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The map label for this gene is yegH [H]

Identifier: 77459316

GI number: 77459316

Start: 3542235

End: 3543791

Strand: Reverse

Name: yegH [H]

Synonym: Pfl01_3094

Alternate gene names: 77459316

Gene position: 3543791-3542235 (Counterclockwise)

Preceding gene: 77459317

Following gene: 77459314

Centisome position: 55.04

GC content: 59.73

Gene sequence:

>1557_bases
ATGGAATGGTTAGCGGATCCCACGGCATGGCTGGGCTTGTTGACACTGATCGTGCTGGAACTGGTACTGGGTATCGACAA
CCTGGTGTTCATCGCGATCCTGGCGGACAAACTGCCGCCGCATCAGCGCGACCGCGCACGCATCATCGGTTTGAGCCTGG
CGCTGATCATGCGTCTTGGCCTGCTGGCGAGTATTTCCTGGCTGGTCACCCTCACGGCACCGTTGTTCGAGGTGTTCGGC
AAGAGCTTCTCCGGCCGTGACCTGATCATGCTGTTCGGTGGTGTGTTCCTGTTGTTCAAGGCGACCATGGAATTGCACGA
ACGGCTGGAAGGCCACATCGGTGAGCGCTCGACCAACACCGCTTATGCGCTGTTCTGGCCGATCGTGGCGCAGATCGTCG
TGCTCGACGCCGTGTTCTCCCTGGACGCGGTGATTACGGCCGTTGGCATGGTCGATGAACTGGCGGTGATGATGATTGCG
GTGATCGTGTCCATCGGTGTGATGATCGTTGCCAGCAAGCCGCTGACCCGCTTCGTCAATGCCCACCCGACGGTGATCAT
GCTGTGTCTGGGCTTCCTGATGATGATCGGTTTTGCCCTGACGGCCGAAGGCCTGGGCTTCCACATTCCGAAAGGTTATC
TGTACGCTGCCATTGGTTTCTCGATCCTGATCGAGATCTTCAACCAGATCGCCCGCGCTCGTCGCAAGCGCTCGATGCAG
GGCTTGCGACCGATGCGTGAGCGCACGGCTCACGCGGTGATGCGTCTGTTGGGTGGTCGCAAACTGGCGGTGGAAGAAGT
CGGCGAGGAAATCTCCGACTTGCTGGACAATGGTGAAGCGCCGAGCACGGAGCTGTTCGACCGTCGCGAGCGGGTGATGA
TCAGCGGTGTGCTGCAATTGGCCGAGCGACCGATTCGTGCCTTGATGACGGTGCGCGCCGATGTCGATCACATTGATCTG
GCCGACGACGCCGAGGCTATTCGTACACGGTTGATGCATTCGTCCTATTCGCGCTTGCCGTTGATTCGTAACGGCGCAGT
GGATGAGCCGCTGGGCTTCGTGCACAAGAAGGAACTGCTCAAGGAATACCTGGCCGGCAACGAGCCGAACCTTGAACACT
TGGCGCGCAAGACCGTCAATCTGCTGGACAGTTATTCGATCCTCAACGCACTGGAACAAATGCGTGCGGCCTCGACCCAC
ATTGCCTTTGTGGTGAACGAGTTCGGTGACTTTGTGGGTGTGTTGACCATGACCGACATTCTCGAGTCGATTGCCGGCGA
ACTGCCGGACGCCAGCGAAATCGCTGGCCCCGACGTGGTCGAGGAGCAGGGCGGGTTTATCGTCAACGGTGCGCTGAACC
TGACCCGCATCCGCGAACATACCGGTTTTCGCGCCGAGCCGACCGAGGATTACCAGACCCTGGCCGGGCTGGTGATGAGC
CTGCTGGATCGCCTGCCGATCAAGGGCGATCGTCTGCAGCATGAAGGCTGGGGCATGACCGTAATGGCAGTCGAAGAACG
TCGCGTGACGCGGGTGTTGCTGGTGCGTGAGGCGTGA

Upstream 100 bases:

>100_bases
CGACTACCGACTATCGTTGTAGGCGCAGCCTTCGAGCTTTCGCGCCGCACTTTGCCGTGTCCGGCAGCCTGAATTCACTG
ACGAGAGATAGAGACAGATT

Downstream 100 bases:

>100_bases
CGGCACTTTCATGAAAGGTTCCGCCGTTTTGCGCGGTGGACGGTGCAAAGGGTGCGGAGGGTGTCACGCAGCCAGTTCAG
GTCATGGGCCGATTTGTGCG

Product: integral membrane protein TerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MEWLADPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPHQRDRARIIGLSLALIMRLGLLASISWLVTLTAPLFEVFG
KSFSGRDLIMLFGGVFLLFKATMELHERLEGHIGERSTNTAYALFWPIVAQIVVLDAVFSLDAVITAVGMVDELAVMMIA
VIVSIGVMIVASKPLTRFVNAHPTVIMLCLGFLMMIGFALTAEGLGFHIPKGYLYAAIGFSILIEIFNQIARARRKRSMQ
GLRPMRERTAHAVMRLLGGRKLAVEEVGEEISDLLDNGEAPSTELFDRRERVMISGVLQLAERPIRALMTVRADVDHIDL
ADDAEAIRTRLMHSSYSRLPLIRNGAVDEPLGFVHKKELLKEYLAGNEPNLEHLARKTVNLLDSYSILNALEQMRAASTH
IAFVVNEFGDFVGVLTMTDILESIAGELPDASEIAGPDVVEEQGGFIVNGALNLTRIREHTGFRAEPTEDYQTLAGLVMS
LLDRLPIKGDRLQHEGWGMTVMAVEERRVTRVLLVREA

Sequences:

>Translated_518_residues
MEWLADPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPHQRDRARIIGLSLALIMRLGLLASISWLVTLTAPLFEVFG
KSFSGRDLIMLFGGVFLLFKATMELHERLEGHIGERSTNTAYALFWPIVAQIVVLDAVFSLDAVITAVGMVDELAVMMIA
VIVSIGVMIVASKPLTRFVNAHPTVIMLCLGFLMMIGFALTAEGLGFHIPKGYLYAAIGFSILIEIFNQIARARRKRSMQ
GLRPMRERTAHAVMRLLGGRKLAVEEVGEEISDLLDNGEAPSTELFDRRERVMISGVLQLAERPIRALMTVRADVDHIDL
ADDAEAIRTRLMHSSYSRLPLIRNGAVDEPLGFVHKKELLKEYLAGNEPNLEHLARKTVNLLDSYSILNALEQMRAASTH
IAFVVNEFGDFVGVLTMTDILESIAGELPDASEIAGPDVVEEQGGFIVNGALNLTRIREHTGFRAEPTEDYQTLAGLVMS
LLDRLPIKGDRLQHEGWGMTVMAVEERRVTRVLLVREA
>Mature_518_residues
MEWLADPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPHQRDRARIIGLSLALIMRLGLLASISWLVTLTAPLFEVFG
KSFSGRDLIMLFGGVFLLFKATMELHERLEGHIGERSTNTAYALFWPIVAQIVVLDAVFSLDAVITAVGMVDELAVMMIA
VIVSIGVMIVASKPLTRFVNAHPTVIMLCLGFLMMIGFALTAEGLGFHIPKGYLYAAIGFSILIEIFNQIARARRKRSMQ
GLRPMRERTAHAVMRLLGGRKLAVEEVGEEISDLLDNGEAPSTELFDRRERVMISGVLQLAERPIRALMTVRADVDHIDL
ADDAEAIRTRLMHSSYSRLPLIRNGAVDEPLGFVHKKELLKEYLAGNEPNLEHLARKTVNLLDSYSILNALEQMRAASTH
IAFVVNEFGDFVGVLTMTDILESIAGELPDASEIAGPDVVEEQGGFIVNGALNLTRIREHTGFRAEPTEDYQTLAGLVMS
LLDRLPIKGDRLQHEGWGMTVMAVEERRVTRVLLVREA

Specific function: Unknown

COG id: COG0861

COG function: function code P; Membrane protein TerC, possibly involved in tellurium resistance

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=231, Percent_Identity=24.6753246753247, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87082033, Length=518, Percent_Identity=51.3513513513513, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1788119, Length=520, Percent_Identity=51.3461538461538, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1789197, Length=236, Percent_Identity=49.1525423728814, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1790664, Length=232, Percent_Identity=23.7068965517241, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693175, Length=239, Percent_Identity=24.2677824267782, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786879, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 57345; Mature: 57345

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLADPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPHQRDRARIIGLSLALIMRLG
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLASISWLVTLTAPLFEVFGKSFSGRDLIMLFGGVFLLFKATMELHERLEGHIGERSTNT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AYALFWPIVAQIVVLDAVFSLDAVITAVGMVDELAVMMIAVIVSIGVMIVASKPLTRFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
AHPTVIMLCLGFLMMIGFALTAEGLGFHIPKGYLYAAIGFSILIEIFNQIARARRKRSMQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRPMRERTAHAVMRLLGGRKLAVEEVGEEISDLLDNGEAPSTELFDRRERVMISGVLQL
HCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AERPIRALMTVRADVDHIDLADDAEAIRTRLMHSSYSRLPLIRNGAVDEPLGFVHKKELL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KEYLAGNEPNLEHLARKTVNLLDSYSILNALEQMRAASTHIAFVVNEFGDFVGVLTMTDI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESIAGELPDASEIAGPDVVEEQGGFIVNGALNLTRIREHTGFRAEPTEDYQTLAGLVMS
HHHHHCCCCCCHHCCCCCCHHHCCCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LLDRLPIKGDRLQHEGWGMTVMAVEERRVTRVLLVREA
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHEEECC
>Mature Secondary Structure
MEWLADPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPHQRDRARIIGLSLALIMRLG
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LLASISWLVTLTAPLFEVFGKSFSGRDLIMLFGGVFLLFKATMELHERLEGHIGERSTNT
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AYALFWPIVAQIVVLDAVFSLDAVITAVGMVDELAVMMIAVIVSIGVMIVASKPLTRFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
AHPTVIMLCLGFLMMIGFALTAEGLGFHIPKGYLYAAIGFSILIEIFNQIARARRKRSMQ
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLRPMRERTAHAVMRLLGGRKLAVEEVGEEISDLLDNGEAPSTELFDRRERVMISGVLQL
HCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AERPIRALMTVRADVDHIDLADDAEAIRTRLMHSSYSRLPLIRNGAVDEPLGFVHKKELL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
KEYLAGNEPNLEHLARKTVNLLDSYSILNALEQMRAASTHIAFVVNEFGDFVGVLTMTDI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESIAGELPDASEIAGPDVVEEQGGFIVNGALNLTRIREHTGFRAEPTEDYQTLAGLVMS
HHHHHCCCCCCHHCCCCCCHHHCCCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LLDRLPIKGDRLQHEGWGMTVMAVEERRVTRVLLVREA
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]