAVHG
LVPPHPGPLLAIGVFGADIGKTILYGLIVALPTAIIAGPIFGTFIAKHIPGTPNQELVDQLARENDSANLPSFSITLVTV
LLPVFLMLLKTFADVALPDGHFFRTWMDMIGHPISALLLALLLSLYTFGHKQGIGSQQMLKWLDASLAPTAAIILIIGAG
GGFKQMLVTSGVGDVIGHMAVSAQISPILLAWLVAAVIRIATGSATVATITGAGIVVPVVGMIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTAMETILSVVGLGFILLLSLFV
>Mature_450_residues
MFGMSHDAYLLLDAVVTVIGLIVLITKFKIHPFIALTIAAAFLGLTSGMPIGTIIKAFQDGFGGVLGFVGIILALGTMLG
KMMAESGGADQIAQTLIRAFGKDKVQWAMMFAAFLVGIPLFFEIGFVLLIPLVFIVARRTGVSIIKIGIPLLAGLSAVHG
LVPPHPGPLLAIGVFGADIGKTILYGLIVALPTAIIAGPIFGTFIAKHIPGTPNQELVDQLARENDSANLPSFSITLVTV
LLPVFLMLLKTFADVALPDGHFFRTWMDMIGHPISALLLALLLSLYTFGHKQGIGSQQMLKWLDASLAPTAAIILIIGAG
GGFKQMLVTSGVGDVIGHMAVSAQISPILLAWLVAAVIRIATGSATVATITGAGIVVPVVGMIPGVNRELLVLATGAGSL
ILSHVNDAGFWLVKQYFNMTVAETFKTWTAMETILSVVGLGFILLLSLFV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=436, Percent_Identity=46.1009174311927, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1790716, Length=420, Percent_Identity=42.6190476190476, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI2367370, Length=426, Percent_Identity=41.7840375586854, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1788707, Length=448, Percent_Identity=39.5089285714286, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1790776, Length=433, Percent_Identity=37.4133949191686, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI48994939, Length=433, Percent_Identity=39.9538106235566, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1789097, Length=443, Percent_Identity=33.8600451467269, Blast_Score=238, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47270; Mature: 47270

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]