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The map label for this gene is lolA

Identifier: 77459807

GI number: 77459807

Start: 4050811

End: 4051431

Strand: Reverse

Name: lolA

Synonym: Pfl01_3585

Alternate gene names: 77459807

Gene position: 4051431-4050811 (Counterclockwise)

Preceding gene: 77459808

Following gene: 77459806

Centisome position: 62.93

GC content: 59.1

Gene sequence:

>621_bases
ATGCGTCTTATCCGCATGTTGCTGCCGGTACTGGCTCTGACCACCCTCACGGCTCACGCCGATGACAAGGATGTGGCTCG
CCTGACCCAATTGCTCGAAACATCCAAGACCCTGACCGCCAATTTTTCCCAGTTGACCCTCGACGGCAGCGGCACCCAGT
TGCAGGAAACCACCGGCGACATGACCCTGCAGCGTCCGGGCCTGTTCTACTGGCACACCAATGCGCCAGCCGAGCAGACC
ATGGTGTCCGACGGCAAGAAAGTCACGCTGTGGGACCCGGACCTGGAACAGGCCACCATCAAGAAGCTTGATGAGCGTCT
GACCCAGACCCCGGCGCTGTTGCTGTCTGGCGACGTATCGAAGATCAGTCAGAGCTTTGACATCACCGCGAAAGAGGCCG
GTGGCGTGATCGACTTCACCCTGAAGCCGAAAACCAAGGACACGCTGTTCGACAGCCTGCGCCTGTCGTTCCGCAACGGT
CTGGTCAATGACATGCAACTGATCGACAGCGTCGGCCAGCGCACCAACATCCTGTTTACCGGTGTGAAGGCCAACGAAGC
GGTCCCGGCCTCGAAGTTCAAGTTCGACATCCCCAAGGGTGCCGATGTGATCCAGGAATAA

Upstream 100 bases:

>100_bases
CCCTGGCCCGGTACGCGACTGATTCGATACCCTGATCCAAATGCAATGGGCGGTGCATGAAGCGCCGTCCACTTTCCCAC
GAGTATTCAAGAGGACTCCC

Downstream 100 bases:

>100_bases
ACACAGAGGTTTCAACGGTACGTGATGGATCTGTTTCGCAGTGCACCGATTGCCCAGCCACTGGCTGCCCGTTTGCGGGC
GACCAATCTGGATGAGTACG

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRLIRMLLPVLALTTLTAHADDKDVARLTQLLETSKTLTANFSQLTLDGSGTQLQETTGDMTLQRPGLFYWHTNAPAEQT
MVSDGKKVTLWDPDLEQATIKKLDERLTQTPALLLSGDVSKISQSFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNG
LVNDMQLIDSVGQRTNILFTGVKANEAVPASKFKFDIPKGADVIQE

Sequences:

>Translated_206_residues
MRLIRMLLPVLALTTLTAHADDKDVARLTQLLETSKTLTANFSQLTLDGSGTQLQETTGDMTLQRPGLFYWHTNAPAEQT
MVSDGKKVTLWDPDLEQATIKKLDERLTQTPALLLSGDVSKISQSFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNG
LVNDMQLIDSVGQRTNILFTGVKANEAVPASKFKFDIPKGADVIQE
>Mature_206_residues
MRLIRMLLPVLALTTLTAHADDKDVARLTQLLETSKTLTANFSQLTLDGSGTQLQETTGDMTLQRPGLFYWHTNAPAEQT
MVSDGKKVTLWDPDLEQATIKKLDERLTQTPALLLSGDVSKISQSFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNG
LVNDMQLIDSVGQRTNILFTGVKANEAVPASKFKFDIPKGADVIQE

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=203, Percent_Identity=31.5270935960591, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_PSEPF (Q3KA81)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_349314.1
- ProteinModelPortal:   Q3KA81
- SMR:   Q3KA81
- STRING:   Q3KA81
- World-2DPAGE:   0008:Q3KA81
- GeneID:   3714973
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_3585
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   PRK00031
- BioCyc:   PFLU205922:PFL_3585-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22697; Mature: 22697

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIRMLLPVLALTTLTAHADDKDVARLTQLLETSKTLTANFSQLTLDGSGTQLQETTGD
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCEEEEECCCCCCHHHCCCC
MTLQRPGLFYWHTNAPAEQTMVSDGKKVTLWDPDLEQATIKKLDERLTQTPALLLSGDVS
EEEECCCEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCHH
KISQSFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNGLVNDMQLIDSVGQRTNILFT
HHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
GVKANEAVPASKFKFDIPKGADVIQE
ECCCCCCCCCCCEEEECCCCHHHHCC
>Mature Secondary Structure
MRLIRMLLPVLALTTLTAHADDKDVARLTQLLETSKTLTANFSQLTLDGSGTQLQETTGD
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCEEEEECCCCCCHHHCCCC
MTLQRPGLFYWHTNAPAEQTMVSDGKKVTLWDPDLEQATIKKLDERLTQTPALLLSGDVS
EEEECCCEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCHH
KISQSFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNGLVNDMQLIDSVGQRTNILFT
HHHHHCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
GVKANEAVPASKFKFDIPKGADVIQE
ECCCCCCCCCCCEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA