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The map label for this gene is xylB [H]

Identifier: 77458860

GI number: 77458860

Start: 3015575

End: 3017071

Strand: Reverse

Name: xylB [H]

Synonym: Pfl01_2635

Alternate gene names: 77458860

Gene position: 3017071-3015575 (Counterclockwise)

Preceding gene: 77458861

Following gene: 77458859

Centisome position: 46.86

GC content: 62.79

Gene sequence:

>1497_bases
ATGCACAAACAACAACTATTCCTCGGCATCGACTGCGGCACCCAAGGCACCAAAGCCATCATCCTCGACGCCACCAGCGG
TCAGGTGTTGGGCCAGGGCGCCGCCGCGCACACGATGATCAGCGGCGCCAACGGTCGTCGCGAACAAGACACCGCGCAAT
GGCTGGAAGCCTTCACCCTCGGCACCCGTCGCGCTTTATTGGCGGCAAATGTCGACGGCCAGTCGATCCTCGGCATCGGC
GTCTCCGGCCAACAACACGGCCTGGTACTGCTTGACGACCAAGGCCAGGTCCTGCGCCCGGCCAAGCTCTGGTGCGACAC
GGAGACCACACCAGAGAACGATCAACTGCTCGCTCATCTGGGCGGTGAGCAAGGCTCGCTGGAACGCCTCGGCGTGGTCA
TCGCGCCGGGCTACACCGTGTCCAAACTGTTGTGGACCAAGGAGCAGCATCCGAATGTGTTCTCCCGCATCGCGCGAGTT
CTGCTGCCCCACGACTACCTGAATTTCTGGCTCACCGGTCGTGCGTGCAGCGAATACGGCGATGCATCCGGCACCGGCTA
TTTCAATGTGCGCACCCGCCAATGGGATTTGCAGCTGCTGCGCGACATCGACGCCAGCGGCCGTCTACAATCCGCGCTGC
CGGAACTGATCGACGCCCATCAAGCGGTCGGCACGATCCTTCCCGCCATTGCCGAACAGCTGGGCATCAACCCTAACGCG
GTGGTTTCCAGCGGTGGCGGCGACAACATGATGGGCGCCATCGGCACCGGCAATATTCAGCCGGGGGCGATCACCATGAG
CCTCGGCTCTTCCGGCACGGTGTACGCCTACGCCGAGGCACCGAAGGTCAGCCCGGATGCGTCGGTCGCGACCTTCTGTT
CCTCGAGCGGCGGCTGGCTGCCGTTGATCTGCACCATGAACCTGACCAACGCCACCGGCGCAATCCGAGAACTGTTCAAC
CTCGATCTCGACGCCTTCAACGCTTTGGTAGCCCAGACCCCGATCGGCGCAGAAGGCGTAAGCATGTTGCCGTTCCTCAA
CGGCGAACGCGTGCCTCCCCTGCCTCATGCGACCGGCAGCCTGCATGGCCTGACGATCGATAACCTGACGCAAGCCAATC
TGTGCCGCGCCGCCGTCGAGGGCACCACCTTCGGCCTGCGTTATGGACTGGATCTGTTGCGCCAGAATGGTTTACAAAGC
CGCAGCATTTGCCTGATCGGCGGCGGTTCGAAAAGCGCGGTATGGCGGCAGATCGTCGCCGACATCATGAACACCCCGGT
GATCTGCACCGAGCAAAGCGAAGCCGCAGCCCTCGGCGCGGCGATTCAGGCGGCGTGGTGCAAATCGTGGTCGAACGGCC
ACGAAGACACCCTGGCCGATCTGTGCCAGCGCTGCGTGAAGCTCGACCTGAACAGTGAAACCCTCCCGGTTGCCGCGAAT
GTCGCGGCGTTCCAGCAGGCCTATGAACGCTATCGACTGCATGTCGCAACCTTATAA

Upstream 100 bases:

>100_bases
ACCTACACAAATCTGCTCCCTTTCCCCCTCTCCCCTCTGGGGAGAGGGTTGGGGTGAGGGGTGGCTTTAGAAGTCGCCAA
AAAACCAACAGGTTCACACC

Downstream 100 bases:

>100_bases
AGAGCAAACAACTATGTACCTGGTATGTGGCGAAGCACTGTTCGATTTCTTCAGCGAAGACGATGCCGGCGGGCAAGCGT
CGAAAGTCAATTTCAAGGCG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MHKQQLFLGIDCGTQGTKAIILDATSGQVLGQGAAAHTMISGANGRREQDTAQWLEAFTLGTRRALLAANVDGQSILGIG
VSGQQHGLVLLDDQGQVLRPAKLWCDTETTPENDQLLAHLGGEQGSLERLGVVIAPGYTVSKLLWTKEQHPNVFSRIARV
LLPHDYLNFWLTGRACSEYGDASGTGYFNVRTRQWDLQLLRDIDASGRLQSALPELIDAHQAVGTILPAIAEQLGINPNA
VVSSGGGDNMMGAIGTGNIQPGAITMSLGSSGTVYAYAEAPKVSPDASVATFCSSSGGWLPLICTMNLTNATGAIRELFN
LDLDAFNALVAQTPIGAEGVSMLPFLNGERVPPLPHATGSLHGLTIDNLTQANLCRAAVEGTTFGLRYGLDLLRQNGLQS
RSICLIGGGSKSAVWRQIVADIMNTPVICTEQSEAAALGAAIQAAWCKSWSNGHEDTLADLCQRCVKLDLNSETLPVAAN
VAAFQQAYERYRLHVATL

Sequences:

>Translated_498_residues
MHKQQLFLGIDCGTQGTKAIILDATSGQVLGQGAAAHTMISGANGRREQDTAQWLEAFTLGTRRALLAANVDGQSILGIG
VSGQQHGLVLLDDQGQVLRPAKLWCDTETTPENDQLLAHLGGEQGSLERLGVVIAPGYTVSKLLWTKEQHPNVFSRIARV
LLPHDYLNFWLTGRACSEYGDASGTGYFNVRTRQWDLQLLRDIDASGRLQSALPELIDAHQAVGTILPAIAEQLGINPNA
VVSSGGGDNMMGAIGTGNIQPGAITMSLGSSGTVYAYAEAPKVSPDASVATFCSSSGGWLPLICTMNLTNATGAIRELFN
LDLDAFNALVAQTPIGAEGVSMLPFLNGERVPPLPHATGSLHGLTIDNLTQANLCRAAVEGTTFGLRYGLDLLRQNGLQS
RSICLIGGGSKSAVWRQIVADIMNTPVICTEQSEAAALGAAIQAAWCKSWSNGHEDTLADLCQRCVKLDLNSETLPVAAN
VAAFQQAYERYRLHVATL
>Mature_498_residues
MHKQQLFLGIDCGTQGTKAIILDATSGQVLGQGAAAHTMISGANGRREQDTAQWLEAFTLGTRRALLAANVDGQSILGIG
VSGQQHGLVLLDDQGQVLRPAKLWCDTETTPENDQLLAHLGGEQGSLERLGVVIAPGYTVSKLLWTKEQHPNVFSRIARV
LLPHDYLNFWLTGRACSEYGDASGTGYFNVRTRQWDLQLLRDIDASGRLQSALPELIDAHQAVGTILPAIAEQLGINPNA
VVSSGGGDNMMGAIGTGNIQPGAITMSLGSSGTVYAYAEAPKVSPDASVATFCSSSGGWLPLICTMNLTNATGAIRELFN
LDLDAFNALVAQTPIGAEGVSMLPFLNGERVPPLPHATGSLHGLTIDNLTQANLCRAAVEGTTFGLRYGLDLLRQNGLQS
RSICLIGGGSKSAVWRQIVADIMNTPVICTEQSEAAALGAAIQAAWCKSWSNGHEDTLADLCQRCVKLDLNSETLPVAAN
VAAFQQAYERYRLHVATL

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI18860918, Length=420, Percent_Identity=22.6190476190476, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789987, Length=492, Percent_Identity=33.3333333333333, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1790005, Length=512, Percent_Identity=25.5859375, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787789, Length=468, Percent_Identity=23.9316239316239, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789168, Length=465, Percent_Identity=25.3763440860215, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554530, Length=531, Percent_Identity=23.9171374764595, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321633, Length=395, Percent_Identity=23.0379746835443, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356607, Length=553, Percent_Identity=24.0506329113924, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17864214, Length=469, Percent_Identity=24.0938166311301, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24654573, Length=411, Percent_Identity=24.0875912408759, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52839; Mature: 52839

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKQQLFLGIDCGTQGTKAIILDATSGQVLGQGAAAHTMISGANGRREQDTAQWLEAFTL
CCCCEEEEEEECCCCCCEEEEEECCCCCEEECCCHHHHEEECCCCCCHHHHHHHHHHHHH
GTRRALLAANVDGQSILGIGVSGQQHGLVLLDDQGQVLRPAKLWCDTETTPENDQLLAHL
CCCCEEEEECCCCCEEEEEECCCCCCCEEEECCCCCEECCHHEEECCCCCCCCCCEEEEE
GGEQGSLERLGVVIAPGYTVSKLLWTKEQHPNVFSRIARVLLPHDYLNFWLTGRACSEYG
CCCCCCHHHCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHEEEECCHHHHCC
DASGTGYFNVRTRQWDLQLLRDIDASGRLQSALPELIDAHQAVGTILPAIAEQLGINPNA
CCCCCEEEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VVSSGGGDNMMGAIGTGNIQPGAITMSLGSSGTVYAYAEAPKVSPDASVATFCSSSGGWL
EEECCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCCCEE
PLICTMNLTNATGAIRELFNLDLDAFNALVAQTPIGAEGVSMLPFLNGERVPPLPHATGS
EEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCC
LHGLTIDNLTQANLCRAAVEGTTFGLRYGLDLLRQNGLQSRSICLIGGGSKSAVWRQIVA
CCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
DIMNTPVICTEQSEAAALGAAIQAAWCKSWSNGHEDTLADLCQRCVKLDLNSETLPVAAN
HHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHH
VAAFQQAYERYRLHVATL
HHHHHHHHHHHEEEEECC
>Mature Secondary Structure
MHKQQLFLGIDCGTQGTKAIILDATSGQVLGQGAAAHTMISGANGRREQDTAQWLEAFTL
CCCCEEEEEEECCCCCCEEEEEECCCCCEEECCCHHHHEEECCCCCCHHHHHHHHHHHHH
GTRRALLAANVDGQSILGIGVSGQQHGLVLLDDQGQVLRPAKLWCDTETTPENDQLLAHL
CCCCEEEEECCCCCEEEEEECCCCCCCEEEECCCCCEECCHHEEECCCCCCCCCCEEEEE
GGEQGSLERLGVVIAPGYTVSKLLWTKEQHPNVFSRIARVLLPHDYLNFWLTGRACSEYG
CCCCCCHHHCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHEEEECCHHHHCC
DASGTGYFNVRTRQWDLQLLRDIDASGRLQSALPELIDAHQAVGTILPAIAEQLGINPNA
CCCCCEEEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VVSSGGGDNMMGAIGTGNIQPGAITMSLGSSGTVYAYAEAPKVSPDASVATFCSSSGGWL
EEECCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCCCCEE
PLICTMNLTNATGAIRELFNLDLDAFNALVAQTPIGAEGVSMLPFLNGERVPPLPHATGS
EEEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCC
LHGLTIDNLTQANLCRAAVEGTTFGLRYGLDLLRQNGLQSRSICLIGGGSKSAVWRQIVA
CCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHH
DIMNTPVICTEQSEAAALGAAIQAAWCKSWSNGHEDTLADLCQRCVKLDLNSETLPVAAN
HHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHH
VAAFQQAYERYRLHVATL
HHHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]