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The map label for this gene is dgoR [H]

Identifier: 77459450

GI number: 77459450

Start: 3709746

End: 3710465

Strand: Direct

Name: dgoR [H]

Synonym: Pfl01_3228

Alternate gene names: 77459450

Gene position: 3709746-3710465 (Clockwise)

Preceding gene: 77459449

Following gene: 77459453

Centisome position: 57.62

GC content: 62.5

Gene sequence:

>720_bases
ATGGATTACCGCAAACCTTCCGACCGTAAAAGCATGCACTCGCGCATCGTCCAGGAACTGGGCATGCAGATTGTTTCCGG
ACGCTTTCTGCCCTGCGACAAACTGCCCGCCGAAGCCCTGCTCTGCGAGGAGTACGCGGTCAGCCGGCCGGTGTTGCGCG
AAGCCACGCGAGTGTTGGTCGCCAAGGGCCTGGTGTATTCCAAACCCCGCGTCGGCACCGTGGTCAAGCCGCGCCGCGAA
TGGCACATGCTCGACCCGGACGTGCTGCACTGGCTGATGCAAAGCAGCCCGCAGAACGAGTTCTTCAACGTCCTGACCAG
CGTGCGCAGCATCATCGAACCGGCCGCCGCCGCCCTCGCCGCCCAGCATGCCACCGATGCCGATATCGCGTCGATTGCCG
AGGCTTACCAGCGCATGGAAGCCGCACCGACCCCGGAAGCCTTGCTGCAACCGGATCTGGATTTCCATAGCCGGATTGCT
GACGCAACCCACAACGACTTGCTGGCCAACCTGTGCAACATGCTTGCGGTGGCGATTGCCGAGGCGCTGAAGCACTCCAA
CCAGCGGCCGAACCTGCATGAGCTGGCGTTGCCTCGACACAAGGCGATTTTGACGGCGATCGAGAATCGGGATGCGTTGG
GGGCGCGACATGCGACGTTGGTGCAGCTGGATGATGCGCGGAGTGCTTTGAGTGTGGTGCTGGGGGCGGATCTTTCGTAA

Upstream 100 bases:

>100_bases
TGATATTCATATTGACTGATACACCGCTATCGCGAGCAGGCTCGCTCCCACATTGCTATGATGCGCGGCATCTCCATCGC
TCAGGATCGCGCCACTCCCC

Downstream 100 bases:

>100_bases
GCCTTTAGTCCGCCTGCCCTCACCCTAGCCCTCTCCCAGGGGGAGAGGGAACCAATCTGGGGATATTGACGATCTACACC
GACGTGGACGATTTGCTTTG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDYRKPSDRKSMHSRIVQELGMQIVSGRFLPCDKLPAEALLCEEYAVSRPVLREATRVLVAKGLVYSKPRVGTVVKPRRE
WHMLDPDVLHWLMQSSPQNEFFNVLTSVRSIIEPAAAALAAQHATDADIASIAEAYQRMEAAPTPEALLQPDLDFHSRIA
DATHNDLLANLCNMLAVAIAEALKHSNQRPNLHELALPRHKAILTAIENRDALGARHATLVQLDDARSALSVVLGADLS

Sequences:

>Translated_239_residues
MDYRKPSDRKSMHSRIVQELGMQIVSGRFLPCDKLPAEALLCEEYAVSRPVLREATRVLVAKGLVYSKPRVGTVVKPRRE
WHMLDPDVLHWLMQSSPQNEFFNVLTSVRSIIEPAAAALAAQHATDADIASIAEAYQRMEAAPTPEALLQPDLDFHSRIA
DATHNDLLANLCNMLAVAIAEALKHSNQRPNLHELALPRHKAILTAIENRDALGARHATLVQLDDARSALSVVLGADLS
>Mature_239_residues
MDYRKPSDRKSMHSRIVQELGMQIVSGRFLPCDKLPAEALLCEEYAVSRPVLREATRVLVAKGLVYSKPRVGTVVKPRRE
WHMLDPDVLHWLMQSSPQNEFFNVLTSVRSIIEPAAAALAAQHATDADIASIAEAYQRMEAAPTPEALLQPDLDFHSRIA
DATHNDLLANLCNMLAVAIAEALKHSNQRPNLHELALPRHKAILTAIENRDALGARHATLVQLDDARSALSVVLGADLS

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=215, Percent_Identity=36.7441860465116, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI48994961, Length=177, Percent_Identity=28.8135593220339, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790032, Length=198, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786303, Length=174, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790780, Length=232, Percent_Identity=29.3103448275862, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789353, Length=198, Percent_Identity=27.7777777777778, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26385; Mature: 26385

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRKPSDRKSMHSRIVQELGMQIVSGRFLPCDKLPAEALLCEEYAVSRPVLREATRVLV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AKGLVYSKPRVGTVVKPRREWHMLDPDVLHWLMQSSPQNEFFNVLTSVRSIIEPAAAALA
HHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AQHATDADIASIAEAYQRMEAAPTPEALLQPDLDFHSRIADATHNDLLANLCNMLAVAIA
HHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALKHSNQRPNLHELALPRHKAILTAIENRDALGARHATLVQLDDARSALSVVLGADLS
HHHHHCCCCCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDYRKPSDRKSMHSRIVQELGMQIVSGRFLPCDKLPAEALLCEEYAVSRPVLREATRVLV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AKGLVYSKPRVGTVVKPRREWHMLDPDVLHWLMQSSPQNEFFNVLTSVRSIIEPAAAALA
HHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AQHATDADIASIAEAYQRMEAAPTPEALLQPDLDFHSRIADATHNDLLANLCNMLAVAIA
HHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALKHSNQRPNLHELALPRHKAILTAIENRDALGARHATLVQLDDARSALSVVLGADLS
HHHHHCCCCCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]