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The map label for this gene is yafC [C]

Identifier: 77458589

GI number: 77458589

Start: 2720489

End: 2721394

Strand: Direct

Name: yafC [C]

Synonym: Pfl01_2362

Alternate gene names: 77458589

Gene position: 2720489-2721394 (Clockwise)

Preceding gene: 77458585

Following gene: 77458590

Centisome position: 42.25

GC content: 61.7

Gene sequence:

>906_bases
ATGCAATCGTTCGTCATGGTGGTCGACACCGGCAGTATCACCGAGGCAGCCCGGCAACTGGGCACCGCCAAATCCATGGT
CAGCCAGCGGATTGCGCAACTGGAAAAACGACTCGGCAGCATCGTCCTCGAACGCGGGCGGCAGGCCCGGCTGACGGAGG
CCGGGGAGGTGTTTTATCGGTATTGCGTGCGGATTCTGTCGGAGGTCGAAGAGGCGGAAGACGCGGTGCTGGCCTTTCAA
TCGAGCCTGCGCGGCAGCCTGCGGCTGGCGGCGCCGATGGCGTTCAGCATTCGTTACCTGACGCCGATCCTGTCGTCCTT
CGCGGTACGCTATCCCGAGTTGCGCCTGGACATCGAATTCGACGATCGCCACGTCAACCTACACGAAGAACGCTACGACG
CGGCGATCCGCATCGGTGAGTTGCCGGACTCCTCGCTGGTGGCGAAAACCATCACCGCCAATCGTCATATCATTTGCGCC
AGTCCCGACTATCTGGCCGCTCATGGCACGCCGCAAACCCCGCAAGAACTGTCTGAACATTTCGCCATGCTCTACGTGAA
CCGCGAACCCCACGGCATGTGGACGCTGCCGGTGAACAATGCGCTGGAATCGTTTCGTGTGCGCTGCCGGATGCGCACCA
ACAACGGCCATCAGTTGATGGAGGCGGCGAAGGCCGGTATGGGGCTGGCGATTCTGCCGACGTTTCTGGCGGCGCAAGCT
ATCGTGGACGGTGAACTTCAGGAGGTGTTGGCGCCTTACGCGCCCCGAGGCGGGAATATTTCGGCGGTGTACCGACGCTC
CCAGCGGGCTTCACCCAAGTTGCAGGCGTTGACCGATTTTCTCTGCGAACAGATCGGCAATCCGCCGGTGTGGGAGCAAT
TGCTCGGGGCTCATTCGGCCGGTTAA

Upstream 100 bases:

>100_bases
GGCCCGTTTTCGGCTCTGGTGGGCGATGCCGGGCGAGCCGTAGATTGCGCCGTCCGAACCTTGCACACACTGGATGTAGA
ACTTGAACAAGCTTTGCGAG

Downstream 100 bases:

>100_bases
GGCGTTCGGGAAAAGCGAAACCGCGATTCGTTTTTCCCCGGCTTATGAGCCCTCGAACCCTTCAATAAGCTCTTCCTCAA
CAGGCGCGCTTTGACGCCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQSFVMVVDTGSITEAARQLGTAKSMVSQRIAQLEKRLGSIVLERGRQARLTEAGEVFYRYCVRILSEVEEAEDAVLAFQ
SSLRGSLRLAAPMAFSIRYLTPILSSFAVRYPELRLDIEFDDRHVNLHEERYDAAIRIGELPDSSLVAKTITANRHIICA
SPDYLAAHGTPQTPQELSEHFAMLYVNREPHGMWTLPVNNALESFRVRCRMRTNNGHQLMEAAKAGMGLAILPTFLAAQA
IVDGELQEVLAPYAPRGGNISAVYRRSQRASPKLQALTDFLCEQIGNPPVWEQLLGAHSAG

Sequences:

>Translated_301_residues
MQSFVMVVDTGSITEAARQLGTAKSMVSQRIAQLEKRLGSIVLERGRQARLTEAGEVFYRYCVRILSEVEEAEDAVLAFQ
SSLRGSLRLAAPMAFSIRYLTPILSSFAVRYPELRLDIEFDDRHVNLHEERYDAAIRIGELPDSSLVAKTITANRHIICA
SPDYLAAHGTPQTPQELSEHFAMLYVNREPHGMWTLPVNNALESFRVRCRMRTNNGHQLMEAAKAGMGLAILPTFLAAQA
IVDGELQEVLAPYAPRGGNISAVYRRSQRASPKLQALTDFLCEQIGNPPVWEQLLGAHSAG
>Mature_301_residues
MQSFVMVVDTGSITEAARQLGTAKSMVSQRIAQLEKRLGSIVLERGRQARLTEAGEVFYRYCVRILSEVEEAEDAVLAFQ
SSLRGSLRLAAPMAFSIRYLTPILSSFAVRYPELRLDIEFDDRHVNLHEERYDAAIRIGELPDSSLVAKTITANRHIICA
SPDYLAAHGTPQTPQELSEHFAMLYVNREPHGMWTLPVNNALESFRVRCRMRTNNGHQLMEAAKAGMGLAILPTFLAAQA
IVDGELQEVLAPYAPRGGNISAVYRRSQRASPKLQALTDFLCEQIGNPPVWEQLLGAHSAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=35.2941176470588, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=32.2033898305085, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=30.7958477508651, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI87081978, Length=283, Percent_Identity=30.3886925795053, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=29.020979020979, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787589, Length=259, Percent_Identity=28.1853281853282, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787128, Length=284, Percent_Identity=24.6478873239437, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=37.6068376068376, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790262, Length=235, Percent_Identity=26.3829787234043, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790011, Length=289, Percent_Identity=24.5674740484429, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=24.1496598639456, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=298, Percent_Identity=24.8322147651007, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33407; Mature: 33407

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFVMVVDTGSITEAARQLGTAKSMVSQRIAQLEKRLGSIVLERGRQARLTEAGEVFYR
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YCVRILSEVEEAEDAVLAFQSSLRGSLRLAAPMAFSIRYLTPILSSFAVRYPELRLDIEF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DDRHVNLHEERYDAAIRIGELPDSSLVAKTITANRHIICASPDYLAAHGTPQTPQELSEH
CCCCCCCHHHHHHHHEEECCCCCCHHHHHEECCCCEEEECCCCEEECCCCCCCHHHHHHC
FAMLYVNREPHGMWTLPVNNALESFRVRCRMRTNNGHQLMEAAKAGMGLAILPTFLAAQA
EEEEEEECCCCCEEEECHHHHHHHHEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
IVDGELQEVLAPYAPRGGNISAVYRRSQRASPKLQALTDFLCEQIGNPPVWEQLLGAHSA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCC
G
C
>Mature Secondary Structure
MQSFVMVVDTGSITEAARQLGTAKSMVSQRIAQLEKRLGSIVLERGRQARLTEAGEVFYR
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YCVRILSEVEEAEDAVLAFQSSLRGSLRLAAPMAFSIRYLTPILSSFAVRYPELRLDIEF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DDRHVNLHEERYDAAIRIGELPDSSLVAKTITANRHIICASPDYLAAHGTPQTPQELSEH
CCCCCCCHHHHHHHHEEECCCCCCHHHHHEECCCCEEEECCCCEEECCCCCCCHHHHHHC
FAMLYVNREPHGMWTLPVNNALESFRVRCRMRTNNGHQLMEAAKAGMGLAILPTFLAAQA
EEEEEEECCCCCEEEECHHHHHHHHEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
IVDGELQEVLAPYAPRGGNISAVYRRSQRASPKLQALTDFLCEQIGNPPVWEQLLGAHSA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]