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The map label for this gene is yveA [H]

Identifier: 77458536

GI number: 77458536

Start: 2663009

End: 2664640

Strand: Reverse

Name: yveA [H]

Synonym: Pfl01_2309

Alternate gene names: 77458536

Gene position: 2664640-2663009 (Counterclockwise)

Preceding gene: 77458539

Following gene: 77458535

Centisome position: 41.39

GC content: 62.81

Gene sequence:

>1632_bases
ATGTCAGGCCAAGGCAAGTTCAAAAAACAACTTTCATTGATCGACCTCACCTTTATCGGACTGGGGGCGATCTTCGGTTC
CGGCTGGTTGTTCGCGGCCAGTCACGTGTCGGCGATAGCCGGGCCGGCGGGGATTTTTTCCTGGTTGCTGGGCGGGTTCG
CCGTGTTGCTGCTGGGCATCGTCTACTGCGAGCTGGGCGCGGCATTGCCAAGGGCCGGCGGCGTGGTGCGTTACCCGGTT
TACAGCCACGGGCCGCTGCTCGGTTACTTGATGGGTTTCATCACGCTGATCGCGTTTTCCAGTCTGGTGGCGATTGAGGT
GGTTGCCTCTCGCCAATACGCGGCGGCCTGGTTTCCGAGCCTGACCAAGGCCGGCAGCGGTGATCCGACCCTGCTCGGCT
GGCTGGTGCAGTTCGGCCTGCTGTGCGTGTTCTTCCTGCTCAACTACCGCAGCGTGAAGACCTTCGCCAAGGCCAACAAT
CTGGTCAGCGTTTTCAAATTCATCGTGCCGCTGCTGGTGATCGGCGTGCTGTTCACCTTCTTCAAACCGGAAAACTTTCA
GATCCAAGGCTTCGCCCCTTTCGGACTCTCGGGCATCGAGATGGCCGTCTCTGCCGGCGGCGTGATCTTCGCCTACCTCG
GCCTGACCCCGATCATCTCGGTGGCCAGCGAAGTGAAGAACCCGCAACGCACCATCCCGATTGCGCTGATCCTGTCGGTG
CTGCTTTCCACTGCGATCTACGTGTTGCTGCAAACCGCCTTCCTCGGCGGCATTCCGACCGAATTGCTCGCCAATGGCTG
GGCCGGGGTTTCCAAGGAATTCGCCCTGCCGTACCGCGACATCGCCCTGGCGCTGGGCGTGGGCTGGCTGGCGTATCTGG
TGGTCGCCGACGCGGTAATCTCCCCCAGCGGCTGCGGCAACATCTACATGAACGCTACGCCTCGAGTGATCTACGGCTGG
GCGCAGACCGGCACCTTCTTCAAGGTCTTCACCCACATCGACGCGAAGTCCGGCATCCCGCGTCCGGCACTGTGGCTGAC
CTTCGCCCTGTCGGTGTTCTGGACCCTGCCGTTCCCATCGTGGGAAGCGTTGATCAACGTGGTGTCCGCCGCGCTGGTAC
TGAGCTACGCCGTCGCTCCAGTGACCGTCGCCGCGCTGCGTCGCAATGCCCCCGACATGCCGCGCCCGTTCCGGGTCAAG
TGCATGGGCGTGCTGGGGCCGGTGTCGTTCATCATCGCTGCGCTGATCGTTTACTGGTCGGGCTGGAACACCGTGTCCTG
GCTGCTCGGCCTGCAAATCCTGATGTTCGTCGTCTACCTGCTTTGCGGCCGCTTCGTGCCGACCGCTCAGCTCAGCCTGT
CCCGCCAAGTGCGCTCGTCGGCGTGGCTGATCGCCTTCTACGCCGTGACCATCGTCCTGTCGAAACTTGGCACCTTCGGC
GGTCTGGGCATCCTCACCCATCCATTCGACACCCTGGTCGTCGCAGCCTGTGCAATGGGCATTTATTACTGGGGCGCCGC
TACCGGCGTACCGGCACACCTGCTGCGCCTGGAATCCGAAGAGGATGAAAGCGAAGTCGCTTCGCCGTCCCCCGCCTCCA
CCGCCAATCCTCGCGCCGCCGGCGCTTACTGA

Upstream 100 bases:

>100_bases
CTGCGCAAAACATCAATCGCCCGACGCCCGATGAGTTCACTGTTTAGCCGTTCCAGTGACTCACACCTGCCTATCCAATA
ACTCACAAGAAGGCGATGCC

Downstream 100 bases:

>100_bases
AATCACTTAACGGGACCTGTCCATGAAACGAGTACACGTCATTGATTCCCACACCGGCGGCGAGCCCACGCGTCTGGTGA
TGAAAGGTTTTCCCGATCTG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: L-aspartate transporter [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MSGQGKFKKQLSLIDLTFIGLGAIFGSGWLFAASHVSAIAGPAGIFSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPV
YSHGPLLGYLMGFITLIAFSSLVAIEVVASRQYAAAWFPSLTKAGSGDPTLLGWLVQFGLLCVFFLLNYRSVKTFAKANN
LVSVFKFIVPLLVIGVLFTFFKPENFQIQGFAPFGLSGIEMAVSAGGVIFAYLGLTPIISVASEVKNPQRTIPIALILSV
LLSTAIYVLLQTAFLGGIPTELLANGWAGVSKEFALPYRDIALALGVGWLAYLVVADAVISPSGCGNIYMNATPRVIYGW
AQTGTFFKVFTHIDAKSGIPRPALWLTFALSVFWTLPFPSWEALINVVSAALVLSYAVAPVTVAALRRNAPDMPRPFRVK
CMGVLGPVSFIIAALIVYWSGWNTVSWLLGLQILMFVVYLLCGRFVPTAQLSLSRQVRSSAWLIAFYAVTIVLSKLGTFG
GLGILTHPFDTLVVAACAMGIYYWGAATGVPAHLLRLESEEDESEVASPSPASTANPRAAGAY

Sequences:

>Translated_543_residues
MSGQGKFKKQLSLIDLTFIGLGAIFGSGWLFAASHVSAIAGPAGIFSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPV
YSHGPLLGYLMGFITLIAFSSLVAIEVVASRQYAAAWFPSLTKAGSGDPTLLGWLVQFGLLCVFFLLNYRSVKTFAKANN
LVSVFKFIVPLLVIGVLFTFFKPENFQIQGFAPFGLSGIEMAVSAGGVIFAYLGLTPIISVASEVKNPQRTIPIALILSV
LLSTAIYVLLQTAFLGGIPTELLANGWAGVSKEFALPYRDIALALGVGWLAYLVVADAVISPSGCGNIYMNATPRVIYGW
AQTGTFFKVFTHIDAKSGIPRPALWLTFALSVFWTLPFPSWEALINVVSAALVLSYAVAPVTVAALRRNAPDMPRPFRVK
CMGVLGPVSFIIAALIVYWSGWNTVSWLLGLQILMFVVYLLCGRFVPTAQLSLSRQVRSSAWLIAFYAVTIVLSKLGTFG
GLGILTHPFDTLVVAACAMGIYYWGAATGVPAHLLRLESEEDESEVASPSPASTANPRAAGAY
>Mature_542_residues
SGQGKFKKQLSLIDLTFIGLGAIFGSGWLFAASHVSAIAGPAGIFSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVY
SHGPLLGYLMGFITLIAFSSLVAIEVVASRQYAAAWFPSLTKAGSGDPTLLGWLVQFGLLCVFFLLNYRSVKTFAKANNL
VSVFKFIVPLLVIGVLFTFFKPENFQIQGFAPFGLSGIEMAVSAGGVIFAYLGLTPIISVASEVKNPQRTIPIALILSVL
LSTAIYVLLQTAFLGGIPTELLANGWAGVSKEFALPYRDIALALGVGWLAYLVVADAVISPSGCGNIYMNATPRVIYGWA
QTGTFFKVFTHIDAKSGIPRPALWLTFALSVFWTLPFPSWEALINVVSAALVLSYAVAPVTVAALRRNAPDMPRPFRVKC
MGVLGPVSFIIAALIVYWSGWNTVSWLLGLQILMFVVYLLCGRFVPTAQLSLSRQVRSSAWLIAFYAVTIVLSKLGTFGG
LGILTHPFDTLVVAACAMGIYYWGAATGVPAHLLRLESEEDESEVASPSPASTANPRAAGAY

Specific function: Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=350, Percent_Identity=28, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI258614005, Length=447, Percent_Identity=24.8322147651007, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI258614003, Length=447, Percent_Identity=24.8322147651007, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI187423910, Length=403, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7657591, Length=403, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI258645169, Length=447, Percent_Identity=23.2662192393736, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI33286428, Length=408, Percent_Identity=25, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI114326544, Length=432, Percent_Identity=24.3055555555556, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI114326550, Length=432, Percent_Identity=24.3055555555556, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI181337167, Length=401, Percent_Identity=22.9426433915212, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI115648063, Length=463, Percent_Identity=21.8142548596112, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI115648022, Length=463, Percent_Identity=21.8142548596112, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI186910308, Length=446, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI186910306, Length=446, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI186910304, Length=446, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI4507047, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI7657683, Length=359, Percent_Identity=25.0696378830084, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082250, Length=361, Percent_Identity=29.3628808864266, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788480, Length=355, Percent_Identity=27.887323943662, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367353, Length=344, Percent_Identity=27.6162790697674, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786302, Length=413, Percent_Identity=23.4866828087167, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790653, Length=360, Percent_Identity=22.5, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786602, Length=440, Percent_Identity=22.9545454545455, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081708, Length=352, Percent_Identity=23.8636363636364, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=405, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=26.2773722627737, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540018, Length=411, Percent_Identity=25.7907542579075, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=25.9803921568627, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=411, Percent_Identity=26.2773722627737, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=423, Percent_Identity=25.0591016548463, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995388, Length=368, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990446, Length=353, Percent_Identity=25.2124645892351, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=315, Percent_Identity=24.7619047619048, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667468, Length=411, Percent_Identity=25.0608272506083, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45550968, Length=428, Percent_Identity=26.6355140186916, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921172, Length=428, Percent_Identity=26.6355140186916, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=25.9860788863109, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=25.9860788863109, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357367, Length=409, Percent_Identity=25.1833740831296, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24668806, Length=427, Percent_Identity=23.1850117096019, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356285, Length=427, Percent_Identity=23.1850117096019, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24668802, Length=427, Percent_Identity=23.1850117096019, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24651635, Length=416, Percent_Identity=24.5192307692308, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651633, Length=416, Percent_Identity=24.5192307692308, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221331183, Length=406, Percent_Identity=25.8620689655172, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17647653, Length=406, Percent_Identity=25.8620689655172, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24664379, Length=406, Percent_Identity=25.8620689655172, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161077963, Length=395, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641993, Length=401, Percent_Identity=22.1945137157107, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641995, Length=401, Percent_Identity=22.1945137157107, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 58024; Mature: 57893

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SGQGKFKKQLSLIDLTFIGLGAIFGSGWLFAASHVSAIAGPAGIFSWLLGGFAVLLLGI
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VYCELGAALPRAGGVVRYPVYSHGPLLGYLMGFITLIAFSSLVAIEVVASRQYAAAWFPS
HHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCH
LTKAGSGDPTLLGWLVQFGLLCVFFLLNYRSVKTFAKANNLVSVFKFIVPLLVIGVLFTF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKPENFQIQGFAPFGLSGIEMAVSAGGVIFAYLGLTPIISVASEVKNPQRTIPIALILSV
CCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLSTAIYVLLQTAFLGGIPTELLANGWAGVSKEFALPYRDIALALGVGWLAYLVVADAVI
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHC
SPSGCGNIYMNATPRVIYGWAQTGTFFKVFTHIDAKSGIPRPALWLTFALSVFWTLPFPS
CCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
WEALINVVSAALVLSYAVAPVTVAALRRNAPDMPRPFRVKCMGVLGPVSFIIAALIVYWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHC
GWNTVSWLLGLQILMFVVYLLCGRFVPTAQLSLSRQVRSSAWLIAFYAVTIVLSKLGTFG
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLGILTHPFDTLVVAACAMGIYYWGAATGVPAHLLRLESEEDESEVASPSPASTANPRAA
CCCHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCC
GAY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]