Click here to switch to the map view.

The map label for this gene is oprD [H]

Identifier: 77458933

GI number: 77458933

Start: 3119197

End: 3120492

Strand: Reverse

Name: oprD [H]

Synonym: Pfl01_2708

Alternate gene names: 77458933

Gene position: 3120492-3119197 (Counterclockwise)

Preceding gene: 77458934

Following gene: 77458928

Centisome position: 48.47

GC content: 60.34

Gene sequence:

>1296_bases
ATGAAAGGTTTCATGCAACCGCGTTTCGCCCTGGCACTGTTGTATTGCGCAATGGCCGACTCGGCATTTGCCAGCGGATT
TCTCGACGACGCCAAGGCCGAAGTGCTCAGCCGCAACTTCTACCTGAGCAACGACTACCGCTCGCCCTCACCCGCCGGGA
AAAACTACAAACAGGAGTGGGCTCAGGGGTTTATCGGCACTTTCGCATCCGGTTTCACTGAAGGAATCGTCGGGGTTGGT
CTCGATGCCCACGCCTTTTATGGGCTGAAACTCGATGGCGGCAAGGGGCACTCCGGCACCGGACTTTTGCCGGTGGACAG
TGATGGCCGTAGCGAAAGCGAATACTCCAGCGCCGGTGGTGCGCTGAAGTTGAAGACTTCGAAAACCACCCTCGCCTTCG
GTGAAATGACCGTGGAAACGCCGGTCTTCGACACCTCGGACAAACGCCTGCAACCGGAATACGCCACGGGGTTGCTGCTC
GACAGCCACGAGATCGAAAACGCACGCGTCGTGGCCGGGCGCTTCACGGCGTTCAAGAACCAGGACCGTTCCTCCGGCAA
AGGCGACTTTCAAGGCTATGGCGCCAGCACCCAAGGCGAAAGCATCAGTTTTGTCGGCACCGATCTGTTCAGCGACAGCC
CGGTCGGCGGCGCGCTGTATGCGTCCGATCTGAGCGACACCTGGCGCCAGTACTACGCCAACCTGCATTTCAAACAGTCC
GGTCTGTTGCTCGACGCCAACGTCTACCACACCCGCGACACCGGACAGGCGTTGGCCGGCGACATCGACAACACCGCGTT
CAGCCTCTCGGGCAAATACACCTTCGGTGCCCACGCGGTGATGCTTGGCTGGCAGCGCATCAATGGCGACACGCCGTTCG
ATTTTGTCGGTGGCGATTCCATCTACCTGGCCAACTCGATCAAATACGCCGACTTCAACGGCGCTCACGAGCGCTCCTGG
CAAGCGCGTTATGACTTGGATCTCGGCGCCTTCGGCATTCCCGGGCTGAACTTCATGACCCGTTACGTTTCCGGCAGCCA
AATCGACGGCACTCACGCGCCCAAGGGCGGCGCCTACAACCCGTTCGACGCGGACTCCGGTGAATATCAGCCTCAGCAAG
GGGACGGCGGCAAACACTGGGAACGCGACATCGATCTGCGCTACATCGTCCAGTCCGGCGCGGCCAAGGATCTGTCGGTG
CAGCTGTCTCACGTTTCGCACCGGGCCAACAGCGCCCAGGCCGGGGATGACATTGACCGGATCTATGTGGTGATCCAGTA
CCCGTTGGGCTTTTGA

Upstream 100 bases:

>100_bases
CCGGGTGACCTGAGGACGCTGACTCAGCACATCCGCTCAATCGCAGCACGACGGTTTGCTTCAGTATCCGGCAACTTCCA
TCACGGCCGGTCACTGACAC

Downstream 100 bases:

>100_bases
GGGAAATTGGCGGAAGGCAGCCGGAGTCGAACCTGCCCGGGAACGGATGCCGTCCCCAACCGGGTTTGAAGCCCGGCCGC
GCCACCGGGCGCGATTGCCT

Product: outer membrane porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKGFMQPRFALALLYCAMADSAFASGFLDDAKAEVLSRNFYLSNDYRSPSPAGKNYKQEWAQGFIGTFASGFTEGIVGVG
LDAHAFYGLKLDGGKGHSGTGLLPVDSDGRSESEYSSAGGALKLKTSKTTLAFGEMTVETPVFDTSDKRLQPEYATGLLL
DSHEIENARVVAGRFTAFKNQDRSSGKGDFQGYGASTQGESISFVGTDLFSDSPVGGALYASDLSDTWRQYYANLHFKQS
GLLLDANVYHTRDTGQALAGDIDNTAFSLSGKYTFGAHAVMLGWQRINGDTPFDFVGGDSIYLANSIKYADFNGAHERSW
QARYDLDLGAFGIPGLNFMTRYVSGSQIDGTHAPKGGAYNPFDADSGEYQPQQGDGGKHWERDIDLRYIVQSGAAKDLSV
QLSHVSHRANSAQAGDDIDRIYVVIQYPLGF

Sequences:

>Translated_431_residues
MKGFMQPRFALALLYCAMADSAFASGFLDDAKAEVLSRNFYLSNDYRSPSPAGKNYKQEWAQGFIGTFASGFTEGIVGVG
LDAHAFYGLKLDGGKGHSGTGLLPVDSDGRSESEYSSAGGALKLKTSKTTLAFGEMTVETPVFDTSDKRLQPEYATGLLL
DSHEIENARVVAGRFTAFKNQDRSSGKGDFQGYGASTQGESISFVGTDLFSDSPVGGALYASDLSDTWRQYYANLHFKQS
GLLLDANVYHTRDTGQALAGDIDNTAFSLSGKYTFGAHAVMLGWQRINGDTPFDFVGGDSIYLANSIKYADFNGAHERSW
QARYDLDLGAFGIPGLNFMTRYVSGSQIDGTHAPKGGAYNPFDADSGEYQPQQGDGGKHWERDIDLRYIVQSGAAKDLSV
QLSHVSHRANSAQAGDDIDRIYVVIQYPLGF
>Mature_431_residues
MKGFMQPRFALALLYCAMADSAFASGFLDDAKAEVLSRNFYLSNDYRSPSPAGKNYKQEWAQGFIGTFASGFTEGIVGVG
LDAHAFYGLKLDGGKGHSGTGLLPVDSDGRSESEYSSAGGALKLKTSKTTLAFGEMTVETPVFDTSDKRLQPEYATGLLL
DSHEIENARVVAGRFTAFKNQDRSSGKGDFQGYGASTQGESISFVGTDLFSDSPVGGALYASDLSDTWRQYYANLHFKQS
GLLLDANVYHTRDTGQALAGDIDNTAFSLSGKYTFGAHAVMLGWQRINGDTPFDFVGGDSIYLANSIKYADFNGAHERSW
QARYDLDLGAFGIPGLNFMTRYVSGSQIDGTHAPKGGAYNPFDADSGEYQPQQGDGGKHWERDIDLRYIVQSGAAKDLSV
QLSHVSHRANSAQAGDDIDRIYVVIQYPLGF

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 46626; Mature: 46626

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFMQPRFALALLYCAMADSAFASGFLDDAKAEVLSRNFYLSNDYRSPSPAGKNYKQEW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHHH
AQGFIGTFASGFTEGIVGVGLDAHAFYGLKLDGGKGHSGTGLLPVDSDGRSESEYSSAGG
HHHHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCHHHCCCC
ALKLKTSKTTLAFGEMTVETPVFDTSDKRLQPEYATGLLLDSHEIENARVVAGRFTAFKN
EEEEEECCEEEEECCEEEECCCCCCCCCCCCCHHHCEEEEECCCCCCEEEEEEEEHHHCC
QDRSSGKGDFQGYGASTQGESISFVGTDLFSDSPVGGALYASDLSDTWRQYYANLHFKQS
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCCEEECC
GLLLDANVYHTRDTGQALAGDIDNTAFSLSGKYTFGAHAVMLGWQRINGDTPFDFVGGDS
CEEEECCEEECCCCCCHHHCCCCCCEEEECCCEEECCEEEEEEEEECCCCCCCEEECCCE
IYLANSIKYADFNGAHERSWQARYDLDLGAFGIPGLNFMTRYVSGSQIDGTHAPKGGAYN
EEEECCEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PFDADSGEYQPQQGDGGKHWERDIDLRYIVQSGAAKDLSVQLSHVSHRANSAQAGDDIDR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHCCCCCCCCCCCEE
IYVVIQYPLGF
EEEEEEECCCC
>Mature Secondary Structure
MKGFMQPRFALALLYCAMADSAFASGFLDDAKAEVLSRNFYLSNDYRSPSPAGKNYKQEW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHHH
AQGFIGTFASGFTEGIVGVGLDAHAFYGLKLDGGKGHSGTGLLPVDSDGRSESEYSSAGG
HHHHHHHHHHHHHHCCEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCHHHCCCC
ALKLKTSKTTLAFGEMTVETPVFDTSDKRLQPEYATGLLLDSHEIENARVVAGRFTAFKN
EEEEEECCEEEEECCEEEECCCCCCCCCCCCCHHHCEEEEECCCCCCEEEEEEEEHHHCC
QDRSSGKGDFQGYGASTQGESISFVGTDLFSDSPVGGALYASDLSDTWRQYYANLHFKQS
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCCEEECC
GLLLDANVYHTRDTGQALAGDIDNTAFSLSGKYTFGAHAVMLGWQRINGDTPFDFVGGDS
CEEEECCEEECCCCCCHHHCCCCCCEEEECCCEEECCEEEEEEEEECCCCCCCEEECCCE
IYLANSIKYADFNGAHERSWQARYDLDLGAFGIPGLNFMTRYVSGSQIDGTHAPKGGAYN
EEEECCEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PFDADSGEYQPQQGDGGKHWERDIDLRYIVQSGAAKDLSVQLSHVSHRANSAQAGDDIDR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEHHHHHCCCCCCCCCCCEE
IYVVIQYPLGF
EEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]