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The map label for this gene is hemK [C]

Identifier: 77458323

GI number: 77458323

Start: 2381370

End: 2382323

Strand: Direct

Name: hemK [C]

Synonym: Pfl01_2096

Alternate gene names: 77458323

Gene position: 2381370-2382323 (Clockwise)

Preceding gene: 77458322

Following gene: 77458324

Centisome position: 36.99

GC content: 63.1

Gene sequence:

>954_bases
ATGAATCAGGAAGAACAACTGTCCGCCAACGATCTGGTGCTGGTGCAACTGGGGCGGCGCCTGCAGGCCGACGGCTATCG
TTTCATCACCCCGACGCCGCTGACCCATCAACGGGTCAACCAGCGTGACGAAGGGCAGGCCGCCGATGGCCTGCGGGATG
TGTTCGGATGGTCGCGTCCTTTCGAACCGGGCCTTCTGTCTGCCGATGAACAGCGGCAATTGCAGGAAGCCCAGGTGATC
GATGAGTTCGACGGGCGCTTGAAGAGCCGGGTGCGCTGGTCGACCCTGGATGACTTGCTTTTCGTGCATTCCGGATTCCC
CACCGAAGCCGCCGACTCAGTGTTCTTCGGCCCGGACACCTATCGCTTTGCTCAACTGATCCACAGCCATTTGCAGCAGA
ACTTTGCGCCCATCCATCGGGCGGTGGACATCGGTTGTGGCGCCGGAGTGGGCGCGATCCTGATCGGCCGTGCCCGGCGC
GAAGCGCAAGTGCTGGCGGTGGATATCAACCCCGCTGCGCTGCGCCTGACCACGATCAACGCGGCGCTGGCCGAAGTGGC
CAACGTCGAAGTGCGCGCCAGTGATGTGTTGCAGGGCGTCGACGGCGAATTCGACCTGATCGTCGCCAACCCGCCCTACA
TGGCCGATCCGGCCGGGCGAGCTTACCGCCACGGTGGCGGGACGCTGGGGGCGGGCCTGTCGCTGCGTATCGTCGAACAG
GCGCTCAATCGCCTGACCCTCGGCGGCTCGCTGGTGCTTTATACCGGTGTGGCGATGGTCGATGGCCGCGATCCCTTCCT
CGATACCGTAGTGCCACGATTGGATGAAAAACGCTTCGGCTGGACCTACCGCGAACTCGATCCCGATGTGTTTGGTGAAG
AGTTGCTGAATCCAGGCTATCAGCGCGTCGACCGGATTGCCGTGGTCGCACTGACGGTGACTCGAACAGGCTGA

Upstream 100 bases:

>100_bases
TCCCGTGGCTCGCACCGTCGCGCCATGCACATCCGGCCGGGCTGCTCGCCACTCGCCGATTCATCCAACTCAAATCCGGC
CTGCGTTAAGGAATTCATCA

Downstream 100 bases:

>100_bases
AACAAGGCAGGTGCAGGATGAGCAGGAATCTCGACGACTACAACCGGATGCGCGACTTTTCAGCGACCTCTGAACCGGCG
GCTGGCCACCGCCGGGGCAA

Product: methyltransferase small

Products: NA

Alternate protein names: HemK Family Methylase; DNA Methylase; Methyltransferase; Methylase

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNQEEQLSANDLVLVQLGRRLQADGYRFITPTPLTHQRVNQRDEGQAADGLRDVFGWSRPFEPGLLSADEQRQLQEAQVI
DEFDGRLKSRVRWSTLDDLLFVHSGFPTEAADSVFFGPDTYRFAQLIHSHLQQNFAPIHRAVDIGCGAGVGAILIGRARR
EAQVLAVDINPAALRLTTINAALAEVANVEVRASDVLQGVDGEFDLIVANPPYMADPAGRAYRHGGGTLGAGLSLRIVEQ
ALNRLTLGGSLVLYTGVAMVDGRDPFLDTVVPRLDEKRFGWTYRELDPDVFGEELLNPGYQRVDRIAVVALTVTRTG

Sequences:

>Translated_317_residues
MNQEEQLSANDLVLVQLGRRLQADGYRFITPTPLTHQRVNQRDEGQAADGLRDVFGWSRPFEPGLLSADEQRQLQEAQVI
DEFDGRLKSRVRWSTLDDLLFVHSGFPTEAADSVFFGPDTYRFAQLIHSHLQQNFAPIHRAVDIGCGAGVGAILIGRARR
EAQVLAVDINPAALRLTTINAALAEVANVEVRASDVLQGVDGEFDLIVANPPYMADPAGRAYRHGGGTLGAGLSLRIVEQ
ALNRLTLGGSLVLYTGVAMVDGRDPFLDTVVPRLDEKRFGWTYRELDPDVFGEELLNPGYQRVDRIAVVALTVTRTG
>Mature_317_residues
MNQEEQLSANDLVLVQLGRRLQADGYRFITPTPLTHQRVNQRDEGQAADGLRDVFGWSRPFEPGLLSADEQRQLQEAQVI
DEFDGRLKSRVRWSTLDDLLFVHSGFPTEAADSVFFGPDTYRFAQLIHSHLQQNFAPIHRAVDIGCGAGVGAILIGRARR
EAQVLAVDINPAALRLTTINAALAEVANVEVRASDVLQGVDGEFDLIVANPPYMADPAGRAYRHGGGTLGAGLSLRIVEQ
ALNRLTLGGSLVLYTGVAMVDGRDPFLDTVVPRLDEKRFGWTYRELDPDVFGEELLNPGYQRVDRIAVVALTVTRTG

Specific function: Methylates The Translation Termination Release Factor Rf1 On Gln-235 And Rf2 On Gln-252. [C]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34843; Mature: 34843

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEEQLSANDLVLVQLGRRLQADGYRFITPTPLTHQRVNQRDEGQAADGLRDVFGWSRP
CCCCHHCCCCCEEEEECCCHHCCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHHHCCCCC
FEPGLLSADEQRQLQEAQVIDEFDGRLKSRVRWSTLDDLLFVHSGFPTEAADSVFFGPDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCEEECCCH
YRFAQLIHSHLQQNFAPIHRAVDIGCGAGVGAILIGRARREAQVLAVDINPAALRLTTIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEEEHH
AALAEVANVEVRASDVLQGVDGEFDLIVANPPYMADPAGRAYRHGGGTLGAGLSLRIVEQ
HHHHHHHCCEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHH
ALNRLTLGGSLVLYTGVAMVDGRDPFLDTVVPRLDEKRFGWTYRELDPDVFGEELLNPGY
HHHHHCCCCCEEEHCCEEEECCCCCHHHHHHHHCCCHHCCCCHHHCCHHHHHHHHCCCHH
QRVDRIAVVALTVTRTG
HHHHHEEEEEEEEEECC
>Mature Secondary Structure
MNQEEQLSANDLVLVQLGRRLQADGYRFITPTPLTHQRVNQRDEGQAADGLRDVFGWSRP
CCCCHHCCCCCEEEEECCCHHCCCCEEEECCCCCCHHHCCCCCCCCHHHHHHHHHCCCCC
FEPGLLSADEQRQLQEAQVIDEFDGRLKSRVRWSTLDDLLFVHSGFPTEAADSVFFGPDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCEEECCCH
YRFAQLIHSHLQQNFAPIHRAVDIGCGAGVGAILIGRARREAQVLAVDINPAALRLTTIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEEEHH
AALAEVANVEVRASDVLQGVDGEFDLIVANPPYMADPAGRAYRHGGGTLGAGLSLRIVEQ
HHHHHHHCCEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHH
ALNRLTLGGSLVLYTGVAMVDGRDPFLDTVVPRLDEKRFGWTYRELDPDVFGEELLNPGY
HHHHHCCCCCEEEHCCEEEECCCCCHHHHHHHHCCCHHCCCCHHHCCHHHHHHHHCCCHH
QRVDRIAVVALTVTRTG
HHHHHEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA