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The map label for this gene is ompR [H]

Identifier: 77458928

GI number: 77458928

Start: 3113838

End: 3114563

Strand: Reverse

Name: ompR [H]

Synonym: Pfl01_2703

Alternate gene names: 77458928

Gene position: 3114563-3113838 (Counterclockwise)

Preceding gene: 77458933

Following gene: 77458927

Centisome position: 48.37

GC content: 63.91

Gene sequence:

>726_bases
ATGGATTGCGCAAACGTGAGCAGATTGCTGATCGTCGATGACGACGGGGAAATTCTGTCCTTGCTGAAGAAGTTCTTCGT
TCAGCACGGCTATCAGGTCGATGTCGCCGCCCATGGCGAGGCCATGTGGGCGGCCATTGCCCAGGCGCGGCCGGACACGA
TCATCCTCGACCTGATGCTGCCCGGCGAGGGCGGCCTGAGCCTGTGCCAGAAGGTCCGGGCGCAGATGGGCATTCCGATC
ATCATGCTCACGGCGATGGCAGAGTTGAGCGACCGCATTGTCGGCCTGGAACTGGGCGCCGACGACTACCTGACCAAACC
CTTTGCCCCGCAGGAATTGCTGGCCCGGGTGCGCGCGCTGCAACGTCGGGTCGGTGAGAACGCTCCGTCCGGCGCCGAGC
CTTCACGGCCGGTCATGGCCTTCGCCGGTTGGCATCTGGACATCACCTGCCGCGAACTGCGCTCGCCCGAAGGCGTGATG
ATTCCGATGTCCGCCGGCGAATTCGACCTGCTGCTGGTGTTGCTTGAACATCCGCAACGCATCCTGACCCGCGAACAACT
GATCGACCTGACCCACGGCCAGGGCCACGACGCCTATGACCGCAGCATCGACGTGCAGATCAGCCGGCTGCGGCGCAAGA
TCGAACCGGACAGCAAACGCCCGGACCTGATCCGCACGGTGCGCAACGGCGGCTACATGTTCACCGCCAAGGTCAGCCGC
TCATGA

Upstream 100 bases:

>100_bases
CCGACGATGTCCGGCTGATGTCCGCGCTGAAGGAATGTTGCAGGATTGAAATATATGACCGGCGCATCGAAATGGTTTTA
GATGCGCTTCTTTTGGGTTC

Downstream 100 bases:

>100_bases
TCGGCCGGATGCTGCGGCGCGACACCCTCAGCCGGCGGATTGCCCTGACAATCGTCGCGGCGATGCTCGCTTCGCTGCTG
CTCAATGCGCTGTTCGTTCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDCANVSRLLIVDDDGEILSLLKKFFVQHGYQVDVAAHGEAMWAAIAQARPDTIILDLMLPGEGGLSLCQKVRAQMGIPI
IMLTAMAELSDRIVGLELGADDYLTKPFAPQELLARVRALQRRVGENAPSGAEPSRPVMAFAGWHLDITCRELRSPEGVM
IPMSAGEFDLLLVLLEHPQRILTREQLIDLTHGQGHDAYDRSIDVQISRLRRKIEPDSKRPDLIRTVRNGGYMFTAKVSR
S

Sequences:

>Translated_241_residues
MDCANVSRLLIVDDDGEILSLLKKFFVQHGYQVDVAAHGEAMWAAIAQARPDTIILDLMLPGEGGLSLCQKVRAQMGIPI
IMLTAMAELSDRIVGLELGADDYLTKPFAPQELLARVRALQRRVGENAPSGAEPSRPVMAFAGWHLDITCRELRSPEGVM
IPMSAGEFDLLLVLLEHPQRILTREQLIDLTHGQGHDAYDRSIDVQISRLRRKIEPDSKRPDLIRTVRNGGYMFTAKVSR
S
>Mature_241_residues
MDCANVSRLLIVDDDGEILSLLKKFFVQHGYQVDVAAHGEAMWAAIAQARPDTIILDLMLPGEGGLSLCQKVRAQMGIPI
IMLTAMAELSDRIVGLELGADDYLTKPFAPQELLARVRALQRRVGENAPSGAEPSRPVMAFAGWHLDITCRELRSPEGVM
IPMSAGEFDLLLVLLEHPQRILTREQLIDLTHGQGHDAYDRSIDVQISRLRRKIEPDSKRPDLIRTVRNGGYMFTAKVSR
S

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=43.8297872340426, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=36.2869198312236, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=36.4035087719298, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.480686695279, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=38.1578947368421, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.618025751073, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=33.7662337662338, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=36.7256637168142, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI2367329, Length=237, Percent_Identity=36.2869198312236, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=33.4782608695652, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.8947368421053, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.7391304347826, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=32.034632034632, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.1688311688312, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=28.8888888888889, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26778; Mature: 26778

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCANVSRLLIVDDDGEILSLLKKFFVQHGYQVDVAAHGEAMWAAIAQARPDTIILDLML
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEEE
PGEGGLSLCQKVRAQMGIPIIMLTAMAELSDRIVGLELGADDYLTKPFAPQELLARVRAL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCHHCCCCCCHHHHHHHHHHH
QRRVGENAPSGAEPSRPVMAFAGWHLDITCRELRSPEGVMIPMSAGEFDLLLVLLEHPQR
HHHHCCCCCCCCCCCCCEEEEECCEEEEEHHHCCCCCCEEEEECCCCHHHHHHHHHCCHH
ILTREQLIDLTHGQGHDAYDRSIDVQISRLRRKIEPDSKRPDLIRTVRNGGYMFTAKVSR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEECC
S
C
>Mature Secondary Structure
MDCANVSRLLIVDDDGEILSLLKKFFVQHGYQVDVAAHGEAMWAAIAQARPDTIILDLML
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEEE
PGEGGLSLCQKVRAQMGIPIIMLTAMAELSDRIVGLELGADDYLTKPFAPQELLARVRAL
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCHHCCCCCCHHHHHHHHHHH
QRRVGENAPSGAEPSRPVMAFAGWHLDITCRELRSPEGVMIPMSAGEFDLLLVLLEHPQR
HHHHCCCCCCCCCCCCCEEEEECCEEEEEHHHCCCCCCEEEEECCCCHHHHHHHHHCCHH
ILTREQLIDLTHGQGHDAYDRSIDVQISRLRRKIEPDSKRPDLIRTVRNGGYMFTAKVSR
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEECC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]