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The map label for this gene is 77458481

Identifier: 77458481

GI number: 77458481

Start: 2587166

End: 2588500

Strand: Direct

Name: 77458481

Synonym: Pfl01_2254

Alternate gene names: NA

Gene position: 2587166-2588500 (Clockwise)

Preceding gene: 77458479

Following gene: 77458482

Centisome position: 40.18

GC content: 63.67

Gene sequence:

>1335_bases
ATGGTTGCGCTTTCGTCCGGTCTTACCTGGCGCCATTGCCTGGCGTCATCCATCAGGGTCGGCGTGCTCGGCCTTGCCGT
ACTCGCTGGCAGCAGCGGGGTCTGGGCCGCGGATCCGTCGCAAGCCATTCGCCCGTACACCATCCATGTGGACGAAGCGA
AGCTGAGCGACCTGCGCAAACGCATCGCCGACACCCGCTGGCCGGACAAGGAAACGGTCGGCGACGTGTCCCAGGGAGTG
CAACTGGCGCAGGTCCAGGCGTTGGTGAAGTATTGGGGCGACGGCTACGACTGGCGCAAGGCCGAAGCGAAGCTCAACGC
GTTGCCGGAGTTCGTGACCACTATCGACGGCGTCGACATCCAGTTCATCCACGTGCGTTCGCGCAATCCCAACGCCATGC
CGCTGATCCTTACTCATGGCTGGCCGGGTTCGCAGTTCGAATTCCTCAAGACCATCGGCCCGCTGACCGATCCCGTGGCG
TACGGCGGCAAGGTCGAGGACTCGTTCGACGTGGTGATCCCGTCGATTCCCGGCCATGGTTTTTCCGGCAAACCGACCGA
GCTCGGCTGGGGCCCTGACCGGGTCGCGAAGGCCTGGGATGTGTTGATGACACGCCTGGGTTACAGCCATTACGTGTCCC
AGGGCGGCGATCATGGATCGGTGATATCCGATGCACTGGGTCGCCTGGCGCCGCCCGGTTTGCTGGGTATCCACCTGAAC
ATGCCGGCCACCGTGCCGCCGGAACTGGTCAAGCCAATCAACAGCGGCGACCCGGCCCCGGCCGGGTTGACCGCACCGGA
GGTGACGGCCTTCAACTCGCTGAGCCAGTTCTTCGGTCGTAACGCCGCCTATGGCGCAATGATGGTGACCCGTCCGCAAA
CCATCGGCTATCTGCTGGCTGACTCGCCCGCCGGCACGGCAGCCTGGATGTACGAAAAATTTGCCGCGTGGACCGACAGC
GACGGTCAGCCCGAGAAGGTCCTGAGTCGCGATGAAATGCTCGATGACATCAGCCTGTACTGGCTGACCGACAGCGGGGC
GTCGTCCTCCCGTTTCTACTGGGAGAACAACAACAATAACTTCAGTGCCGCCGCGCAGAAGACTGCCGACATCAAGGTGC
CGGTGGCGATCACCGTGTTCCCCCACGAAATCTACCGCGCGCCGAAAGTCTGGTCGCAGCGCGCCTATCCGTCGCTGGCT
TACTTCAGCGAAGTCAGCAAGGGCGGGCACTTCGCGGCATGGGAGCAACCGCAACTGTTCAGCGAAGAACTGCGCGAAGC
CTTCCGGCCACTGCGTGCGGCGGCGCAGAAAACCGCTGCGCAGGCAGCCCGCTAG

Upstream 100 bases:

>100_bases
AGGTATCGACCGACACCATCGTGTAATCCCCCCGGTGCCAGCGCAGTGGTCTGATCCGATTGGCGATGCCTTTCGAATAA
TGACTACAAGGAGATCCATC

Downstream 100 bases:

>100_bases
ACCTGCAATCCGCAAGCCCTTTAACCCACAGCCCTTTAACCCCAAGCCCGGAACCGCCGCCCGGCGGTTCACGAGGGAGA
CTCGGCATGACTGACTCTAA

Product: epoxide hydrolase-like protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MVALSSGLTWRHCLASSIRVGVLGLAVLAGSSGVWAADPSQAIRPYTIHVDEAKLSDLRKRIADTRWPDKETVGDVSQGV
QLAQVQALVKYWGDGYDWRKAEAKLNALPEFVTTIDGVDIQFIHVRSRNPNAMPLILTHGWPGSQFEFLKTIGPLTDPVA
YGGKVEDSFDVVIPSIPGHGFSGKPTELGWGPDRVAKAWDVLMTRLGYSHYVSQGGDHGSVISDALGRLAPPGLLGIHLN
MPATVPPELVKPINSGDPAPAGLTAPEVTAFNSLSQFFGRNAAYGAMMVTRPQTIGYLLADSPAGTAAWMYEKFAAWTDS
DGQPEKVLSRDEMLDDISLYWLTDSGASSSRFYWENNNNNFSAAAQKTADIKVPVAITVFPHEIYRAPKVWSQRAYPSLA
YFSEVSKGGHFAAWEQPQLFSEELREAFRPLRAAAQKTAAQAAR

Sequences:

>Translated_444_residues
MVALSSGLTWRHCLASSIRVGVLGLAVLAGSSGVWAADPSQAIRPYTIHVDEAKLSDLRKRIADTRWPDKETVGDVSQGV
QLAQVQALVKYWGDGYDWRKAEAKLNALPEFVTTIDGVDIQFIHVRSRNPNAMPLILTHGWPGSQFEFLKTIGPLTDPVA
YGGKVEDSFDVVIPSIPGHGFSGKPTELGWGPDRVAKAWDVLMTRLGYSHYVSQGGDHGSVISDALGRLAPPGLLGIHLN
MPATVPPELVKPINSGDPAPAGLTAPEVTAFNSLSQFFGRNAAYGAMMVTRPQTIGYLLADSPAGTAAWMYEKFAAWTDS
DGQPEKVLSRDEMLDDISLYWLTDSGASSSRFYWENNNNNFSAAAQKTADIKVPVAITVFPHEIYRAPKVWSQRAYPSLA
YFSEVSKGGHFAAWEQPQLFSEELREAFRPLRAAAQKTAAQAAR
>Mature_444_residues
MVALSSGLTWRHCLASSIRVGVLGLAVLAGSSGVWAADPSQAIRPYTIHVDEAKLSDLRKRIADTRWPDKETVGDVSQGV
QLAQVQALVKYWGDGYDWRKAEAKLNALPEFVTTIDGVDIQFIHVRSRNPNAMPLILTHGWPGSQFEFLKTIGPLTDPVA
YGGKVEDSFDVVIPSIPGHGFSGKPTELGWGPDRVAKAWDVLMTRLGYSHYVSQGGDHGSVISDALGRLAPPGLLGIHLN
MPATVPPELVKPINSGDPAPAGLTAPEVTAFNSLSQFFGRNAAYGAMMVTRPQTIGYLLADSPAGTAAWMYEKFAAWTDS
DGQPEKVLSRDEMLDDISLYWLTDSGASSSRFYWENNNNNFSAAAQKTADIKVPVAITVFPHEIYRAPKVWSQRAYPSLA
YFSEVSKGGHFAAWEQPQLFSEELREAFRPLRAAAQKTAAQAAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=407, Percent_Identity=34.6437346437346, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI209862837, Length=407, Percent_Identity=34.6437346437346, Blast_Score=258, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI17564944, Length=409, Percent_Identity=33.0073349633252, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI193207462, Length=415, Percent_Identity=25.7831325301205, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24655327, Length=408, Percent_Identity=32.1078431372549, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI20130139, Length=466, Percent_Identity=29.3991416309013, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19922580, Length=404, Percent_Identity=27.2277227722772, Blast_Score=162, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 48342; Mature: 48342

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALSSGLTWRHCLASSIRVGVLGLAVLAGSSGVWAADPSQAIRPYTIHVDEAKLSDLRK
CEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
RIADTRWPDKETVGDVSQGVQLAQVQALVKYWGDGYDWRKAEAKLNALPEFVTTIDGVDI
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
QFIHVRSRNPNAMPLILTHGWPGSQFEFLKTIGPLTDPVAYGGKVEDSFDVVIPSIPGHG
EEEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCCCC
FSGKPTELGWGPDRVAKAWDVLMTRLGYSHYVSQGGDHGSVISDALGRLAPPGLLGIHLN
CCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
MPATVPPELVKPINSGDPAPAGLTAPEVTAFNSLSQFFGRNAAYGAMMVTRPQTIGYLLA
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEE
DSPAGTAAWMYEKFAAWTDSDGQPEKVLSRDEMLDDISLYWLTDSGASSSRFYWENNNNN
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCC
FSAAAQKTADIKVPVAITVFPHEIYRAPKVWSQRAYPSLAYFSEVSKGGHFAAWEQPQLF
EEHHHHCCCCEEEEEEEEECCHHHHHCCHHHHHCCCCHHHHHHHHCCCCCEECCCCCHHH
SEELREAFRPLRAAAQKTAAQAAR
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVALSSGLTWRHCLASSIRVGVLGLAVLAGSSGVWAADPSQAIRPYTIHVDEAKLSDLRK
CEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHH
RIADTRWPDKETVGDVSQGVQLAQVQALVKYWGDGYDWRKAEAKLNALPEFVTTIDGVDI
HHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEE
QFIHVRSRNPNAMPLILTHGWPGSQFEFLKTIGPLTDPVAYGGKVEDSFDVVIPSIPGHG
EEEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCCCC
FSGKPTELGWGPDRVAKAWDVLMTRLGYSHYVSQGGDHGSVISDALGRLAPPGLLGIHLN
CCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
MPATVPPELVKPINSGDPAPAGLTAPEVTAFNSLSQFFGRNAAYGAMMVTRPQTIGYLLA
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEE
DSPAGTAAWMYEKFAAWTDSDGQPEKVLSRDEMLDDISLYWLTDSGASSSRFYWENNNNN
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCC
FSAAAQKTADIKVPVAITVFPHEIYRAPKVWSQRAYPSLAYFSEVSKGGHFAAWEQPQLF
EEHHHHCCCCEEEEEEEEECCHHHHHCCHHHHHCCCCHHHHHHHHCCCCCEECCCCCHHH
SEELREAFRPLRAAAQKTAAQAAR
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]