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The map label for this gene is dgoT [H]

Identifier: 77460343

GI number: 77460343

Start: 4663800

End: 4665110

Strand: Reverse

Name: dgoT [H]

Synonym: Pfl01_4122

Alternate gene names: 77460343

Gene position: 4665110-4663800 (Counterclockwise)

Preceding gene: 77460344

Following gene: 77460342

Centisome position: 72.46

GC content: 62.24

Gene sequence:

>1311_bases
ATGCAACCGCAAACCCTCACCGGGCAAGCGACGTTAGTCACGCCCAGCCGCAAGCGATTTTTCATCATGGTGTTGCTGTT
CATCACCGTGGTCATCAACTACCTCGACCGCAGCAACCTGTCGATTGCCGCCCCGGCTCTGACGACGGATCTGGGCATCG
ACCCGGTGCACGTCGGGCTGATCTTCTCGGCGTTCGGCTGGACCTACGCCGCCATGCAGATCCCCGGCGGCTGGCTGGTG
GACCGGGTGCCGCCGCGCATCCTTTATAGCGTCGCACTGTTGCTGTGGTCGCTGGCTACGGTGATGCTCGGGTTCGCCGC
CAGTTTCATCGCGCTGTTCGTGCTGCGCATGGCGGTCGGTGCGCTGGAAGCGCCGGCGTATCCGATCAACAGCCGCGTGG
TGACGACCTGGTTCCCCGAGCGTGAGCGGGCCACGGCCATCGGTTTCTACACCTCCGGGCAGTTTGTCGGGCTGGCGTTT
CTGACCCCGGTGCTGGCGTGGCTGCAGCATGAATTTGGCTGGCACATGGTGTTTGTCGTGACCGGCGCGGTAGGCATCAT
CTGGGCGGCGATCTGGTACGCGGTGTATCGCGAGCCGCGTGATTTCAAAGGCGCCAACCAAGGCGAAATCGACCTGATCC
GCGAGGGCGGCGGGTTGGTGGACATCGCCGCCGAAACCGCCAAGGTGAAGGCGAAATTCAGCTGGACCGATCTCGGCATC
GTCCTCAGTAAACGCAAGTTGTGGGGGATCTACCTCGGCCAGTTCTGCCTCAACTCGACGCTGTGGTTTTTCCTGACGTG
GTTCCCGACCTACCTGGTGAAGTATCGCGGCATGGACTTCATCAAGTCCGGTCTGCTGGCGTCGCTGCCGTTTCTCGCCG
CGTTCATCGGCGTGCTGTGCTCCGGGTTCTTTTCCGACTTCCTGATCCGTCGCGGCTGCACCGTCGGGTTTGCGCGCAAG
CTGCCGATCATTGGCGGGCTGCTGATTTCCACCTCGATCATTGGTGCCAACTTCGTCGAGTCGACGCCGTTGGTGATTGC
CTTCCTGGCCTTGGCGTTTTTCGGCAACGGGTTGGCGTCGATCACCTGGTCGCTGGTCTCGACACTGGCGCCGGCGCGGT
TGCTGGGCTTGACCGGTGGGGTGTTCAACTTCATCGGCAACCTGTCGGCGATTGCCACGCCGATTGTCATCGGCTTCCTC
GCCAGCGGCGATTCGTTCGCTCCGGCGATCACCTACATCGCGGTTCTGGCATTGATCGGTGCTTTGTCCTACGTGCTGCT
GGTGGGCAAGGTCGAGCGCATCGAGTTGTAG

Upstream 100 bases:

>100_bases
TGAGTCGCTGACTCTCTGCCGCATCCAGTAAGTCAGATCTCCAGGGAGCGGAGATCTGCATAACCCTCGACCTCAATAAA
CATAAAAAGAGGCGCTCCCC

Downstream 100 bases:

>100_bases
TCGGCTATGTCGGGCGACCATAATGCCGCCCGTTCCCTCGCTCAACGCTAAAGGCTGGATATGCAGGAAGACGCCCCGAA
AACCGCCAAGGACGCCGCGC

Product: D-galactonate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MQPQTLTGQATLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTTDLGIDPVHVGLIFSAFGWTYAAMQIPGGWLV
DRVPPRILYSVALLLWSLATVMLGFAASFIALFVLRMAVGALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAF
LTPVLAWLQHEFGWHMVFVVTGAVGIIWAAIWYAVYREPRDFKGANQGEIDLIREGGGLVDIAAETAKVKAKFSWTDLGI
VLSKRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFIGVLCSGFFSDFLIRRGCTVGFARK
LPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLASITWSLVSTLAPARLLGLTGGVFNFIGNLSAIATPIVIGFL
ASGDSFAPAITYIAVLALIGALSYVLLVGKVERIEL

Sequences:

>Translated_436_residues
MQPQTLTGQATLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTTDLGIDPVHVGLIFSAFGWTYAAMQIPGGWLV
DRVPPRILYSVALLLWSLATVMLGFAASFIALFVLRMAVGALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAF
LTPVLAWLQHEFGWHMVFVVTGAVGIIWAAIWYAVYREPRDFKGANQGEIDLIREGGGLVDIAAETAKVKAKFSWTDLGI
VLSKRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFIGVLCSGFFSDFLIRRGCTVGFARK
LPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLASITWSLVSTLAPARLLGLTGGVFNFIGNLSAIATPIVIGFL
ASGDSFAPAITYIAVLALIGALSYVLLVGKVERIEL
>Mature_436_residues
MQPQTLTGQATLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTTDLGIDPVHVGLIFSAFGWTYAAMQIPGGWLV
DRVPPRILYSVALLLWSLATVMLGFAASFIALFVLRMAVGALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAF
LTPVLAWLQHEFGWHMVFVVTGAVGIIWAAIWYAVYREPRDFKGANQGEIDLIREGGGLVDIAAETAKVKAKFSWTDLGI
VLSKRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFIGVLCSGFFSDFLIRRGCTVGFARK
LPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLASITWSLVSTLAPARLLGLTGGVFNFIGNLSAIATPIVIGFL
ASGDSFAPAITYIAVLALIGALSYVLLVGKVERIEL

Specific function: Intake of galactonate into the cell [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=413, Percent_Identity=24.9394673123487, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI9945322, Length=404, Percent_Identity=26.980198019802, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI21322234, Length=405, Percent_Identity=25.679012345679, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI154350196, Length=414, Percent_Identity=24.3961352657005, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI148743791, Length=378, Percent_Identity=24.8677248677249, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=23.8461538461538, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI5031955, Length=284, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI148728191, Length=274, Percent_Identity=25.1824817518248, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4885441, Length=362, Percent_Identity=22.9281767955801, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI223718438, Length=192, Percent_Identity=27.0833333333333, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082320, Length=421, Percent_Identity=55.8194774346793, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=42.4311926605505, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=40.8352668213457, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI2367379, Length=432, Percent_Identity=30.0925925925926, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI2367193, Length=409, Percent_Identity=28.6063569682152, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788573, Length=411, Percent_Identity=23.3576642335766, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082071, Length=301, Percent_Identity=21.5946843853821, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=447, Percent_Identity=24.1610738255034, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533554, Length=433, Percent_Identity=24.0184757505774, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17554148, Length=361, Percent_Identity=26.5927977839335, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17552542, Length=328, Percent_Identity=24.0853658536585, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17554962, Length=378, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71997452, Length=410, Percent_Identity=22.9268292682927, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=369, Percent_Identity=25.2032520325203, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI86561091, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141318, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=245, Percent_Identity=27.7551020408163, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141341, Length=241, Percent_Identity=28.2157676348548, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540458, Length=315, Percent_Identity=23.4920634920635, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17569727, Length=403, Percent_Identity=24.317617866005, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=386, Percent_Identity=23.5751295336788, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71991453, Length=386, Percent_Identity=23.5751295336788, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565914, Length=406, Percent_Identity=22.4137931034483, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193205400, Length=237, Percent_Identity=22.7848101265823, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=248, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658658, Length=441, Percent_Identity=25.1700680272109, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24655271, Length=405, Percent_Identity=22.962962962963, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20130135, Length=405, Percent_Identity=22.962962962963, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45550460, Length=403, Percent_Identity=23.8213399503722, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573299, Length=407, Percent_Identity=25.0614250614251, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648416, Length=416, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356189, Length=416, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639764, Length=412, Percent_Identity=24.7572815533981, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655255, Length=352, Percent_Identity=23.8636363636364, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24641682, Length=390, Percent_Identity=24.8717948717949, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573708, Length=419, Percent_Identity=23.8663484486874, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28573707, Length=419, Percent_Identity=23.8663484486874, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20129235, Length=275, Percent_Identity=26.5454545454545, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20130167, Length=437, Percent_Identity=22.883295194508, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62484226, Length=436, Percent_Identity=22.2477064220184, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653727, Length=393, Percent_Identity=22.1374045801527, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654215, Length=447, Percent_Identity=22.1476510067114, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583789, Length=358, Percent_Identity=22.3463687150838, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922400, Length=447, Percent_Identity=22.1476510067114, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580790, Length=363, Percent_Identity=22.3140495867769, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920686, Length=327, Percent_Identity=23.8532110091743, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361682, Length=337, Percent_Identity=23.1454005934718, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47427; Mature: 47427

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPQTLTGQATLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTTDLGIDPVHVGL
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCHHHHHH
IFSAFGWTYAAMQIPGGWLVDRVPPRILYSVALLLWSLATVMLGFAASFIALFVLRMAVG
HHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAFLTPVLAWLQHEFGWHMVFVV
HHCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEHHH
TGAVGIIWAAIWYAVYREPRDFKGANQGEIDLIREGGGLVDIAAETAKVKAKFSWTDLGI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECHHHHEEEEEEEEHHHH
VLSKRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFIGVLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SGFFSDFLIRRGCTVGFARKLPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLAS
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHH
ITWSLVSTLAPARLLGLTGGVFNFIGNLSAIATPIVIGFLASGDSFAPAITYIAVLALIG
HHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALSYVLLVGKVERIEL
HHHHHHHHCCHHHCCC
>Mature Secondary Structure
MQPQTLTGQATLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTTDLGIDPVHVGL
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCHHHHHH
IFSAFGWTYAAMQIPGGWLVDRVPPRILYSVALLLWSLATVMLGFAASFIALFVLRMAVG
HHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAFLTPVLAWLQHEFGWHMVFVV
HHCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEHHH
TGAVGIIWAAIWYAVYREPRDFKGANQGEIDLIREGGGLVDIAAETAKVKAKFSWTDLGI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEECHHHHEEEEEEEEHHHH
VLSKRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFIGVLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SGFFSDFLIRRGCTVGFARKLPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLAS
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCHHH
ITWSLVSTLAPARLLGLTGGVFNFIGNLSAIATPIVIGFLASGDSFAPAITYIAVLALIG
HHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ALSYVLLVGKVERIEL
HHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]