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The map label for this gene is ftsK [H]

Identifier: 77459808

GI number: 77459808

Start: 4051510

End: 4053918

Strand: Reverse

Name: ftsK [H]

Synonym: Pfl01_3586

Alternate gene names: 77459808

Gene position: 4053918-4051510 (Counterclockwise)

Preceding gene: 77459812

Following gene: 77459807

Centisome position: 62.96

GC content: 61.31

Gene sequence:

>2409_bases
TTGAAGAAATCCACGGAAGCACCAAAAACAGTCGTTCCGCTATGGCGTCAACAGTTGCACTACCGGCTCAAGGAAGGTGC
ATTGATCGCCATCGGCGCCTTGTGCCTGTTCCTGATGATGGCCTTGCTGACTTACGGCAAGGACGATCCGGGCTGGAGCC
ACAACAGCAAGATCGACGACGTGCAGAATTTCGGTGGCCCGGCGGGCTCCTACAGCGCCGACATCCTGTTCATGGTGCTG
GGGTACTTCGCGTACATCTTTCCGTTGCTGCTGGCGATCAAGGCGTATCAGATCTTCCGTCAGCGTCATGAGCCGTGGCA
GTGGAGCGGCTGGCTGTTCTCCTGGCGCCTGATCGGTCTGGTGTTTCTGGTGTTGTCCGGCGCTGCACTGGCGCACATTC
ATTTCCATGCAGCCACCGGATTGCCGGCCGGCGCGGGTGGAGCGCTGGGTGAAAGCCTCGGTGACCTGGCCCGCAACGCC
CTGAATATTCAGGGCAGCACGTTGCTGTTCATCGCGCTGTTTCTGTTCGGCCTGACGGTGTTCACCGACCTGTCGTGGTT
CAAGGTGATGGACATCACCGGCAAGATCACGCTTGACCTGTTCGAACTGTTCCAGGGCGCGCTAAACCGCTGGTGGTCGG
CGCGTACCGAGCGCAAGCAACTGGTCGCGCAGCTGCGTGAAGTCGACGATCGCGTGCATGACGTGGTTGCACCGACGGTC
ACCGACAAACGCGAGCAGGCCAAGGTCAAGGAACGTCTGATCGAGCGCGAACAGGCCCTCAGCAAACACATGTCCGAGCG
CGAGAAACAGGTGCCGCCGGTCATCGCCCCGGCCCCGGTCAAAGCGCCGGAGCCAAGCAAGCGCGTGCAGAAAGAGAAGC
AGGTGCCGTTGTTCGTCGACAGCGCCGTGGAAGGCACCTTGCCGCCGATCTCGATTCTCGATCCTGCGGAAAAGAAACAA
CTCAATTATTCGCCTGAATCCCTGGCGGCGGTCGGCCACTTGCTGGAGATCAAACTCAAGGAATTCGGCGTCGAAGTCAC
CGTGGATTCGATCCATCCGGGCCCGGTTATTACCCGTTACGAAATCCAGCCTGCTGCGGGCGTGAAGGTCAGCCGTATCG
CCAACCTGGCGAAAGACCTTGCACGTTCGCTGGCCGTGACCAGTGTGCGGGTGGTGGAAGTGATTCCGGGCAAGACCACG
GTCGGTATCGAAATTCCCAACGAAGACCGGCAGATCGTGCGCTTCTCCGAGGTGCTGTCGACGCCTGAGTATGACAACTT
CAAATCGCCGGTCACCCTGGCCCTGGGCCACGACATCGGCGGCAAGCCGGTCATCACCGACCTGGCGAAAATGCCGCACC
TGCTGGTGGCCGGTACGACCGGTTCCGGTAAGTCGGTGGGCGTGAACGCGATGATCCTGTCGATTCTGTTCAAGTCCGGC
CCGGACGACGCCAAGCTGATCATGATCGACCCGAAAATGCTCGAGCTGTCGATCTACGAAGGCATCCCGCACCTGCTGTG
CCCGGTCGTGACCGACATGAAGGACGCCGCCAACGCCCTGCGCTGGAGCGTGGCCGAGATGGAGCGTCGCTACAAGCTGA
TGGCGAAGATGGGCGTGCGAAACCTGTCCGGCTTCAACGCCAAGGTCAAGGAAGCCCAGGACGCCGGCGAGCCGCTGAGC
GATCCGCTGTACAAACGCGAAAGCATCCACGACGAAGCACCGCTGTTGCAGAAGCTGCCGACCATCGTCGTGGTCGTGGA
CGAATTCGCCGACATGATGATGATCGTCGGCAAGAAGGTAGAAGAACTGATCGCCCGTATCGCCCAGAAGGCGCGTGCGG
CCGGTATCCACCTGATCCTCGCGACCCAACGGCCGTCGGTGGATGTGATCACCGGTCTGATCAAGGCCAACATCCCGACA
CGGATGGCGTTCCAGGTATCGAGCAAGATCGACTCCCGGACCATCATCGACCAGGGCGGCGCCGAACAACTGCTCGGCCA
CGGTGACATGCTTTACATGCCGCCGGGCACCAGCCTGCCGATCCGGGTTCACGGCGCATTCGTGTCCGACGATGAAGTTC
ACCGGGTGGTTGAAGCCTGGAAACTGCGCGGCGCGCCGGAATACAACGACGACATCCTCAACGGTGTCGAAGAGGCGGGC
AGTGGTTTCGAAGGCAGCAGCGGCGGCGGTGACGGCGACGATCCGGAAGCCGACGCGCTGTACGACGAAGCCGTGCAGTT
CGTGCTCGAAAGCCGCCGTGCCTCCATCTCCGCTGTACAGCGCAAGCTGAAGATCGGCTACAACCGTGCCGCACGCATGA
TCGAAGCCATGGAAATGGCCGGGGTCGTGACGTCGATGAACACCAACGGTTCCCGCGAAGTCCTGGCCCCTGGCCCGGTA
CGCGACTGA

Upstream 100 bases:

>100_bases
GTCTCCGTTGCGCCCGTCAATTTTTTTACCTGCCTGGATTGGGCAGTTTTTTTCGTCATTCAATAGATGGACGCGCCTCT
GGCGCAGGAAAAGAAGCGTT

Downstream 100 bases:

>100_bases
TTCGATACCCTGATCCAAATGCAATGGGCGGTGCATGAAGCGCCGTCCACTTTCCCACGAGTATTCAAGAGGACTCCCAT
GCGTCTTATCCGCATGTTGC

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 802

Protein sequence:

>802_residues
MKKSTEAPKTVVPLWRQQLHYRLKEGALIAIGALCLFLMMALLTYGKDDPGWSHNSKIDDVQNFGGPAGSYSADILFMVL
GYFAYIFPLLLAIKAYQIFRQRHEPWQWSGWLFSWRLIGLVFLVLSGAALAHIHFHAATGLPAGAGGALGESLGDLARNA
LNIQGSTLLFIALFLFGLTVFTDLSWFKVMDITGKITLDLFELFQGALNRWWSARTERKQLVAQLREVDDRVHDVVAPTV
TDKREQAKVKERLIEREQALSKHMSEREKQVPPVIAPAPVKAPEPSKRVQKEKQVPLFVDSAVEGTLPPISILDPAEKKQ
LNYSPESLAAVGHLLEIKLKEFGVEVTVDSIHPGPVITRYEIQPAAGVKVSRIANLAKDLARSLAVTSVRVVEVIPGKTT
VGIEIPNEDRQIVRFSEVLSTPEYDNFKSPVTLALGHDIGGKPVITDLAKMPHLLVAGTTGSGKSVGVNAMILSILFKSG
PDDAKLIMIDPKMLELSIYEGIPHLLCPVVTDMKDAANALRWSVAEMERRYKLMAKMGVRNLSGFNAKVKEAQDAGEPLS
DPLYKRESIHDEAPLLQKLPTIVVVVDEFADMMMIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPT
RMAFQVSSKIDSRTIIDQGGAEQLLGHGDMLYMPPGTSLPIRVHGAFVSDDEVHRVVEAWKLRGAPEYNDDILNGVEEAG
SGFEGSSGGGDGDDPEADALYDEAVQFVLESRRASISAVQRKLKIGYNRAARMIEAMEMAGVVTSMNTNGSREVLAPGPV
RD

Sequences:

>Translated_802_residues
MKKSTEAPKTVVPLWRQQLHYRLKEGALIAIGALCLFLMMALLTYGKDDPGWSHNSKIDDVQNFGGPAGSYSADILFMVL
GYFAYIFPLLLAIKAYQIFRQRHEPWQWSGWLFSWRLIGLVFLVLSGAALAHIHFHAATGLPAGAGGALGESLGDLARNA
LNIQGSTLLFIALFLFGLTVFTDLSWFKVMDITGKITLDLFELFQGALNRWWSARTERKQLVAQLREVDDRVHDVVAPTV
TDKREQAKVKERLIEREQALSKHMSEREKQVPPVIAPAPVKAPEPSKRVQKEKQVPLFVDSAVEGTLPPISILDPAEKKQ
LNYSPESLAAVGHLLEIKLKEFGVEVTVDSIHPGPVITRYEIQPAAGVKVSRIANLAKDLARSLAVTSVRVVEVIPGKTT
VGIEIPNEDRQIVRFSEVLSTPEYDNFKSPVTLALGHDIGGKPVITDLAKMPHLLVAGTTGSGKSVGVNAMILSILFKSG
PDDAKLIMIDPKMLELSIYEGIPHLLCPVVTDMKDAANALRWSVAEMERRYKLMAKMGVRNLSGFNAKVKEAQDAGEPLS
DPLYKRESIHDEAPLLQKLPTIVVVVDEFADMMMIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPT
RMAFQVSSKIDSRTIIDQGGAEQLLGHGDMLYMPPGTSLPIRVHGAFVSDDEVHRVVEAWKLRGAPEYNDDILNGVEEAG
SGFEGSSGGGDGDDPEADALYDEAVQFVLESRRASISAVQRKLKIGYNRAARMIEAMEMAGVVTSMNTNGSREVLAPGPV
RD
>Mature_802_residues
MKKSTEAPKTVVPLWRQQLHYRLKEGALIAIGALCLFLMMALLTYGKDDPGWSHNSKIDDVQNFGGPAGSYSADILFMVL
GYFAYIFPLLLAIKAYQIFRQRHEPWQWSGWLFSWRLIGLVFLVLSGAALAHIHFHAATGLPAGAGGALGESLGDLARNA
LNIQGSTLLFIALFLFGLTVFTDLSWFKVMDITGKITLDLFELFQGALNRWWSARTERKQLVAQLREVDDRVHDVVAPTV
TDKREQAKVKERLIEREQALSKHMSEREKQVPPVIAPAPVKAPEPSKRVQKEKQVPLFVDSAVEGTLPPISILDPAEKKQ
LNYSPESLAAVGHLLEIKLKEFGVEVTVDSIHPGPVITRYEIQPAAGVKVSRIANLAKDLARSLAVTSVRVVEVIPGKTT
VGIEIPNEDRQIVRFSEVLSTPEYDNFKSPVTLALGHDIGGKPVITDLAKMPHLLVAGTTGSGKSVGVNAMILSILFKSG
PDDAKLIMIDPKMLELSIYEGIPHLLCPVVTDMKDAANALRWSVAEMERRYKLMAKMGVRNLSGFNAKVKEAQDAGEPLS
DPLYKRESIHDEAPLLQKLPTIVVVVDEFADMMMIVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPT
RMAFQVSSKIDSRTIIDQGGAEQLLGHGDMLYMPPGTSLPIRVHGAFVSDDEVHRVVEAWKLRGAPEYNDDILNGVEEAG
SGFEGSSGGGDGDDPEADALYDEAVQFVLESRRASISAVQRKLKIGYNRAARMIEAMEMAGVVTSMNTNGSREVLAPGPV
RD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=494, Percent_Identity=62.5506072874494, Blast_Score=609, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 87876; Mature: 87876

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHEECCCCCCCEEECCCCCCC
>Mature Secondary Structure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HHHEECCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]